Zhuang medicine composition with treatment effect on acute gouty arthritis, Zhuang medicine granules and preparation method of Zhuang medicine composition and Zhuang medicine granules
A technology for acute gout and therapeutic effect, applied in the field of ethnic medicine, can solve problems such as gastrointestinal reactions, skin rashes, and even renal failure, reduce the level of inflammatory cytokines, improve ankle swelling, and promote uric acid excretion. Effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
preparation example Construction
[0028] The present invention also provides a preparation method of the above-mentioned Zhuang medicine composition, which is composed of the following steps: mixing the crude drug of the Zhuang medicine composition with water, soaking for 30 minutes, decocting 3 times, and concentrating the filtrate to a relative The extract with a density of 1.25-1.30 is dried under reduced pressure and then pulverized to obtain the dry cream powder of the Zhuang medicine composition; the mass ratio of the total mass of the crude drug to water is 1:12.
[0029] In the present invention, the decocting time is preferably 40 minutes each time, and the relative density of the extract is preferably the relative density at 60°C.
[0030] The present invention also provides the application of the above-mentioned Zhuang medicine composition or the Zhuang medicine composition prepared by the above-mentioned preparation method in the preparation of Zhuang medicine granules (Tongfeng Li'an Granules, TFLA...
Embodiment 1
[0037] Preparation of Tongfeng Li'an Granules:
[0038] Prescription: swollen knot wind 30g, Polygonum cuspidatum 20g, Honeysuckle vine 20g, Plantain 15g, Fenxia 15g, Xu Changqing 12g, Speranthum 12g, Licorice 6g
[0039] Soak the above eight herbs in 12 times the amount of water for 30 minutes, decoct 3 times for 40 minutes each time, filter, concentrate the filtrate to a thick paste with a relative density of 1.25-1.30 (60°C), dry the paste under reduced pressure, crush it, and pass it for 2 No. sieve to obtain dry paste powder, add dextrin and 95% ethanol according to the ratio of dry paste powder: dextrin: 95% ethanol as 1:1:0.25, mix, granulate, dry, granulate, bag, 15g / bag, that is.
Embodiment 2
[0041] 1. Establishment of animal model of hyperuricemia complicated with acute gouty arthritis and group administration
[0042] Sixty male SD rats were housed in separate cages, fed adaptively for 1 week, and had free access to food and water. Randomly divided into: normal group, model group, positive group and Tongfeng Li'an granule low, medium and high dose groups, 10 in each group. The modeling and administration of each group were carried out at the same time. Tongfeng Li'an granule low, medium and high dose groups were given Tongfeng Li'an granule 4.5, 9, 18g / (kg.d) by intragastric administration respectively; mg / kg), the blank group and the model group were given 10ml / kg pure water by intragastric administration. Each group was administered by intragastric administration continuously for 14 days. Except for the blank group given pure water, the rest of the groups were intragastrically administered oxonate potassium (1.5 g / kg) + adenine (0.05 g / kg) solution 8 hours aft...
PUM
| Property | Measurement | Unit |
|---|---|---|
| particle size (mesh) | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
Login to view more - R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap