Silver ion-containing chlorhexidine salt compound as well as preparation method and application thereof

A salt compound, chlorhexidine technology, applied in the direction of botanical equipment and methods, applications, biocides, etc., can solve the problems of poor bactericidal and antibacterial effects, short antimicrobial action time, etc.

Active Publication Date: 2021-12-17
洛阳冠银生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide a kind of silver ion-containing chlorhexidine salt compound, which is used to solve the p

Method used

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  • Silver ion-containing chlorhexidine salt compound as well as preparation method and application thereof
  • Silver ion-containing chlorhexidine salt compound as well as preparation method and application thereof
  • Silver ion-containing chlorhexidine salt compound as well as preparation method and application thereof

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Embodiment 1

[0037] The structural formula of the silver ion-containing chlorhexidine salt compound of the present embodiment is that the structural formula is A n (B) mC, wherein A is chlorhexidine, and B is a compound containing group D and group E simultaneously, and C It is a compound containing a carboxyl group, n is 3, m is 0, the group D is -COOH, and the group E is -COOAg; the compound B is obtained by reacting malonic acid and silver nitrate in a molar ratio of 1:1.

Embodiment 2

[0039] The structural formula of the silver ion-containing chlorhexidine salt compound of the present embodiment is that the structural formula is A n (B) mC, wherein A is chlorhexidine, and B is a compound containing group D and group E simultaneously, and C It is a compound containing a carboxyl group, n is 2, m is 0, the group D is -COOH, and the group E is -COOAg; the compound B is obtained by reacting malic acid and silver nitrate in a molar ratio of 1:1.

Embodiment 3

[0041] The structural formula of the silver ion-containing chlorhexidine salt compound of the present embodiment is that the structural formula is A n (B) mC, wherein A is chlorhexidine, and B is a compound containing group D and group E simultaneously, and C It is a compound containing a carboxyl group, n is 1, m is 0, the group D is -COOH, and the group E is -COOAg; the compound B is obtained by reacting citric acid and silver nitrate in a molar ratio of 1:1.

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PUM

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Abstract

The invention relates to a chlorhexidine salt compound containing silver ions as well as a preparation method and application thereof, and belongs to the technical field of antimicrobial agents. According to the chlorhexidine salt compound containing the silver ions, the structural formula of the chlorhexidine salt compound containing the silver ions is A.n(B).mC, wherein A is chlorhexidine, B is a compound containing a group D and a group E at the same time, C is a compound containing carboxyl, n is 1 or 2 or 3 or 4, m is 0 or 1 or 2 or 3, the sum of m and n is less than or equal to 4, the group D is -COOH, and the group E is -COOAg. The chlorhexidine salt compound containing the silver ions is used as an antimicrobial agent, the compound contains a chlorhexidine structure and the silver ions at the same time, the chlorhexidine structure has a rapid sterilization function, and the silver ions have a long-acting antibacterial function; therefore, the chlorhexidine salt compound containing the silver ions has the dual functions of rapid sterilization and long-acting antibiosis.

Description

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Claims

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Application Information

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Owner 洛阳冠银生物科技有限公司
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