The invention relates to the technical field of honeysuckle planting and cultivation, and discloses a high-quality honeysuckle cultivation and large-scale planting method which comprises the following steps: S1, seedling selection; s2, seedling treatment and cultivation; s3, seedling raising and cuttage grafting; s4, seedling growing and planting; s5, seedling culture management; s6, harvesting and processing. According to the method, firstly, seedlings which grow fully and are not damaged are selected during cultivation, so that the survivability of the seedlings can be guaranteed, meanwhile, the seedlings need to be soaked and cleaned and nutrients need to be improved during seedling cultivation, the seedlings can be sterilized and disinfected, growth and development of the seedlings can be promoted, and the survival rate of the seedlings is increased. In addition, in the seedling cultivation process, workers need to record the growth condition of the seedlings in time so that the seedlings can be rapidly treated, during seedling planting and management, soil components need to be treated, the soil excavation distance and depth need to be controlled, and the soil excavation efficiency is improved. Therefore, the survival rate of the seedlings is increased after the seedlings are transplanted.