Computer-implemented process on image of biological sample
A technology for biological samples and digital images, applied in computing, image analysis, image enhancement, etc., to solve problems such as unsatisfactory automatic classification
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example 1
[0205] Figure 5 to Figure 16 A first example of the first embodiment of the present invention is shown. In this example, staining of tissue sections is performed using BIM.
[0206] Figure 5 A first digital image 103 (FIG. 1) is shown. Figure 6a Yes Figure 5 An enlarged view of a portion of the first digital image 103 . Figure 6b shown with Figure 6a The portion of the first digital image 103 shown in FIG. 1 corresponds to the portion of the second digital image 104 (FIG. 1).
[0207] Figure 7 is shown having as the first I 1 Gaussian curve 701 and the second I 1 The first histogram 601 of the fit of the sum of the Gaussian curve 702 ( Figure 4 ). Figure 8 is shown having as the first I 2 Gaussian curve 703 and the second I 2 The second histogram 602 of the fit of the sum of the Gaussian curve 704 ( Figure 4 ).
[0208] Figure 9a Shown is a picture 303 with point 705 submitted 403 to Organizational Scholar ( image 3 ). Figure 9b A picture 303 is s...
example 2
[0217] Figure 17 to Figure 28 A second example of the first embodiment of the present invention is shown. In this example, staining of tissue sections was performed using P-ERK.
[0218] Figure 17 A first digital image 103 (FIG. 1) is shown. Figure 18a Yes Figure 17 An enlarged view of a portion of the first digital image 103 . Figure 18b shown with Figure 18a The portion of the first digital image 103 shown in FIG. 1 corresponds to the portion of the second digital image 104 (FIG. 1).
[0219] Figure 19 is shown having as the first I 1 Gaussian curve 701 and the second I 1 The first histogram 601 of the fit of the sum of the Gaussian curve 702 ( Figure 4 ). Figure 20 is shown having as the first I 2 Gaussian curve 703 and the second I 2 The second histogram 602 of the fit of the sum of the Gaussian curve 704 ( Figure 4 ).
[0220] Figure 21a Shown is a picture 303 with point 705 submitted 403 to Organizational Scholar ( image 3 ). Figure 21b A pi...
example 3
[0229] Figure 29 to Figure 38 An example of the second embodiment of the present invention is shown. In this example, staining of the tissue section was performed using the three-color RGB3, where red corresponds to collagen fibers, cyan corresponds to cytoplasm, and violet corresponds to cell nuclei.
[0230] Figure 29 A first digital image 103 (FIG. 1) is shown. Figure 30a Yes Figure 29 An enlarged view of a portion of the first digital image 103 . Figure 30b shown with Figure 30a The portion of the first digital image 103 shown in FIG. 1 corresponds to the portion of the second digital image 104 (FIG. 1).
[0231] Figure 31a shown as I 1 and I 2 The two-dimensional distribution of the function of . The two-dimensional distribution forms a collection of one or more distributions. Each point 710 represents the value of a pixel in the second color space. Figure 31b shows the right Figure 31a Four Gaussian curves were fitted to the two-dimensional distribut...
PUM
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