Self-heating biosensor chip and preparation method thereof, and virus detection method

Abstract

The invention discloses a self-heating biosensor chip and a preparation method thereof and a virus detection method, and belongs to the field of biological detection. The self-heating biosensor chip comprises a substrate, a silicon dioxide layer, a detection unit and a heating electrode. The silicon dioxide layer is formed and covers a supporting surface of the substrate; the detection unit comprises a carbon film and two metal electrodes which are formed on the bearing surface of the silicon dioxide layer respectively, the two metal electrodes are electrically connected with the two ends of the carbon film, the carbon film is configured to be in contact with a sample solution, and the carbon film is provided with a modification surface for modifying biomacromolecules. The heating electrode is formed in the substrate, and the heating surface of the heating electrode abuts against the silicon dioxide layer so as to heat the carbon film through heat conduction. The working voltage of the heating electrode is configured to be 20-35 mV, and the thickness of the silicon dioxide layer between the carbon film and the heating electrode is 150-400 nm. The problem that a biosensor cannot be reused can be solved, the utilization rate is increased, and the detection cost is reduced.

Description

technical field [0001] The present application relates to the field of biological detection, in particular to a self-heating biosensor chip, a preparation method thereof, and a virus detection method. Background technique [0002] Bioelectrical sensors are different from traditional biological detection technologies. They convert the detection of viruses into electrical signals, which is faster and more efficient. However, in most cases, biosensors, such as graphene biosensors, can only be used once, and the reuse rate is low, resulting in high production and detection costs. Contents of the invention [0003] The present application provides a self-heating biosensor chip, a preparation method thereof, and a virus detection method, which can solve the problem that the biosensor cannot be reused. [0004] The embodiment of the application is realized like this: [0005] In a first aspect, the present application example provides a self-heating biosensor chip, which includ...

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Problems solved by technology

[0003] The application provides a self-heating biosensor chip, its preparation method, and a virus detection method, which can solve the problem that biosensors cannot be reused

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