The invention discloses an interaction method based on a mobile classroom. Operation of a teacher end includes the steps that a teacher end logs into a system, selects a textbook, controls student ends, displays course content on a full screen, takes notes, underlines key points, records and uses an eraser on a page of the book needing to be explained, can add or delete labels on a certain page of the textbook, interacts with the student ends, evaluates students, releases knowledge points and finishes a class. Operation of the student ends includes the steps that the student ends log into the system, select the textbook and display the textbook on full screens, wherein the content displayed by the student ends and the content displayed by the teacher end are consistent; the student ends take notes and conduct other operation; the student ends check evaluation from a teacher after taking participation in interaction; the student ends resolve the knowledge points, and then the class is over. The teacher end can check online conditions of the students in real time and can control textbooks of the students, pages are turned according to the teaching process of the teacher, the concentration degree of the students in the class is improved, the students keep in step with the teacher, learning efficiency of the students is improved, and the teaching system has the teaching activity management function.