Multifunctional disease animal model manufacturing device based on steam injury

An animal model and technology for making devices, which are applied in medical science, veterinary instruments, veterinary surgery, etc., can solve the problem that the size of scald wounds cannot be adjusted according to needs, the design and prevention research cannot be achieved, and the systemic inflammatory response cannot be accurately grasped and controlled. Syndrome, etc.

Pending Publication Date: 2021-07-27
中国人民解放军联勤保障部队第九二〇医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to study the systemic inflammatory response caused by scald, burn or heat stroke and its medical treatment and drug research, animal models of burn or heat stroke are generally required; special preparation devices are required to replicate the corresponding animal model but the animal model preparation device currently used has the following deficiencies: (1) the function is too single to meet the multiple needs of scald or heat stroke model preparation
The size of the scald wound cannot be adjusted according to the needs, especially the large-scale scald of the whole body cannot be caused or the heat stroke model cannot be prepared, and the pathophysiological process of triggering the systemic inflammatory response syndrome cannot be realized; (2) it is impossible to accurately grasp and control the triggering of the systemic inflammatory response syndrome The degree of symptoms cannot meet the technical requirements for designing prevention and treatment research based on the degree of systemic inflammatory response

Method used

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  • Multifunctional disease animal model manufacturing device based on steam injury
  • Multifunctional disease animal model manufacturing device based on steam injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] refer to Figure 1 to Figure 2 As shown, a multifunctional disease animal model production device based on steam injury is characterized in that it includes: a box body 1, a water storage tank 2, a small suction pump 3, a pipeline 4, a steam generator 5, and a steam pipe 6 , burn mold 7, control unit 8;

[0031] The box body 1 is a cuboid, the left half of the box body 1 is a water storage tank 2, the water storage tank 2 is connected to one end of the delivery pipeline 4, and the other end of the delivery pipeline 4 is connected to the upper surface of the box body 1; the upper surface of the delivery pipeline 4 is close to the water storage tank The 2 ends are connected to the small suction pump 3, the delivery pipe 4 passes through the steam generator 5, and is connected to the steam generator 5; 6 The other end is detachably connected to the burn mold 7; the middle part of the upper surface of the box body 1 is connected to the control part 8;

[0032] The water i...

Embodiment 2

[0037] Based on the structural basis of Example 1, the scald mold 7 can be changed to a fixture that can wrap the whole body of the animal, for making animal models with local scalds of different degrees;

Embodiment 3

[0039] Based on the structural basis of Example 1, the scald mold 7 can be changed into a small chamber where small animals can be placed, which can be used for large-area scald or induced heat stroke models.

[0040] To sum up, the device can set the temperature of the generated water vapor by itself, and is designed with an automatic temperature and humidity monitoring system to ensure that the temperature of the generated water vapor is consistent with the set temperature, and that the generated high temperature and high humidity environment parameters are consistent with the set parameters Keep consistent to avoid excessive scalding of the animal model due to high water vapor temperature or ineffective scalding effect caused by too low temperature, and avoid too high or too low temperature and humidity of the small chamber to achieve the effect of inducing heat stroke.

[0041] The scald mold of the device is designed in a variety of specifications, and the corresponding mo...

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PUM

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Abstract

The invention discloses a multifunctional disease animal model manufacturing device based on steam injury. The device is characterized by comprising a box body, a water storage tank, a small suction pump, a conveying pipeline, a steam generator, a steam pipe, a scald mold and a control part. According to the device, water can be rapidly heated and evaporated into water vapor through the steam generator, the water vapor can directly form a burn model on animal epidermis, and a high-temperature and high-humidity environment can also be formed so that an animal in the environment can form a heat stroke model. The device can accurately set the generation temperature of water vapor and high-temperature and high-humidity environmental parameters, and the most ideal temperature and humidity can be set according to professional requirements. Injury molds with different functional models and sizes are selected according to actual requirements so as to prepare animal models meeting different requirements.

Description

technical field [0001] The invention belongs to the field of animal model making, and in particular relates to a multifunctional disease animal model making device based on steam injury. Background technique [0002] Burns generally refer to heat, including tissue damage caused by hot liquids (water, soup, oil, etc.), steam, high-temperature gas, flames, hot metal liquids or solids (such as molten steel, steel ingots), etc., mainly referring to the skin and / or mucous membranes In severe cases, subcutaneous or / and submucosal tissues may also be injured, such as muscles, bones, joints and even internal organs; scald is tissue damage caused by hot liquid, steam, etc., and is a type of thermal effect injury; heat stroke is Under high temperature and high humidity conditions, heat stress triggers excessive oxidative stress in the body, which is the same as the result of severe burns and scalds. A large number of inflammatory mediators and cytokines are formed. Through the cascade...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01K67/02A61D1/00A61D7/00
CPCA01K67/02A01K2267/03A61D1/00A61D7/00
Inventor 庞荣清王强李自安阮光萍
Owner 中国人民解放军联勤保障部队第九二〇医院
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