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35results about How to "Improved benefit/cost ratio" patented technology

Pharmaceutical composition and purpose thereof

The invention belongs to the filed of medicine and discloses a pharmaceutical composition using fimasartan and rosuvastatin or medicinal salt thereof as active components, wherein a mass ratio of rosuvastatin or medicinal salt thereof to fimasartan is 1:0.25-250 and preferably 1:10-100. The pharmaceutical composition containing rosuvastatin medicinal salt thereof and fimasartan has obvious synergism on treating hypertension and complications thereof, low treatment cost, little side-effect and good clinic application prospect.
Owner:LUNAN PHARMA GROUP CORPORATION

Sustained and controlled release preparation for pharmaceutical composition for curing hypertension

The invention provides a sustained and controlled release preparation for a pharmaceutical composition for curing hypertension. The sustained and controlled release preparation composition includes a specific proportion of levamlodipine and angiotensin II receptor blocking pharmacon, wherein the levamlodipine is taken as the sustained and controlled release part and the angiotensin II receptor blocking pharmacon is taken as the common release part. The provided sustained and controlled release preparation enhances the therapeutic effect and reduces the treatment risk of the patients.
Owner:LUNAN PHARMA GROUP CORPORATION

Pharmaceutical composition for treating diabetes and its complications and application thereof

The invention discloses a pharmaceutical composition for treating or preventing diabetes or its complications and an application thereof, and belongs to the medical field. According to the pharmaceutical composition, an insulin sensitizer and bromocriptine or its medicinal salt are used as active pharmaceutical ingredients. When the pharmaceutical composition is used to treat or prevent diabetes or its complications, the medical action modes are complementary. Therefore, the pharmaceutical composition shows remarkable synergism in the hypoglycemic aspect, has low adverse reaction, requires a low price and has a good application prospect.
Owner:LUNAN PHARMA GROUP CORPORATION

Oral pharmaceutical composition for treating or preventing obesity-related hypertension and its application

The invention discloses an oral pharmaceutical composition for treating or preventing obesity-related hypertension and its application and belongs to the field of medicine. The pharmaceutical composition comprises orlistat and lol-suffixed pharmaceutical active ingredients. The usage of orlistat and lol-suffixed pharmaceuticals in the pharmaceutical composition is greatly reduced, thus the risk of pharmaceuticals injuring the human body is reduced. The oral pharmaceutical composition has significant synergistic effect in treating or preventing obesity-related hypertension, can reduce the weight of a patient and the risk of hypertension being complicated by cardiovascular diseases and has higher social value.
Owner:QINGDAO YUNTIAN BIOTECH

Oral medicine composition for treating obesity or vascular hypertension

The invention discloses an oral medicine composition for treating obesity or vascular hypertension, and belongs to the field of medicine. The medicine composition comprises Orlistat or Cetilista and active ingredients of dipine medicine. In the medicine composition, the use amount of Orlistat or Cetilista and dipine medicine is greatly reduced; particularly, a sustained-release capsule prepared from the medicinal composition can achieve the treatment effect after being taken once a day only, so that the benefit / cost is increased, the patient compliance is improved, and the social value is higher.
Owner:QINGDAO YUNTIAN BIOTECH

Medicine for treating diabetes mellitus and application

The invention belongs to the technical field of medicine, and specifically discloses a medicine for treating diabetes and its application. It consists of the following raw materials in terms of weight fraction: 5-10 parts of glibenclamide, 15-20 parts of ginkgo extract, and 5 parts of bromocriptine -10 parts, 10-15 parts of dextrin, 0.1-0.5 parts of malic acid, 1-5 parts of glycyrrhizin, 0.1-0.5 parts of magnesium stearate and 5-10 parts of microcrystalline cellulose. The medicine for treating diabetes of the present invention can effectively solve the problem that type 2 diabetes cannot be effectively controlled by taking common hypoglycemic medicine alone in the prior art, and has the effects of controlling blood sugar, synergistically protecting endothelial cell function, reducing diabetic complications and the like.
Owner:莫玉艳

