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A kind of traditional Chinese medicine composition for treating gout and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating gout and its preparation, can solve problems such as easy rebound, high recurrence rate, and no good cure for gout-related diseases

Active Publication Date: 2020-02-04
AFFILIATED HOSPITAL OF JIANGXI UNIV OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There is currently no good cure for gout-related diseases in western medicine, mainly dietary intervention plus drug control. The principle of treatment for acute gouty arthritis is to control acute inflammation and mainly relieve symptoms such as joint pain and poor mobility
Colchicine, non-steroidal anti-inflammatory drugs and glucocorticoids are often used as medications. These drugs have relatively large toxic and side effects, and have poor effects on some patients. The recurrence rate is high, and it is easy to rebound after drug withdrawal. drug withdrawal

Method used

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  • A kind of traditional Chinese medicine composition for treating gout and preparation method thereof
  • A kind of traditional Chinese medicine composition for treating gout and preparation method thereof
  • A kind of traditional Chinese medicine composition for treating gout and preparation method thereof

Examples

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Effect test

Embodiment 1

[0067] This example discloses a traditional Chinese medicine composition for treating gout, which comprises the following medicinal materials by weight: 24g Guizhi, 24g Radix Paeoniae Alba, 30g Smilax smilax, 30g Rhizoma chinensis, 30g Shengdi, 12g Chonglou, 18g Arrowhead mushroom, 30g Polygonum cuspidatum , 30g Hedyotis diffusa, 24g Lonicerae vine, 30g Achyranthes sichuanensis, 24g Anemarrhena, 30g Cortex Phellodendri. The ratio of the above medicinal materials is obtained through scientific screening.

[0068] In this embodiment, each Chinese medicine composition can be made into a decoction, and each decoction is obtained by boiling the medicinal materials in the above weight ratio.

Embodiment 2

[0070] This example discloses a traditional Chinese medicine composition for treating gout, which comprises the following medicinal materials by weight: 20g Guizhi, 20g Radix Paeoniae Alba, 25g Smilax smilax, 25g Rhizoma chinensis, 25g Shengdi, 9g Chonglou, 15g Arrowhead mushroom, 25g Polygonum cuspidatum .

[0071] In the present embodiment, each Chinese medicine composition can be made into tablet, and its preparation method is as follows:

[0072] S1, weigh each medicinal material according to the above weight, clean it up, cut it off, dry it at room temperature, put it into a wall breaking machine together for 8 minutes, add 50% ethanol solution with a mass ratio of 6 times the mass, and then ultrasonicate for 25 minutes;

[0073] S2, after the ultrasonic wave is completed, use the water bath reflux method to extract for 1.5h. The extraction temperature is 50°C. % of ethanol submerges the dregs, the third time adopts the water bath reflux mode to extract 0.8h, extracts al...

Embodiment 3

[0081] This example discloses a traditional Chinese medicine composition for treating gout: 28g Guizhi, 28g Radix Paeoniae Alba, 35g Smilax Smilax, 35g Rhizome, 35g Rehmannia, 15g Chonglou, 21g Arrowhead Mushroom, 35g Polygonum cuspidatum, 35g Hedyotis diffusa, 28g Honeysuckle vine, 35g Sichuan Achyranthes bidentata, 35g Phellodendron cortex and 28g Zhimu.

[0082] In the present embodiment, each Chinese medicine composition can be made into tablet, and its preparation method is as follows:

[0083] S1, weigh each medicinal material according to the above weight, clean it up, cut it off, dry it at room temperature, put it into a wall breaking machine for 12 minutes, add a 50% ethanol solution with a mass ratio of 10 times the mass, and then ultrasonicate for 35 minutes;

[0084] S2, after the ultrasonic wave is completed, use the water bath reflux method to extract 2.5h, the extraction temperature is 65°C, collect the extract, and add 50% ethanol to immerse the medicinal residue...

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Abstract

The invention relates to the technical field of traditional Chinese medicine formulas, and particularly discloses a traditional Chinese medicine composition for treating gout and a preparation methodthereof. The traditional Chinese medicine composition comprises, by mass, 20-28 parts of cassia twigs, 20-28 parts of radix paeoniae alba, 25-35 parts of poria cocos, 25-35 parts of yam rhizome, 25-35parts of radix rehmanniae recen, 9-15 parts of paris polyphylla, 15-21 parts of edible tulip, 25-35 parts of polygonum cuspidatum, 25-35 parts of hedyotis diffusa, 20-28 parts of honeysuckle stems. The traditional Chinese medicine composition is reasonable in compatibility, has the effects of clearing away heat and dampness, relieving wind and relieving diarrhea, and easing joint movement after all the medicines are used in cooperation, and can remarkably relieve the clinical symptoms of acute gouty arthritis related diseases and improve the quality of life of patients. Radix cyathulae, rhizoma anemarrhenae, cortex phellodendri and the like can be used in cooperation, the radix cyathulae is used as the medicine for introduction, the rhizoma anemarrhenae and cortex phellodendri are used asvarious medicine calamity yin impairment liquid for preventing bitter coldness, and the traditional Chinese medicine composition has the functions of clearing away heat and toxin, clearing away dampness to eliminate turbidity, and easing joint movement and is free of the yin impairment defect after all the medicines are used in cooperation.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for treating gout and a preparation method thereof. Background technique [0002] Gout (Goat) belongs to the category of metabolic rheumatism, which is directly related to purine metabolism disorder and decreased excretion of uric acid. tissue damage. The acute stage mainly manifests as Acute Goat Arthritis, and its clinical manifestations are redness, swelling, heat, pain and dysfunction in the joints (first metatarsophalangeal joint, ankle joint, knee joint, etc.), repeated gout Attacks can easily lead to the formation of tophi, which can lead to joint or kidney damage over time. The small joints of the lower limbs are suddenly red, swollen and painful, and they refuse to press. The local area is hot when touched, and it feels relieved when it is cooled. Accompanied by fever and thirst, restlessness, yellow u...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/90A61K36/898A61K9/20A61K9/14A61K9/48A61P19/06
CPCA61K9/0095A61K9/14A61K9/2059A61K9/48A61K36/21A61K36/355A61K36/54A61K36/65A61K36/704A61K36/71A61K36/748A61K36/756A61K36/804A61K36/8945A61K36/896A61K36/8964A61K36/898A61K36/90A61K2236/333A61K2236/39A61K2236/51A61P19/06A61K2300/00
Inventor 李华南顾兵
Owner AFFILIATED HOSPITAL OF JIANGXI UNIV OF TCM
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