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Traditional Chinese medicine composition as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and preparation thereof, can solve the problems of no Chinese patent medicine on the market, different efficacy evaluation standards, etc.

Active Publication Date: 2022-01-25
上海图锋医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, in the field of new drug development of traditional Chinese medicine, there are different evaluation standards for the efficacy of the disease, and the treatment is based on the experience of each doctor. There is no proprietary Chinese medicine on the market.

Method used

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  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1 Chinese medicine compound granule

[0031] Prescription: 30 parts of weeping grass, 15 parts of honeysuckle, 10 parts of red peony, 10 parts of Moutan bark, 5 parts of cooked rhubarb, and 5 parts of licorice.

[0032] The preparation method of this Chinese medicine composition granule:

[0033] Take the above medicinal materials, add water to reflux and extract twice, each time for 1 hour, add 12 times of water for the first time, add 10 times of water for the second time, combine the extracts, filter, and concentrate the filtrate until the ratio of the medicinal materials is 1:1 (relatively Density 1.10~1.15, 60°C), centrifugal filtration, vacuum drying of the filtrate to obtain extract powder, adding dextrin and starch, and obtaining granules by dry granulation.

Embodiment 2

[0034] Embodiment 2 Chinese medicine compound capsule

[0035] Prescription: 60 parts of weeping grass, 30 parts of honeysuckle, 15 parts of red peony, 15 parts of Moutan bark, 10 parts of cooked rhubarb, 10 parts of licorice.

[0036] The preparation method of this Chinese medicine composition capsule:

[0037] Take the above medicinal materials, add water to reflux and extract twice, each time for 1 hour, add 12 times of water for the first time, add 10 times of water for the second time, combine the extracts, filter, and concentrate the filtrate until the ratio of the medicinal materials is 1:1 (relatively Density 1.10~1.15, 60°C), centrifugal filtration, vacuum drying of the filtrate to obtain extract powder, spray drying and granulation, and make capsules.

Embodiment 3

[0038] Embodiment 3 Chinese medicine compound tablet

[0039] Prescription: 60 parts of weeping grass, 30 parts of honeysuckle, 20 parts of red peony, 20 parts of Moutan bark, 10 parts of cooked rhubarb, 10 parts of licorice.

[0040] The preparation method of this Chinese medicine composition tablet:

[0041] Take the above medicinal materials, add water to reflux and extract twice, each time for 1 hour, add 12 times of water for the first time, add 10 times of water for the second time, combine the extracts, filter, and concentrate the filtrate until the ratio of the medicinal materials is 1:1 (relatively Density 1.10~1.15, 60°C), centrifugal filtration, vacuum drying of the filtrate, the obtained extract powder is added with auxiliary materials such as microcrystalline cellulose, and made into tablets.

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Abstract

The invention provides a traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by weight: 1-100 parts of sedum sarmentosum, 1-100 parts of honeysuckles, 1-100 parts of radix paeoniae rubra, 1-100 parts of moutan bark, 1-100 parts of prepared rhubarb and 1-100 parts of liquorice roots. The traditional Chinese medicine composition has an improvement effect on phlebitis vascular injury of marginal vein of rabbit ears, caused by vinorelbine tartrate, has an improvement effect on mouse caudal phlebitis vascular injury caused by fluorouracil, and has an inhibition effect on mouse auricle acute inflammation caused by xylene.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition and its preparation method and application. Background technique [0002] Superficial thrombophlebitis is a common peripheral vascular disease in clinical practice. It is a thrombotic and inflammatory lesion that mostly occurs in the superficial veins of the limbs or trunk. It is often prone to deep vein thrombosis and pulmonary embolism. The clinical manifestations are mostly acute onset. The skin along the superficial veins is red, swollen, burning, and nodules or cords appear, with obvious tenderness and pain. It is more common in the limbs and chest and abdominal wall. After the acute stage, the cords Stomach becomes hard, local skin pigmentation. It belongs to the category of "red vein, green snake venom, evil pulse, yellow loach carbuncle, pulse numbness" in traditional Chinese medicine. Primary disease is a...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K36/708A61K9/16A61K47/36A61P9/14A61P7/02A61P29/00
CPCA61K36/41A61K36/355A61K36/71A61K36/65A61K36/708A61K36/484A61K9/1652A61P9/14A61P7/02A61P29/00A61K2236/331A61K2236/39A61K2236/51A61K2300/00Y02A50/30
Inventor 肖伟张磊刘梅孙丽雪王振中吴伟杨颖博
Owner 上海图锋医药科技有限公司
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