Medicine composition for treating hypertension

The invention belongs to the field of medicine preparations, which relates to a medicine composition containing the active components of levorotatory amlodipine / amlodipine and losartan. Concretely, the medicine composition is an osmotic pump preparation. The osmotic pump preparation contains main medicines, high molecular substances, a surfactant, an osmotic pressure promoter, an osmosis promotion polymer and auxiliary materials of other conventional preparation tablets and a coating. The medicine composition represents an obvious advantage in the indexes of the pressure relief, the sugar tolerance, the urine content of urine trace albumin, blood leucocyte after stress and the like.
Owner:LUNAN PHARMA GROUP CORPORATION

Pharmaceutical composition and purpose thereof

The invention belongs to the filed of medicine and discloses a pharmaceutical composition using fimasartan and rosuvastatin or medicinal salt thereof as active components, wherein a mass ratio of rosuvastatin or medicinal salt thereof to fimasartan is 1:0.25-250 and preferably 1:10-100. The pharmaceutical composition containing rosuvastatin medicinal salt thereof and fimasartan has obvious synergism on treating hypertension and complications thereof, low treatment cost, little side-effect and good clinic application prospect.
Owner:LUNAN PHARMA GROUP CORPORATION

Pharmaceutical composition for treating chronic cardiac failure and application thereof

The invention discloses a pharmaceutical composition for treating chronic cardiac failure and application thereof. The pharmaceutical composition contains the following two active ingredients: (1), N-methyltyramine or a medicinal salt thereof; (2), any one angiotensin converting enzyme inhibitor. The pharmaceutical composition disclosed by the invention can be used for cooperatively increasing left ventricular systolic pressure, lowering left ventricular end diastolic pressure and improving the sexual function of a rat with chronic cardiac failure, so that the cardiac hypertrophy symptom of a heart failure patient can be reversed, and the effect for treating chronic cardiac failure can be brought into play.
Owner:纪村传

A kind of pharmaceutical composition for treating chronic heart failure and its application

The invention discloses a pharmaceutical composition for treating chronic cardiac failure and application thereof. The pharmaceutical composition contains the following two active ingredients: (1), N-methyltyramine or a medicinal salt thereof; (2), any one angiotensin converting enzyme inhibitor. The pharmaceutical composition disclosed by the invention can be used for cooperatively increasing left ventricular systolic pressure, lowering left ventricular end diastolic pressure and improving the sexual function of a rat with chronic cardiac failure, so that the cardiac hypertrophy symptom of a heart failure patient can be reversed, and the effect for treating chronic cardiac failure can be brought into play.
Owner:纪村传

Hypertension-treating medicine combination

The invention provides a new pharmaceutical composition for treating hypertension, and relates particularly to a composition comprising S-metoprolol and angiotensin converting enzyme inhibitor including enalapril, captopril, lisinopril, perindopril, benazepril and fosinopril, wherein the weight ratio of S-metoprolol to angiotensin converting enzyme inhibitor is (1-35):1, preferably (3-25):1, morepreferably (7.5-18):1. The inventive composition is very important for long-term survival rate of hypertensive patients, and has a positive impact on the prognosis of hypertension for patients.
Owner:LUNAN PHARMA GROUP CORPORATION

Medicine composition containing zafirlukast and statin medicine

The invention provides a medicine composition containing zafirlukast and statin medicine and discloses an application of the medicine composition to the preparation of medicine for treating asthma, which belong to the technical field of medicine. Concretely, the medicine composition contains two medicine active ingredients: zafirlukast and 3-oxhydryl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors according to the mass ratio of 1;(0.01 to 10). In addition, the compound preparation can be made into oral preparations or intestinal tract external preparations.
Owner:刘树芹

Pharmaceutical composition for treating bronchial asthma

The invention belongs to the medical technical field, and relates to a pharmaceutical composition for treating bronchial asthma, in particular to a pharmaceutical composition of Pranlukast and Statins. The pharmaceutical composition contains two active pharmaceutical ingredients such as Zafirlukast and a 3-hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor wherein the ratio of Zafirlukast to 3-hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor is 1:(0.0001-0.01). In addition, the compound preparation in the invention can be made into an oral administration preparation or parenteral administration preparation.
Owner:南通纺都资产管理有限公司

A pharmaceutical composition for treating heart failure with preserved ejection fraction and its application

