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Plasma or serum exosome separation and extraction device

An extraction device and exosome technology, applied in the field of exosome separation and extraction, can solve the problems of reducing the quality of equipment extraction, reducing the effect of separation and extraction, and the impact of next extraction, so as to achieve increased speed, avoid temperature rise, and improve quality effect

Inactive Publication Date: 2022-02-18
邹帅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the deficiencies of the prior art, the present invention provides a plasma or serum exosome separation and extraction device, which solves the problem that bacteria are prone to appear inside the equipment after a long time of use, which will affect the next extraction, thereby reducing the effect of separation and extraction. It is easy to cause cracks to the internal extract, which reduces the quality of equipment extraction

Method used

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  • Plasma or serum exosome separation and extraction device
  • Plasma or serum exosome separation and extraction device
  • Plasma or serum exosome separation and extraction device

Examples

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Effect test

Embodiment 1

[0043] see Figure 1-6 , the present invention provides a technical solution: a plasma or serum exosome separation and extraction device, comprising a bottom plate 1, the top of the bottom plate 1 is fixedly connected with a device main body 2, and the middle position of the front top of the device body 2 is fixedly connected There is a control panel 3, the top of the back of the main body of the equipment 2 is rotatably connected with a sealed top cover 6, and the main body of the equipment 2 is sealed and closed through the sealed top cover 6, so that the equipment is in a closed space during operation, effectively avoiding external impurities during work work, and the sealing top cover 6 has a glass observation window for observing the internal work of the equipment main body 2, and then when the sealing top cover 6 is closely attached to the equipment main body 2, the inside can still be observed, and the inside of the equipment main body 2 A processing device 4 is fixedly...

Embodiment 2

[0050] see Figure 1-6 , on the basis of Example 1, the present invention provides a technical solution: a method for using a plasma or serum exosome separation and extraction device, step 1: install the device, and connect the temperature detector 5 to the device main body 2 Perform a fixed connection, when the liquid to be tested is placed inside the processing device 4, close the sealing top cover 6 and the equipment main body 2, and connect the equipment main body 2 to the power supply;

[0051] Step 2: Transport the liquid to be tested to the inside of the separation device 45 through the delivery device 46, communicate the cooling device 41 with the piston barrel 43, and communicate the piston barrel 43 with the separation device 45, so that the cold air generated by the cooling device 41 uses the piston The cylinder 43 is transferred to the inside of the separation device 45, and the extraction cylinder 44 is connected to the conveying device 46 in rotation;

[0052] S...

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Abstract

The invention discloses a plasma or serum exosome separation and extraction device. The plasma or serum exosome separation and extraction device comprises a bottom plate, wherein the top of the bottom plate is fixedly connected with a main equipment body, the middle position of the top of the front face of the main equipment body is fixedly connected with a control panel, the top of the back face of the main equipment body is rotationally connected with a sealing top cover, a treatment device is fixedly connected to the bottom of an inner cavity of the main equipment body, and temperature detectors are fixedly connected to the tops of the inner walls of the two sides of the main equipment body. The invention relates to the technical field of exosome separation and extraction. According to the plasma or serum exosome separation and extraction device, the influence of temperature increase in the main equipment body on extraction work is effectively avoided, and a piston cylinder conveys cold air generated by a cooler, so it is guaranteed that the interior of the separation device is in a low-temperature state when extraction work is conducted, the condition that the sufficient time of the extract is shortened due to temperature rise when the separation device works is effectively avoided, and the stress area of a stable chassis is increased.

Description

technical field [0001] The invention relates to the technical field of exosome separation and extraction, in particular to a plasma or serum exosome separation and extraction device. Background technique [0002] Exosomes are small membrane vesicles, which contain complex RNA and proteins. Under normal and pathological conditions, various cells can secrete exosomes, which are mainly derived from the formation of intracellular lysosomal particles. Vesicles are released to the outside of the cell after the fusion of the multivesicular outer membrane and the cell membrane. Under the electron microscope, it can be seen that the exosomes are wrapped by double-layer phospholipid molecules, and the shape is flat or spherical, and some are cup-shaped. [0003] According to the Chinese Patent No. CN112143626B, a device for separating and extracting plasma or serum exosomes improves the efficiency by pressurizing the filter tube, and can also regularly reverse the pressure to ensure t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/34C12M1/38C12M1/12C12M1/00
CPCC12M41/12C12M33/14C12M37/00
Inventor 邹帅
Owner 邹帅
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