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Application of Zhuang medicine root or leaf of cochinchina raspberry alcohol extract in preparation of anti-gouty arthritis medicines

A technology of gouty arthritis and Wuyepao, which is applied in the field of medicine to achieve the effect of easy operation of the preparation method, huge social and economic benefits, and inhibition of release

Active Publication Date: 2021-04-02
GUANGXI INST OF CHINESE MEDICINE & PHARMA SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] There is no report about the application of Wuyepao extract in gouty arthritis

Method used

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  • Application of Zhuang medicine root or leaf of cochinchina raspberry alcohol extract in preparation of anti-gouty arthritis medicines
  • Application of Zhuang medicine root or leaf of cochinchina raspberry alcohol extract in preparation of anti-gouty arthritis medicines
  • Application of Zhuang medicine root or leaf of cochinchina raspberry alcohol extract in preparation of anti-gouty arthritis medicines

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The method of extracting the ethanol extract of Wuyepao: take Wuyepao and add 8 times the amount of ethanol to extract 4 times, each time for 2 hours, the extracts are combined, filtered and concentrated to obtain the paste of Wuyepao ethanol extract.

Embodiment 2

[0028] The method of extracting the ethanol extract of Wuyepao: take Wuyepao and add 9 times the amount of ethanol to extract 3 times, each time for 3 hours, the extracts are combined, filtered and concentrated to obtain the paste of Wuyepao ethanol extract.

Embodiment 3

[0030] The method of extracting the ethanol extract of Wuyepao: take Wuyepao and add 10 times the amount of ethanol to extract 3 times, each time for 2.5 hours, the extracts are combined, filtered and concentrated to obtain the paste of Wuyepao ethanol extract.

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PUM

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Abstract

The invention discloses an application of a Zhuang medicine root or leaf of cochinchina raspberry alcohol extract in preparation of anti-gouty arthritis medicines, and the extraction method of the root or leaf of cochinchina raspberry alcohol extract comprises the following steps: adding 7-10 times of ethanol into root or leaf of cochinchina raspberry to proceed extraction for 3-4 times, 2-3 hourseach time, mixing the extracting solutions, filtering, and concentrating to obtain root or leaf of cochinchina raspberry alcohol extract paste; and adding auxiliary materials acceptable in clinical medicine to prepare traditional Chinese medicine dosage forms such as capsules, granules, tablets, pills, paste and the like. Experiments prove that the root or leaf of cochinchina raspberry alcohol extract can reduce the serum uric acid level of mice with hypeluricemia caused by hypoxanthine, has a good uric acid reducing effect, can relieve acute gouty arthritis related symptoms, can relieve joint injuries, can inhibit release of inflammatory factors; the alcohol extract has a patent medicine potential of preparing a medicinal preparation for preventing and treating gouty arthritis, providesa new material basis for developing anti-gouty arthritis medicines, and has potential and huge social and economic benefits.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to the use of the ethanol extract of the Zhuang medicine Auranthus quinquefolium as a medicine for preparing anti-gouty arthritis. Background technique [0002] Gouty arthritis is due to the deposition of urate in the joint capsule, bursa, cartilage, bone and other tissues, causing lesions and inflammatory reactions. It usually occurs at night, and the affected joints are severely painful. The first joint often involves the first metatarsophalangeal joint, followed by ankles and knees. Joint redness, swelling, heat and tenderness, general weakness, fever, headache, etc. Gout is a metabolic disease caused by abnormal purine metabolism leading to increased uric acid synthesis. The saturation of uric acid in the plasma leads to the deposition of monosodium urate crystals in the relatively vascular tissues around the distal joints. The appearance of such crystals can lead to acute i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61P19/06A61P19/02A61P9/10A61P9/12A61P13/12A61K125/00
CPCA61K36/73A61P19/06A61P19/02A61P9/10A61P9/12A61P13/12A61K2236/333A61K2236/53A61K2236/39Y02A50/30
Inventor 吕纪华王丽邓聿胤刘瑛饶伟源
Owner GUANGXI INST OF CHINESE MEDICINE & PHARMA SCI
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