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Blood glucose reducing drug and use

A drug and hypoglycemic technology, applied in the field of medicine, can solve problems such as inability to effectively control type 2 diabetes, and achieve the effects of increasing treatment costs, increasing treatment compliance, and reducing incidence.

Inactive Publication Date: 2018-02-23
黄光友
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the above problems, the present invention provides a hypoglycemic drug and its use, which effectively solves the problem that type 2 diabetes cannot be effectively controlled by taking common hypoglycemic drugs alone in the prior art. effects such as complications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A hypoglycemic drug, in parts by weight, comprising the following components:

[0024] 5 parts of bromocriptine, 20 parts of acarbose, 5 parts of kudzu root extract, 15 parts of xylitol, 0.5 part of sorbic acid, 4 parts of aspartame, 0.2 part of talcum powder and 8 parts of dextrin.

[0025] Wherein, Pueraria root extract adopts following method to prepare:

[0026] Step 1: take the dried kudzu root powder, add the sodium hydroxide solution that is 2.5wt% sodium hydroxide solution and the ethanol solution that the equal mass volume fraction is 50% by adding equal mass concentration, heat it to make it boil, extract 3 times, combine the extracts, reclaim wherein ethanol to No alcohol smell, get concentrated solution.

[0027] Step 2: put the concentrated solution on a polyamide column, elute with 97% ethanol for 2 hours, recover the ethanol until it has no alcohol smell, and obtain the kudzu root extract.

[0028] Preparation process: weigh the prescription amount of b...

Embodiment 2

[0030] A hypoglycemic drug, in parts by weight, comprising the following components:

[0031] 10 parts of bromocriptine, 15 parts of acarbose, 10 parts of kudzu root extract, 10 parts of xylitol, 0.3 part of sorbic acid, 5 parts of aspartame, 0.1 part of talcum powder and 10 parts of dextrin.

[0032] Wherein, Pueraria root extract adopts following method to prepare:

[0033] Step 1: take dried kudzu root powder, add the sodium hydroxide solution that is 3.5wt% sodium hydroxide solution and the ethanol solution that the equal mass volume fraction is 50% with equal mass concentration, heat it to make it boil, extract 5 times, combine extracts, reclaim wherein ethanol to No alcohol smell, get concentrated solution.

[0034] Step 2: Put the concentrated solution on a polyamide column, elute with 92% ethanol for 3 hours, recover the ethanol until it has no alcohol smell, and obtain the kudzu root extract.

[0035] Preparation process: weigh the prescription amount of bromocripti...

Embodiment 3

[0037] A hypoglycemic drug, in parts by weight, comprising the following components:

[0038] 8 parts of bromocriptine, 18 parts of acarbose, 8 parts of kudzu root extract, 12 parts of xylitol, 0.3 parts of sorbic acid, 3 parts of aspartame, 0.5 parts of talcum powder and 8 parts of dextrin.

[0039] Wherein, Pueraria root extract adopts following method to prepare:

[0040] Step 1: take dried kudzu root powder, add the sodium hydroxide solution that is 3.5wt% sodium hydroxide solution and the ethanol solution that the equal mass volume fraction is 50% with equal mass concentration, heat it to make it boil, extract 5 times, combine extracts, reclaim wherein ethanol to No alcohol smell, get concentrated solution.

[0041] Step 2: Put the concentrated solution on a polyamide column, elute with 92% ethanol for 2 hours, recover the ethanol until it has no alcohol smell, and obtain the kudzu root extract.

[0042] Preparation process: weigh the prescription amount of bromocriptine,...

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PUM

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Abstract

The invention belongs to the technical field of medicine, and specifically discloses a hypoglycemic drug and its application. It consists of the following raw materials in terms of weight fraction: 5-10 parts of bromocriptine, 15-20 parts of acarbose, and 5-20 parts of kudzu root extract 10 parts, 10-15 parts of xylitol, 0.1-0.5 parts of sorbic acid, 1-5 parts of aspartame, 0.1-0.5 parts of talcum powder and 5-10 parts of dextrin. The hypoglycemic drug of the present invention can effectively solve the problem in the prior art that common hypoglycemic drugs alone cannot effectively control type 2 diabetes, and at the same time have the effects of controlling blood sugar, synergistically protecting endothelial cell function, and reducing diabetic complications.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a hypoglycemic drug and its application. Background technique [0002] Diabetes mellitus (DM) is a group of syndromes caused by environmental and genetic factors. Its basic pathological features are absolute or relative insufficiency of insulin secretion, or peripheral tissue insensitivity to insulin, mainly caused by glucose metabolism disorders, including A systemic disease characterized by disorders of fat and protein metabolism. Diabetes Control and Complications Clinical Trial (DCCT), UK Prospective Diabetes Study (UKPDS) and many other evidence-based medical studies have reached a consensus on the significance of intensified blood sugar control. Reaching the blood sugar target can not only prevent or delay chronic complications of diabetes The occurrence of diabetes will improve the quality of life of patients, and will greatly reduce the medical expenses rela...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/488A61K47/36A61P3/10A61P9/00A61P13/12A61P25/02A61P17/00A61P9/10A61K31/48A61K31/7036
CPCA61K36/488A61K31/48A61K31/7036A61K47/36A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 黄光友
Owner 黄光友
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