Medicament compound containing theophylines and statins
A composition and drug technology, applied in the field of medicine, can solve the problems of insignificant curative effect and large side effects, and achieve the effects of obvious curative effect, reduced side effects, and reduced drug side effects
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Embodiment 1
[0028] The preparation of embodiment 1 tablet
[0029] Pravastatin 6g
[0030] Aminophylline 150g
[0031] Microcrystalline Cellulose 200g
[0032] Sodium carboxymethyl starch 10g
[0034] 8% starch slurry appropriate amount
[0035] Preparation process: Mix pravastatin, aminophylline and auxiliary materials microcrystalline cellulose and sodium carboxymethyl starch evenly, add appropriate amount of starch slurry to make soft material, and pass through a 16-mesh sieve to granulate. The wet granules are dried at 60°C, the dry granules are passed through a 16-mesh sieve for granulation, the fine powder in the dry granules is sifted out, mixed with magnesium stearate, and then mixed with the dry granules, and pressed into tablets to obtain the product.
Embodiment 2
[0036] The preparation of embodiment 2 tablet
[0037] Rosuvastatin 1.5g
[0038] Aminophylline 150g
[0039] Microcrystalline Cellulose 200g
[0040] Sodium carboxymethyl starch 10g
[0042] 8% starch slurry appropriate amount
[0043] Preparation process: Mix pravastatin, aminophylline and auxiliary materials microcrystalline cellulose and sodium carboxymethyl starch evenly, add appropriate amount of starch slurry to make soft material, pass through a 16-mesh sieve to granulate. The wet granules are dried at 60°C, the dry granules are passed through a 16-mesh sieve for granulation, the fine powder in the dry granules is sifted out, mixed with magnesium stearate, and then mixed with the dry granules, and pressed into tablets to obtain the product.
Embodiment 3
[0044] The preparation of embodiment 3 tablet
[0045] Rosuvastatin 75g
[0046] Aminophylline 75g
[0047] Microcrystalline Cellulose 200g
[0048] Sodium carboxymethyl starch 10g
[0050] 8% starch slurry appropriate amount
[0051] Preparation process: Mix pravastatin, aminophylline and auxiliary materials microcrystalline cellulose and sodium carboxymethyl starch evenly, add appropriate amount of starch slurry to make soft material, and pass through a 16-mesh sieve to granulate. Dry the wet granules at 60°C, pass the dry granules through a 16-mesh sieve for granulation, sieve out the fine powder in the dry granules, mix with magnesium stearate, and then mix with the dry granules, and press into tablets to obtain the product.
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