58 results about "Vascular hypertension" patented technology

The invention relates to a pharmaceutical composition used for lowering blood pressure. The pharmaceutical composition with azilsartan medoxomil and another one or two blood pressure lowering substances as active ingredients mainly comprises calcium ion antisticking agent, angiotensin converting enzyme inhibitor (ACEI) and hydrochlorothiazide. The composition provided by the invention can be prepared into an oral preparation and is used for treating vascular hypertension.

The invention discloses a traditional Chinese medicine oral liquid for lowering blood pressure and regulating blood fat and a preparation method thereof. The oral liquid is prepared from the following active pharmaceutical ingredients in parts by weight: 20-50 parts of gynostemma pentaphyllum, 10-30 parts of lotus leaf, 10-30 parts of chrysanthemum flower, 10-30 parts of hawthorn, 10-30 parts of Flos Buddlejae, 10-20 parts of wolfberry fruit, 5-20 parts of radix salviae miltiorrhizae and 2-10 parts of lophatherum gracile. The oral liquid is strict in prescription, has the effects of lowering blood pressure and blood fat, clearing heat, improving eyesight and the like, and has favorable curative effects on hypertension caused by hyperlipemia, dizziness, palpitation, asthenia, hyperlipemia, obesity and the like. All the active pharmaceutical ingredients except the gynostemma pentaphyllum are medicinal and edible drugs, so the oral liquid is safe to use; and the oral liquid contains abundant nutrient substances and effective components capable of improving human health and treating diseases, and thus, can supplement nutrients required by the human body and enhance the immunity.

A method employing pattern recognition techniques for identifying the functional status of patients with Pulmonary Hypertension is described. This method describes a process by which sets of cardiopulmonary exercise gas exchange variables are measured during rest, exercise and recovery and stored as unique data sets. The data sets are then analyzed by a series of feature extraction steps, yielding a multi-parametric index (MPI_PH) which reflects the current functional status of a patient. The method also employs a description scheme that provides a graphical image that juxtaposes the measured value of MPI to a reference classification system. An additional description scheme provides a trend plot of MPI values measured on a patient over time to provide feedback to the physician on the efficacy of therapy provided to the patient. The method will enable physicians to gather, view, and track complicated data using well-understood visualization techniques to better understand the consequences of their therapeutic actions.

The invention discloses a pharmaceutical composition of amrinone and application of the pharmaceutical composition in hypertension treatment. Amrinone and a novel-structure natural product compound (I) separated out of dried rhizomes of blackberry lily are contained in the pharmaceutical composition of amrinone, and when amrinone and the natural product compound (I) act independently, the treatment effect on renal vascular hypertension is achieved; when amrinone and the natural product compound (I) act jointly, the treatment effect on renal vascular hypertension is further improved, the pharmaceutical composition can be developed into medicine for treating renal vascular hypertension, and compared with the prior art, prominent substantive features and remarkable progress are achieved.

The invention relates to a depressurization chewing gum and a preparation method thereof, belonging to the technical field of gum. 2-40 percent by weight of Eucommia ulmoides depressurization active component or Eucommia ulmoides component depressurization active component, 50-97 percent of sugar alcohol and 1-10 percent of food additive are added into chewing gum so that the chewing gum becomes a health care food which is beneficial to the crowd with hypertension symptoms. The invention changes the characteristic of single function of the traditional chewing gum, endows the chewing gum with multiple functions of prevention and treatment of light and moderate hypertension diseases, adjuvant therapy of a severe hypertension disease, and the like and achieves the effect of promoting body health.

The invention discloses a herb tea for lowering blood pressure. The herb tea comprises the following active pharmaceutical ingredients in the mass ratio: 15-20 of folium mori, 14-18 of salvia miltiorrhiza, 9-12 of herba portulacae, 8-12 of fructus crataegi, 3-7 of folium ginkgo and 8-15 of catsia tora linn. The herb tea is prepared by selecting, cleaning, drying and grinding the active pharmaceutical ingredients, and evenly mixing in the mass ratio so as to obtain the mixed medicinal powder; bagging by using a conventional preparing method. A method for taking the herb tea is as follows: the herb tea is brewed in warm water to be taken and is taken three times a day, and one bag of the herb tea is taken each time, is brewed in 200ml of warm water to be taken and is repeatedly brewed to form tea for being drunk. The herb tea for lowering blood pressure is prepared from natural traditional Chinese medicinal materials, can lower the blood pressure and relieves the hypertension symptom; the herb tea for lowering blood pressure has an obvious effect and can prevent hypertension; and the herb tea for lowering blood pressure is suitable for people suffering from hypertension.