ActiveCN105748464BLower end diastolic pressureReduce the symptoms of cardiac hypertrophyCardiovascular disorderHeterocyclic compound active ingredientsSide effectPatient compliance
The invention discloses a pharmaceutical composition for treating a heart failure with preserved ejection fraction. The pharmaceutical composition comprises two active components: (1) activity factors of mitochondria acetaldehyde dehydrogenase 2 enzymatic activity; and (2) a nitrate medicine. According to the pharmaceutical composition, left ventricular end diastolic pressure is effectively reduced; the symptom of myocardial hypertrophy of a heart failure patient is improved; the heart failure with preserved ejection fraction is treated; meanwhile, the tolerance of the nitrate medicine when the heart failure with preserved ejection fraction is effectively reduced; and the effective dose of each single medicine is reduced, so that the incidence rate of the side effect of the medicine is relatively low; the treatment cost is also reduced; the benefit / cost ratio of treatment is obviously improved; the compliance of a patient is increased; the living quality is obviously improved.
Owner:SHANDONG UNIV QILU HOSPITAL

Medicine taking prasugrel and Qinlongkusu as active ingredients for treating cerebral infarction

The invention belongs to the field of medicines, and relates to a medicine taking prasugrel and Qinlongkusu as active ingredients for treating cerebral infarction and application thereof. To solve the situation that no ideal medicine for treating cerebral infarction exists in current clinical application, the medicine composition for preventing and treating cerebral infarction is provided, and prasugrel and Qinlongkusu serving as active ingredients of the medicine composition have a remarkable synergistic effect in treatment of cerebral infarction and cerebral ischemia. The medicine is safe to take, and has a good clinical application prospect.
Owner:QINGDAO YUNTIAN BIOTECH

A traditional Chinese medicine composition for treating male erectile dysfunction and its application

The invention relates to a traditional Chinese medicine composition for treating male erectile dysfunction and an application thereof, belonging to the field of medicines. In order to overcome the defects that the existing medicine for treating male erectile dysfunction has the disadvantages of adverse reaction, short action time or slow effectiveness, the invention provides a traditional Chinese medicine composition capable of treating the male erectile dysfunction. The traditional Chinese medicine composition is mainly prepared from the following raw materials in parts by weight: 8-20 parts of cassia twig, 5-15 parts of glossy privet fruit, 5-15 parts of Rehmannia Glutinosa, 3-10 parts of herba epimedii, 10-25 parts of Chinese yam, 5-15 parts of morinda officinalis, 10-20 parts of Mangnolia officinalis, 3-10 parts of fresh ginger, 10-20 parts of prepared tuber of multiflower knotweed, 8-20 parts of astragalus, 5-12 parts of lily, 10-20 parts of poria cocos, 3-10 parts of cistanche, 5-15 parts of angelica sinensis, 3-10 parts of codonopsis pilosula, 3-10 parts of wolfberry, 5-12 parts of spina date seeds, 10-15 parts of scutellaria baicalensis, 10-20 parts of honeysuckle, 3-10 parts of fructus forsythiae, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of the root of Chinese pulsatilla, 5-25 parts of Chinese gall and 10-20 parts of liquorice. The traditional Chinese medicine composition can obviously shorten the erection latency and obviously prolong the ejaculatory latency time and has an excellent effect of treating nervous ED.
Owner:鄄城县人民医院

Compound preparation of quetiapine fumarate and lurasidone

The invention discloses a compound preparation of quetiapine fumarate and lurasidone, which is used for treating schizophrenia. Each preparation unit contains the quetiapine fumarate with the effective dosage of 25-300mg and the lurasidone with the effective dosage of 20-100mg. The dosage of the compound preparation is obviously lower than those of other medicines which are singly used, and the compound preparation has the function of synergy, so that the compound preparation is suitable for severe schizophrenia patients.
Owner:NANJING ZENKOM PHARMA

Drug composition and application thereof

The invention belongs to the field of medicine and relates to a drug composition and application thereof to preparation of a drug for treating encephaledema. Encephaledema is commonly seen in a nervous system disease, and no ideal treatment drug is available clinically now. There are technical problems of an inaccurate treatment effect and a large adverse drug reaction in the prior art. In order to improve the current situation, the drug composition aims at preventing and treating encephaledema and has a good curative effect on encephaledema when used for treating brain traumas, cerebral hemorrhage, cerebral infarction, meningitis, brain tumors and other diseases and used after brain surgery. Compared with the prior art, the drug composition has the advantages of being small in dosage, taking effect quickly and being obvious in effect.
Owner:山东罗欣乐康制药有限公司 +1

