Oral medicine composition for treating obesity or vascular hypertension

A technology for hypertension and composition, applied in the field of medicine, can solve problems such as no reports, and achieve the effects of simple production process, reduced incidence, and reduced drug side effects

Inactive Publication Date: 2015-12-16
QINGDAO YUNTIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] There is no report in the prior art about the combined application of orlistat or selistat and dipines

Method used

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  • Oral medicine composition for treating obesity or vascular hypertension
  • Oral medicine composition for treating obesity or vascular hypertension
  • Oral medicine composition for treating obesity or vascular hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1: Prescription of compound orlistat / nifedipine tablet (1000 tablets)

[0020]

[0021]

[0022] Preparation Process:

[0023] (1) Granulation After orlistat, nifedipine, and lactose were sieved and mixed with 80 meshes, they were put into the mixing system together with hydroxypropyl methylcellulose, cross-linked carmellose sodium, and microcrystalline cellulose. Granulator, mixed, evenly added 5% PVP85% ethanol solution for wet granulation, took out the granules and carried out wet granulation with a 20-mesh sieve, after drying, passed through a 20-mesh sieve for granulation, and set aside.

[0024] (2) Compression: Mix the prepared granules with the prescribed amount of magnesium stearate evenly, and compress into tablets to obtain final product.

Embodiment 2

[0025] Embodiment 2: Prescription of compound orlistat / nifedipine tablet (1000 tablets)

[0026]

[0027] Preparation Process:

[0028] (1) Granulation After orlistat, nifedipine, and lactose were sieved and mixed with 80 meshes, they were put into the mixing system together with hydroxypropyl methylcellulose, cross-linked carmellose sodium, and microcrystalline cellulose. Granulator, mixed, evenly added 5% PVP85% ethanol solution for wet granulation, took out the granules and carried out wet granulation with a 20-mesh sieve, after drying, passed through a 20-mesh sieve for granulation, and set aside.

[0029] (2) Compression: Mix the prepared granules with the prescribed amount of magnesium stearate evenly, and compress into tablets to obtain final product.

Embodiment 3

[0030] Embodiment 3: Prescription of compound orlistat / nifedipine tablet (1000 tablets)

[0031]

[0032]

[0033] Preparation Process:

[0034] (1) Granulation After orlistat, nifedipine, and lactose were sieved and mixed with 80 meshes, they were put into the mixing system together with hydroxypropyl methylcellulose, cross-linked carmellose sodium, and microcrystalline cellulose. Granulator, mixed, evenly added 5% PVP85% ethanol solution for wet granulation, took out the granules and carried out wet granulation with a 20-mesh sieve, after drying, passed through a 20-mesh sieve for granulation, and set aside.

[0035] (3) Compression: mix the prepared granules with the prescribed amount of magnesium stearate, and then compress into tablets to obtain final product.

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PUM

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Abstract

The invention discloses an oral medicine composition for treating obesity or vascular hypertension, and belongs to the field of medicine. The medicine composition comprises Orlistat or Cetilista and active ingredients of dipine medicine. In the medicine composition, the use amount of Orlistat or Cetilista and dipine medicine is greatly reduced; particularly, a sustained-release capsule prepared from the medicinal composition can achieve the treatment effect after being taken once a day only, so that the benefit/cost is increased, the patient compliance is improved, and the social value is higher.

Description

technical field [0001] The invention relates to an oral pharmaceutical composition for treating obesity or hypertension, which belongs to the field of medicine. Background technique [0002] "The death of the fattest man in China" sounded the alarm for us. Obesity in today's society does not belong to fat people. As long as the body mass index reaches 24 or more, it is called obesity. It is like a "disease" that entangles the entire human being. Obesity has spread like a plague in developed countries and developing countries with rapid economic development, and the incidence rate has been increasing year by year. Due to the improvement of people's living standards and changes in dietary structure, obesity has become younger. For the treatment of this disease, for the treatment of obesity, the popular weight-loss western medicines in the market are divided into two categories: central nervous system acting drugs and non-central nervous acting drugs. In my country, fenflurami...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4422A61P3/04A61P9/12A61K31/365
Inventor 王传秀
Owner QINGDAO YUNTIAN BIOTECH
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