An excellent medicine for the treatment or prevention of hypertension or the like is provided. A specific acid addition salt of (R)-2-amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid 3-(1-diphenylmethylazetidin-3- yl)ester 5-isopropyl ester is useful as a medicine for the treatment or prevention of hypertension or the like.

The invention relates to a pu-er tea ferment soft capsule which is capable of regulating yin-yang, sedating, and lowering blood pressure and is used for various vascular hypertensions and various complicating diseases of heart, brain and kidney caused by vascular hypertension. The medicament comprises pu-er tea extract, aweto, lumbricus, black-snakes, monascus purpureus, rhizoma dioscorea, wolfberry fruit, cassia seeds, tortoise shells, fleece-flower roots, roots of red rooted salvia, round cardamom, angelica dahurica, tangerine peels, spine date seeds, ginkgo biloba, safflower, hawthorn, and the like. The production method comprises the following steps: hydrolyzing pu-er tea to prepare pu-er tea extract by using the purification and zymohydrolysis method, mixing the sundried powders such as aweto, lumbricus, tortoise shells, fleece-flower roots, roots of red rooted salvia, and the like to make soft capsules. In the invention, effective components are largely reserved due to the adoption of the purification and zymohydrolysis method, the medical value of the soft capsule can be fully improved; the preparation can improve blood oxygen saturation, is suitable for the diseases such as vexation, chest distress, short breath, hypertension, hyperlipidemia, arteriosclerosis, arrhythmia, myocardial ischemia, angina pectoris, coronary heart diseases, strokes, and the like.

The invention discloses a synbiotic compound preparation conducive to alleviation of hypertension symptoms without solid lesions. A formula of the synbiotic compound preparation comprises 8%-12% of bifidobacterium infantis, 8%-12% of bifidobacterium longum, 8%-12% of bifidobacterium breve, 3%-6% of lactobacillus acidophilus, 3%-6% of lactobacillus casei, 3%-6% of lactobacillus rhamnosus, 3%-6% oflactobacillus plantarum, 3%-6% of lactobacillus paracasei, 3%-6% of lactobacillus bulgaricus, 12%-18% of streptococcus thermophilus, 0.2%-0.8% of sodium acetate, 0.4-0.8% of sodium butyrate, 1.2%-1.5%of fructo-oligosaccharide, 0.5%-0.9% of lactulose, 0.1%-0.5% of barley malt powder, 1.4%-1.8% of skim sheep milk powder, 1.3%-1.8% of active hexose correlated compound, 0.8%-1.4% of inulin and 0.2%-0.5% of plantago ovate shell. The invention further discloses a preparation method of the synbiotic compound preparation conducive to alleviation of hypertension symptoms without solid lesions. The preparation method includes steps of quantitative weighing, probiotic culture, probiotic fermentation, skim sheep milk resuspension and mixing for capsule preparation.

The invention discloses an oral medicine composition for treating obesity or vascular hypertension, and belongs to the field of medicine. The medicine composition comprises Orlistat or Cetilista and active ingredients of dipine medicine. In the medicine composition, the use amount of Orlistat or Cetilista and dipine medicine is greatly reduced; particularly, a sustained-release capsule prepared from the medicinal composition can achieve the treatment effect after being taken once a day only, so that the benefit/cost is increased, the patient compliance is improved, and the social value is higher.

The invention relates to a telmisartan pharmaceutical composition for treating vascular hypertension, and belongs to the technical field of medicines. The technical scheme of the invention is characterized by adopting a micronization technology: a mixture of a main drug, sodium hydroxide and mannitol is micronized by an air-flow pulverizer, the D90 of the micronized mixture of telmisartan, sodium hydroxide and mannitol is between 3.0 [mu]m and 5.0 [mu]m. According to the technical scheme of the invention, a preparation method of telmisartan tablets is simplified, the preparation period is shortened, the material consumption is reduced, and moreover, the tablets are ensured to have higher dissolution rate; and secondly, through the use of the micronization technology, the drug dissolution rate is improved, the particles prepared by the micronization technology have quite good fluidity and compressibility, sorbitol having quite strong hygroscopicity is not required to be used, and the stability of the sample is improved.