A kind of pharmaceutical composition and its application

The invention belongs to the field of medicine, and relates to a pharmaceutical composition and its application in preparing medicine for treating cerebral edema. Cerebral edema is common in neurological diseases, and there is no ideal treatment drug in clinical practice. Moreover, there are technical problems of inaccurate therapeutic effect and large adverse drug reactions in the prior art. In order to solve this situation, the object of the present invention is to provide a pharmaceutical composition for preventing and treating cerebral edema, which can be used in traumatic brain injury, cerebral hemorrhage, When used after cerebral infarction, meningitis, brain tumor and other injuries and brain surgery, it has a good therapeutic effect on cerebral edema, and compared with the prior art, it has the advantages of less dosage, quick effect and obvious effect.
Owner:山东罗欣乐康制药有限公司 +1

Blood glucose reducing drug and use

The invention belongs to the technical field of medicine, and specifically discloses a hypoglycemic drug and its application. It consists of the following raw materials in terms of weight fraction: 5-10 parts of bromocriptine, 15-20 parts of acarbose, and 5-20 parts of kudzu root extract 10 parts, 10-15 parts of xylitol, 0.1-0.5 parts of sorbic acid, 1-5 parts of aspartame, 0.1-0.5 parts of talcum powder and 5-10 parts of dextrin. The hypoglycemic drug of the present invention can effectively solve the problem in the prior art that common hypoglycemic drugs alone cannot effectively control type 2 diabetes, and at the same time have the effects of controlling blood sugar, synergistically protecting endothelial cell function, and reducing diabetic complications.
Owner:黄光友

Medicinal composition containing montelukast and statins medicament

The invention belongs to the technical field of medicaments, provides a medicinal composition containing montelukast and a statins medicament, and discloses application of the medicinal composition to the preparation of a medicament for treating asthma diseases. Specifically, the medicinal composition contains two medicinal active ingredients, i.e., montelukast and a 3-hydroxy-3-methyl glutaryl coenzyme A (HMG-CoA) reductase inhibitor, wherein the mass ratio of the montelukast to the HMG-CoA reductase inhibitor is 1:(0.01-10). Moreover, a compound preparation can be prepared into an oral administration preparation or a parenteral administration preparation.
Owner:JIANGSU LONGCHANG CHEM

Hypertension-treating medicine combination

The invention provides a novel pharmaceutical composition for treating hypertension, and relates particularly to a pharmaceutical composition comprising S-metoprolol and angiotensin II receptor antagonist, wherein the angiotensin II receptor antagonist includes losartan, valsartan, telmisartan, irbesartan or olmesartan; and the weight ratio of S-metoprolol to angiotensin II receptor antagonist is1:(0.1-5), preferably 1:(0.25-2), more preferably 1:(0.5-1.1). The inventive composition is very important for long-term survival rate of hypertensive patients, and has a positive impact on the prognosis of hypertension for patients.
Owner:LUNAN PHARMA GROUP CORPORATION

A kind of pharmaceutical composition for treating hypertension

A pharmaceutical composition for treating hypertension belongs to the field of medicine, in particular to a pharmaceutical composition containing low-dose losartan. The antihypertensive pharmaceutical composition of the present invention contains a pharmaceutically effective amount of levamlodipine or a pharmaceutically acceptable salt thereof and losartan, wherein, levamlodipine is calculated as free base, losartan is calculated as free acid, and levartan is calculated as free acid. The weight ratio of clodipine to losartan is 1:0.2-9. The pharmaceutical composition provided by the present invention enhances the treatment effect and reduces the treatment risk of the patient.
Owner:LUNAN PHARMA GROUP CORPORATION

A kind of pharmaceutical composition and application thereof for treating diabetes and its complications

The invention discloses a pharmaceutical composition for treating or preventing diabetes or its complications and an application thereof, and belongs to the medical field. According to the pharmaceutical composition, an insulin sensitizer and bromocriptine or its medicinal salt are used as active pharmaceutical ingredients. When the pharmaceutical composition is used to treat or prevent diabetes or its complications, the medical action modes are complementary. Therefore, the pharmaceutical composition shows remarkable synergism in the hypoglycemic aspect, has low adverse reaction, requires a low price and has a good application prospect.
Owner:LUNAN PHARMA GROUP CORPORATION
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