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Medicine for treating diabetes mellitus and application

A diabetes and drug technology, applied in the field of medicine, can solve problems such as inability to effectively control type 2 diabetes, and achieve the effects of increased treatment costs, improved quality of life, and reduced doses

Inactive Publication Date: 2018-02-16
莫玉艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the above problems, the present invention provides a drug for treating diabetes and its use, which effectively solves the problem that type 2 diabetes cannot be effectively controlled by taking commonly used hypoglycemic drugs alone in the prior art. Effects such as diabetes complications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A medicine for treating diabetes, in parts by weight, comprising the following components:

[0024] 5 parts of glibenclamide, 20 parts of ginkgo extract, 5 parts of bromocriptine, 15 parts of dextrin, 0.5 parts of malic acid, 4 parts of glycyrrhizin, 0.2 parts of magnesium stearate and 8 parts of microcrystalline cellulose.

[0025] Wherein, ginkgo extract adopts following method to prepare:

[0026] Step 1: get dry ginkgo powder, add the sodium hydroxide solution that the equal mass concentration is 2.5wt% and the ethanol solution that the equal mass volume fraction is 50%, heat it to make it boil, extract 3 times, combine extracts, reclaim wherein ethanol to No alcohol smell, get concentrated solution.

[0027] Step 2: Put the concentrated solution on a polyamide column, elute with 97% ethanol for 2 hours, recover the ethanol until it has no alcohol smell, and obtain Ginkgo biloba extract.

[0028] Preparation process: Weigh the prescribed amount of glibenclamide, g...

Embodiment 2

[0030] A medicine for treating diabetes, in parts by weight, comprising the following components:

[0031] 10 parts of glibenclamide, 15 parts of ginkgo extract, 10 parts of bromocriptine, 10 parts of dextrin, 0.3 parts of malic acid, 5 parts of glycyrrhizin, 0.1 part of magnesium stearate and 10 parts of microcrystalline cellulose.

[0032] Wherein, ginkgo extract adopts following method to prepare:

[0033] Step 1: get dry ginkgo powder, add the sodium hydroxide solution that the equal mass concentration is 2.5wt% and the ethanol solution that the equal mass volume fraction is 50%, heat it to make it boil, extract 3 times, combine extracts, reclaim wherein ethanol to No alcohol smell, get concentrated solution.

[0034] Step 2: put the concentrated solution on a polyamide column, elute with 97% ethanol for 3 hours, recover the ethanol until it has no alcohol smell, and obtain the ginkgo extract.

[0035] Preparation process: Weigh the prescribed amount of glibenclamide, gi...

Embodiment 3

[0037] A medicine for treating diabetes, in parts by weight, comprising the following components:

[0038]8 parts of glibenclamide, 18 parts of ginkgo extract, 8 parts of bromocriptine, 12 parts of dextrin, 0.3 parts of malic acid, 3 parts of glycyrrhizin, 0.5 parts of magnesium stearate and 8 parts of microcrystalline cellulose.

[0039] Wherein, ginkgo extract adopts following method to prepare:

[0040] Step 1: get dry ginkgo powder, add the sodium hydroxide solution that is 3.5wt% sodium hydroxide solution and the ethanol solution that the equal mass volume fraction is 50% with equal mass concentration, heat to make it boil, extract 4 times, combine extracts, reclaim wherein ethanol to No alcohol smell, get concentrated solution.

[0041] Step 2: Put the concentrated solution on a polyamide column, elute it with 95% ethanol by volume fraction for 3 hours, recover the ethanol until it has no alcohol smell, and obtain the ginkgo biloba extract.

[0042] Preparation process...

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PUM

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Abstract

The invention belongs to the technical field of medicine, and specifically discloses a medicine for treating diabetes and its application. It consists of the following raw materials in terms of weight fraction: 5-10 parts of glibenclamide, 15-20 parts of ginkgo extract, and 5 parts of bromocriptine -10 parts, 10-15 parts of dextrin, 0.1-0.5 parts of malic acid, 1-5 parts of glycyrrhizin, 0.1-0.5 parts of magnesium stearate and 5-10 parts of microcrystalline cellulose. The medicine for treating diabetes of the present invention can effectively solve the problem that type 2 diabetes cannot be effectively controlled by taking common hypoglycemic medicine alone in the prior art, and has the effects of controlling blood sugar, synergistically protecting endothelial cell function, reducing diabetic complications and the like.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a medicine for treating diabetes and its application. Background technique [0002] Diabetes mellitus (DM) is a group of syndromes caused by environmental and genetic factors. Its basic pathological features are absolute or relative insufficiency of insulin secretion, or peripheral tissue insensitivity to insulin, mainly caused by glucose metabolism disorders, including A systemic disease characterized by disorders of fat and protein metabolism. Diabetes Control and Complications Clinical Trial (DCCT), UK Prospective Diabetes Study (UKPDS) and many other evidence-based medical studies have reached a consensus on the significance of intensified blood sugar control. Reaching the blood sugar target can not only prevent or delay chronic complications of diabetes The occurrence of diabetes will improve the quality of life of patients, and will greatly reduce the medical ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/16A61P3/10A61K31/64A61K31/48
CPCA61K31/64A61K31/48A61K36/16A61K2236/333A61K2236/53A61K2236/55A61K2300/00
Inventor 莫玉艳
Owner 莫玉艳
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