The invention discloses a traditional Chinese medicine oral liquid for lowering blood pressure, preventing dizziness and regulating blood fat and a preparation method thereof. The oral liquid is prepared from the following active pharmaceutical ingredients in parts by weight: 20-50 parts of gynostemma pentaphyllum, 10-30 parts of honeysuckle flower, 10-30 parts of chrysanthemum flower, 10-30 parts of hawthorn, 10-30 parts of fructus momordicae, 10-20 parts of wolfberry fruit, 5-20 parts of radix salviae miltiorrhizae, 2-10 parts of lophatherum gracile and 2-10 parts of purslane. The oral liquid is strict in prescription, has the effects of lowering blood pressure and blood fat, clearing heat, improving eyesight and the like, and has favorable curative effects on hypertension caused by hyperlipemia, dizziness, palpitation, asthenia, hyperlipemia, obesity and the like. All the active pharmaceutical ingredients except the gynostemma pentaphyllum are medicinal and edible drugs, so the oral liquid is safe to use; and the oral liquid contains abundant nutrient substances and effective components capable of improving human health and treating diseases, and thus, can supplement nutrients required by the human body and enhance the immunity.

The invention discloses a plantain seed tea beverage for preventing and treating vascular hypertension. The plantain seed tea beverage is characterized by adopting the following raw materials in parts by weight: 100 to 120 parts of plantain seed, 60 to 80 parts of semen cassiae, 15 to 25 parts of semen celosiae, 8 to 16 parts of salvia miltiorrhiza and 15 to 20 parts of mint. A preparation method of the plantain seed tea beverage comprises the following steps that raw materials are made into drinking tablets, and the package is carried out after the mixing. A drinking method comprises the following steps that 2 to 4g of drinking tablets are taken each time and are placed into a cup to be soaked by boiling water, and the liquor can be drunk after 3 minutes. After the liquor is drunk to 2/3, the boiling water is added again for brewing, and the drinking tablets can be generally brewed for 4 to 6 times. The plantain seed tea beverage has the effects of dispelling wind and heat, reducing lipid, brightening the eyes, alleviating water retention and relaxing the bowels, and has the obvious effects when being used for the prevention and the auxiliary treatment on vascular hypertension.

The invention discloses carboxyl group-containing benzothiadiazide derivatives, a preparation method thereof, a medicine composition containing the compound and an application thereof in treatment or prevention for complications of vascular hypertension and serum hyperuricemia and/or hypercholesteremia. The benzothiadiazide derivative compounds meet a general formula (I) specified in the description. The carboxyl group-containing benzothiadiazide derivatives are synthesised by a one-step method, as well as are simple in synthesis process, simple in separation and purification methods, high in yield, good in repeatability, free of strong acid-resistant special equipment, and suitable for large-batch production.

The invention relates a pharmaceutical composition comprising a combination of:

• (i) the AT 1-antagonist vaisertan or a pharmaceutically acceptable salt thereof; and
• (ii) a NEP inhibitor or a pharmaceutically acceptable salt thereof and optionally a pharmaceutically acceptable carrier and to a method for the treatment or prevention of a condition or disease

selected from the group consisting of hypertension, heart failure, such as (acute and chronic) congestive heart failure, left ventricular dysfunction and hypertrophic cardiomyopathy, diabetic cardiac myopathy, supraventricular and ventricular arrhythmias, atrial fibrillation, atrial flutter, detrimental vascular remodeling, myocardial infarction and its sequelae, atherosclerosis, angina (whether unstable or stable), renal insufficiency (diabetic and non-diabetic), heart failure, angina pectoris, diabetes, secondary aldosteronism, primary and secondary pulmonary hypertension, renal failure conditions, such as diabetic nephropathy, glomerulonephritis, scleroderma, glomerular sclerosis, proteinuria of primary renal disease, and also renal vascular hypertension, diabetic retinopathy, the management of other vascular disorders, such as migraine, peripheral vascular disease, Raynaud's disease, luminal hyperplasia, cognitive dysfunction, such as Alzheimer's, glaucoma and stroke, comprising administering a therapeutically effective amount of the pharmaceutical composition to a mammal in need thereof.

