Application of recombinant cytokine gene derived protein or fragment thereof

A technology of recombinant cells and derived proteins, which is applied in the field of antiviral research and can solve problems such as the lack of specific treatment methods for diseases
CN113289006APending Publication Date: 2021-08-24GENOVA BIOTECH QINGDAO CO LTD +1
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Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
GENOVA BIOTECH QINGDAO CO LTD
Publication Date
2021-08-24

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Abstract

The invention provides an application of a recombinant cytokine gene-derived protein or a fragment thereof in inhibiting the activity of a coronaviridae virus. The recombinant cytokine gene-derived protein comprises an amino acid sequence SEQ ID NO: 1, or an amino acid sequence having at least 90% identity with the amino acid sequence SEQ ID NO: 1. In addition, the invention also provides application of the recombinant cytokine gene derived protein or the fragment thereof in preparation of drugs for preventing or treating diseases or symptoms related to coronaviridae viruses in subjects. The recombinant cytokine gene derived protein or fragment thereof according to the present invention has enhanced anti-coronaviridae virus activity compared to human interferon [alpha]2b (HuIFN-[alpha]2b).
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Description

technical field

[0001] The present invention belongs to the field of antiviral research, and in particular relates to the use of a recombinant cytokine gene-derived protein or a fragment thereof for inhibiting the activity of Coronaviridae viruses; Use in medicine for a disease or symptom associated with a Coronaviridae virus. Background technique

[0002] Coronavirus is a large virus family, which belongs to the genus Coronavirus of the order Nidovirales, the family Coronaviridae, and the genus Coronavirus in terms of systematic classification. Viruses of the genus Coronavirus are RNA viruses with an envelope and a linear single-stranded positive strand genome. They are a large class of viruses that exist widely in nature. The diameter of coronavirus is about 80-120nm, the 5' end of the genome has a methylated cap structure, and the 3' end has a poly(A) tail. The total length of the genome is about 27-32kb, which is the largest genome among known RNA viruses Virus. Howev...

Claims

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