33 results about "Acute gout arthritis" patented technology

The invention discloses a Chinese herbal compound preparation used for treating alcoholism and gout, mainly comprising the following components in parts by weight: 10-40 parts of kudzuvine root, 15-40 parts of hovenia acerba, 3-10 parts of pseudo-ginseng, 3-15 parts of phyllanthus emblica, 3-10 parts of fructus amomi, 35-10 parts of myristica fragrans, 3-15 parts of dchisandra chinensis, 4-15 parts of American olive, 10-20 parts of honeysuckle, 10-30 parts of rhizoma smilacis glabrae, 10-30 parts of coix seed, 10-30 parts of poria cocos, 10-20 parts of zaocys dhumnade, 10-20 parts of lucid ganoderma, 10-20 parts of American ginseng and 10-20 parts of turmeric. No hepatorenal dysfunction is caused when the compound preparation disclosed by the invention is used for treating hyperuricosuria, which shows that the preparation has no obvious toxic or side effect and mild medicine property, thus the preparation is beneficial to long-term administration. The inventor also knows that medicine taking compliance of patients and tolerance are good from some follow-up visited patients, annual attack frequency is reduced, and the preparation disclosed by the invention has obvious treatment effect on combined diabetes mellitus, hyperlipidemia and vascular hypertension, thus the preparation disclosed by the invention can be regarded as a safe Chinese herbal compound preparation which can be taken by a patient who is repeatedly attacked by acute gouty arthritis for a long time and can control symptoms and reduce attack frequency.

The invention discloses a traditional Chinese medicinal preparation for treating gout and a preparation method thereof. The traditional Chinese medicine is prepared from the following raw materials in part by weight: 1 to 30 parts of longhairy antenoron herb, 1 to 20 parts of clematis root, 1 to 20 parts of piper wallichii, 1 to 20 parts of lysimachia trientaloides hemsl, 1 to 20 parts of siphonostegia chinensis, 1 to 20 parts of oriental waterplantain rhizome and 1 to 10 parts of plantain herb. The traditional Chinese medicinal preparation is prepared from seven natural Chinese medicinal herbs, has the effects of clearing heat and eliminating stagnation and eliminating blood stasis and removing pain, has obvious anti-inflammatory effect and analgesic activity, and has good effects of treating acute gouty arthritis and various diseases during critical gout, difficult recurrence, and no obvious toxic or side effect or untoward effect.

The invention relates to a novel medical application of pulsatilla saponin B4, and particularly provides application of the pulsatilla saponin B4 in preparation of a medicine for treating treatment acute gouty arthritis.

The invention relates to reparation of 5-chloro-3-(4-methylsulfonyl) phenyl-2-(2-methyl-5-pyridyl) pyridine which is a high-selectivity cycloxygenase-2(COX-2) inhibitor, has the functions of preventing inflammation, clearing heat, relieving pain and the like, has a very good curative effect on signs and symptoms of osteoarthritis in the acute stage and the chronic stage and on the acute gouty arthritis, and is an important non-steride anti-inflammatory medicine. According to the method, the medicine is prepped by virtue of three steps as shown in the specification by taking 4-methylsulfonyl phenylacetic acid as a raw material.

The invention relates to a traditional Chinese medicine and application of its extracted composition in treating gout, and particularly relates to a traditional Chinese medicine. The traditional Chinese medicine is characterized by being prepared from, by weight, 0.5-2 parts of radix aconiti lateralis prepared, 2-8 parts of jasmine, 2-8 parts of endive root, 1-5 parts of szechwan Chinaberry fruit, 1-5 parts of semen plantaginis, and 1-6 parts of pueraria. The function of traditional Chinese medicine and its extractive in treating hyperuricemia and acute gout arthritis is better than allopurinol and colchicine; moreover, the toxic and side effects are low.

The invention provides a Zhuang medicine composition with a treatment effect on acute gouty arthritis, Zhuang medicine particles and a preparation method of the Zhuang medicine composition and the Zhuang medicine particles, and relates to the technical field of ethnic medicines. The Zhuang medicine composition is composed of glabrous sarcandra herb, rhizoma dioscoreae hypoglaucae, plantain herb, polygonum cuspidatum, cynanchum paniculatum, garden balsam stem, honeysuckle stem and liquorice, and clinical application results prove that the Zhuang medicine composition has the effects of clearing heat toxin, removing dampness toxin, dispelling wind toxin, relieving swelling pain, adjusting water channels, dredging long channels and fire channels, and has a remarkable curative effect on gout (gout) caused by wind-damp heat toxin. The Zhuang medicine composition and the Zhuang medicine granules based on the Zhuang medicine composition have very good curative effects on arthralgia, redness and swelling, scorching heat, unfavorable flexion and extension, blood uric acid increase, tophus and the like, and particularly, the Zhuang medicine composition and the Zhuang medicine granules based on the Zhuang medicine composition can be used for treating gouty arthritis induced by MSU crystals, and have the characteristics of multiple targets and low toxicity.

Provided are liposomes that encapsulate adenosine. The liposomes may be formed from sphingomyelin or a combination of sphingomyelin and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) or a combination of sphingomyelin and 1,2-dimyristoyl-sn-glycero-3-phosphorylglycerol (DMPG) or a combination of sphingomyelin, DMPG, and DMPC. The liposomes encapsulating adenosine may be used to induce cartilage regeneration, treat osteoarthritis, alleviate joint pain, and / or slow, arrest, and / or reverse progressive structural tissue damage associated with osteoarthritis or treat osteoarthritis, rheumatoid arthritis, acute gouty arthritis, and / or synovitis. The liposomes may release adenosine for up to two weeks.