The invention discloses a pharmaceutical composition of ambroxol hydrochloride and application thereof in biological medicines. The pharmaceutical composition of ambroxol hydrochloride provided by the invention comprises ambroxol hydrochloride, and a natural product compound (I) which has a novel structure and is separated from dried roots and rhizomes of Notopterygium incisum. The composition of ambroxol hydrochloride and the compound (I) provided by the invention can significantly reduce the concentration of angiotensin II and the activity of renin in a hypertensive rat model; meanwhile, the effects of the composition are superior to the independent effects of ambroxol hydrochloride or the compound (I). The composition of ambroxol hydrochloride and the compound (I) can be developed into drugs used for treating renal vascular hypertension; and compared with the prior art, the composition has excellent substantial characteristics and significant advancement.

A composite Chinese medicine in the form of dripping pill and soft capsule for treating hypertension, dizziness, palpitation, dreamfull sleep, etc, and its preparing process are disclosed.

The invention relates to the use of 1-aminocyclopropanecarboxylic acid (ACPC) in preparing medicine for treating cerebrovascular and cardiovascular diseases, in particular the use in preparing medicament for treating hypertension, cerebrovascular thrombus and cerebral apoplexy.

The invention provides a traditional Chinese medicine composition for treating hypertension and belongs to the technical field of Chinese herbal medicine preparations. The invention aims at providing the traditional Chinese medicine composition for treating hypertension. The traditional Chinese medicine composition for treating hypertension can be used for retarding and treating vascular hypertension. According to the technical scheme, the traditional Chinese medicine composition for treating hypertension comprises the following raw materials in parts by weight: 28-35 parts of herba artemisiae scopariae, 8-12 parts of gardenia, 8-12 parts of concha haliotidis, 3-6 parts of radix bupleuri, 12-18 parts of radix scutellariae, 8-12 parts of poria cocos and 28-35 parts of kelp. The traditional Chinese medicine composition for treating hypertension has the advantages of strengthening heart qi, protecting heart-yin and heart-yang, tonifying spleen and invigorating stomach, reinforcing vital essence, calming liver-yang, tonifying qi and nourishing blood, conditioning internal organs, improving endothelial functions of arteries, and promoting blood circulation and dissolving blood stasis so as to reduce blood pressure.

The invention provides a speech recognition high blood pressure symptom acquisition and artificial intelligence analysis device. The speech recognition high blood pressure symptom acquisition and artificial intelligence analysis device includes a temperature monitoring sensor interface, a blood oxygen monitoring sensor interface, an electrocardiogram monitoring sensor interface, a blood pressure monitoring module interface, a data transmission interface, a power switch, a temperature monitoring sensor, a blood oxygen monitoring sensor, an electrocardiogram monitoring sensor, a blood pressure monitoring module, a voice receiving device, a speech recognition device, a central processing device, a wireless transmission device, a mobile device, a data intelligent analysis unit, a power controlunit, a storage device and a display device. The blood pressure monitoring module includes a blood pressure monitoring sensor and a signal processing circuit. A health status of patients after the patients take high blood pressure drugs is monitored through various health parameter detection devices. Through the blood pressure monitoring sensor and the signal processing circuit, the accuracy of blood pressure monitoring is improved, and through the data intelligent analysis unit, the high blood pressure data of the patients are analyzed emphatically.

The invention discloses a traditional Chinese medicine composition, a preparation of the traditional Chinese medicine composition and a preparation method and application of the preparation. The traditional Chinese medicine composition is prepared from 10-15 parts of ganoderma sinensis, 10-15 parts of radix achyranthis bidentatae, 1-3 parts of pericarpium citri reticulatae, 10-15 parts of eucommia ulmoides, 10-15 parts of poria cocos, 10-15 parts of Chinese yams, 1-3 parts of Chinese wolfberries and 1-3 parts of liquorice roots. Preferentially, the Chinese herb preparation in the form of liquor is prepared from the raw medicinal herbs through the preparation method. The compatibility of the preparation meets the 'monarch, minister, assistant and guide' principle of traditional Chinese medicine, the number of the medicinal herbs is small, the preparation has the advantages of being good in treatment effect, free of toxic and side effects and the like, and the prevention and treatment effect is achieved by dealing with the root cause of diseases and suiting the remedy to the case; besides, the medicinal herbs meeting the 'monarch, minister, assistant and guide' principle in compatibility can prevent and treat vascular hypertension in a multi-way, multi-target-point and multi-level mode. The preparation of the traditional Chinese medicine composition is easy to prepare, low in cost, suitable for being taken for a long time, safe, effective and capable of preventing and treating vascular hypertension and has good application prospects.