The invention discloses a traditional Chinese medicine preparation for treating acute gout arthritis and belongs to the technical field of traditional Chinese medicine.Aiming at pathogenesis of acute gout arthritis and according to theories of treatment determination based on syndrome differentiation of traditional Chinese medicine, Campanula colorata Wall, nothapodytes pittosporoides, roots of mysorethorn, ligularia fischeri, Angiopteris fokiensis Hieron., pilea plataniflora, yichang viburnum branchlets and leaves, Chinese photinia leaves, Elaeagnus oldhamii Maxim., all grass of pendulousflower elsholtzia, uncaria macrophylla roots and Chonemorpha megacalyx Pierre are selected and decocted with water to form a decoction, and the effect is good through clinical tests.

The invention discloses the application of icariin in the preparation of anti-gout medicine. The invention adopts icariin as an anti-gout medicine, and it is verified through animal experiments that the prepared medicine composition can prevent and treat gouty arthritis, including acute gouty arthritis and chronic gouty arthritis. The material of the invention has wide sources, is easy to obtain, is simple and easy to be used for preparing medicine, and has good therapeutic effect.

The invention discloses a traditional Chinese medicine composition for treating acute gouty arthritis and a preparation method and application thereof; the traditional Chinese medicine composition is made from, by weight, 15-25 parts of Rhizoma Atractylodis, 10-20 parts of Cortex Phellodendri, 15-25 parts of Radix Achyranthis Bidentatae, 25-35 parts of Semen Coicis, 25-35 parts of Rhizoma Smilacis Glabrae, 15-25 parts of Rhizoma Dioscoreae Colletii, 5-15 parts of Lumbricus, 5-15 parts of Eupolyphaga seu Steleophaga, 25-35 parts of Radix Clematidis, 10-20 parts of Rhizoma Alismatis, 10-20 parts of Herba Lycopi, 10-20 parts of Radix Paeoniae Rubra, 5-15 parts of Semen Persicae, 10-20 parts of Radix Gentianae Macrophyllae, 15-25 parts of Radix Salviae Miltiorrhizae, 15-25 parts of Herba Plantaginis, 10-20 parts of Fructus Forsythiae, 5-15 parts of Rhizoma Acori Graminei, 15-25 parts of Rhizoma Atractylodis Macrocephalae, and 15-25 parts of Poria, 25-35 parts of Rhizoma Corydalis, and 4-10 parts of Scorpio. Scientific compatibility is made based on traditional syndrome differentiation in traditional Chinese medicine in conjunction with clinical practice, optimal doses of Chinese herbs are determined by repeated experiments, and the traditional Chinese medicine composition is significantly effective in treating acute gouty arthritis.

The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine preparation for external use, in particular to a traditional Chinese medicine gel for treating acute gouty arthritis and a preparation method thereof. The gel is composed of extracts of Arthia chinensis and Panax notoginseng and pharmaceutical excipients. It is made into a new dosage form for transdermal administration. It has passed the animal acute toxicity test, long-term toxicity test, skin irritation test, skin allergy test and other safety tests. According to the investigation, the results show that it is safe and reliable, and can avoid the toxic and side effects of systemic administration. The pharmacodynamic tests related to functional indications such as anti-inflammation and analgesia have proved to have a good therapeutic effect. Clinically used for the treatment of gouty arthritis, it can avoid various variable factors of the drug in the gastrointestinal tract and the first-pass effect of the liver, has high bioavailability, long-lasting effect, is convenient to use and can be interrupted at any time.

The invention relates to the technical field of traditional Chinese medicine formulas, and particularly discloses a traditional Chinese medicine composition for treating gout and a preparation methodthereof. The traditional Chinese medicine composition comprises, by mass, 20-28 parts of cassia twigs, 20-28 parts of radix paeoniae alba, 25-35 parts of poria cocos, 25-35 parts of yam rhizome, 25-35parts of radix rehmanniae recen, 9-15 parts of paris polyphylla, 15-21 parts of edible tulip, 25-35 parts of polygonum cuspidatum, 25-35 parts of hedyotis diffusa, 20-28 parts of honeysuckle stems. The traditional Chinese medicine composition is reasonable in compatibility, has the effects of clearing away heat and dampness, relieving wind and relieving diarrhea, and easing joint movement after all the medicines are used in cooperation, and can remarkably relieve the clinical symptoms of acute gouty arthritis related diseases and improve the quality of life of patients. Radix cyathulae, rhizoma anemarrhenae, cortex phellodendri and the like can be used in cooperation, the radix cyathulae is used as the medicine for introduction, the rhizoma anemarrhenae and cortex phellodendri are used asvarious medicine calamity yin impairment liquid for preventing bitter coldness, and the traditional Chinese medicine composition has the functions of clearing away heat and toxin, clearing away dampness to eliminate turbidity, and easing joint movement and is free of the yin impairment defect after all the medicines are used in cooperation.

The invention provides a liposome wrapping adenosine. The liposomes may be formed from sphingomyelin or a combination of sphingomyelin and 1, 2-dimyristoyl-sn-glycerol-3-phosphocholine (DMPC) or a combination of sphingomyelin and 1, 2-dimyristoyl-sn-glycerol-3-phosphoglycerol (DMPG) or a combination of sphingomyelin, DMPG and DMPC. The liposome wrapping adenosine can be used for inducing cartilage regeneration, treating osteoarthritis, alleviating arthralgia, and / or slowing, preventing and / or reversing progressive structural tissue damage associated with osteoarthritis, or treating osteoarthritis, rheumatoid arthritis, acute gouty arthritis and / or synovitis. The liposome can release adenosine for two weeks at most.