A device for fusion of magnetic particle imaging and hyperthermia based on field-free and inertial scanning

Abstract

The invention belongs to the technical field of magnetic particle imaging and hyperthermia fusion, and in particular relates to a magnetic particle imaging and hyperthermia fusion device and method based on inertial scanning without field lines, and aims to solve the lack of image-guided therapy in existing magnetic fluid therapy methods. , Accurate thermal dose setting, non-invasive real-time temperature monitoring and precise positioning, and the design and implementation of classic fieldless line scanning MPI equipment are too complex in structure and control. The device of the present invention includes: a magnet group, an induction coil, a living body bed, a control device, a display device, an image processing device, and a cooling system; the magnet group includes a group of long curved magnet pairs and a cylindrical magnet; the control device is configured to target a target Scanning imaging of living objects and hyperthermia for set sites. The invention realizes the magnetic fluid therapy with the characteristics of image-guided therapy, precise thermal dose setting, non-invasive real-time temperature monitoring and precise positioning, and the device structure and control of the invention are simple.

Description

technical field [0001] The invention belongs to the technical field of magnetic particle imaging and hyperthermia fusion, and in particular relates to a magnetic particle imaging and hyperthermia fusion device and method based on inertial scanning without field lines. Background technique [0002] Magnetic fluid hyperthermia utilizes a suspension of magnetic nanoparticles, administered systemically or locally, combined with an externally applied alternating magnetic field, to ablate target tissue by generating heat through a process called induction. Heat generated at 37°C above mammalian body temperature induces apoptosis and / or enhances the sensitivity of target tissues to other therapies, such as radiotherapy and chemotherapy. While most hyperthermia techniques currently in development are aimed at cancer treatment, hyperthermia is also used to treat restenosis, remove plaque, ablate nerves, and reduce pain by increasing local blood flow. While magnetic fluid hyperthermi...

AI Technical Summary

Problems solved by technology

[0006] In order to solve the above-mentioned problems in the prior art, that is, in order to solve the lack of image-guided treatment, precise thermal dose setting, non-invasive real-time temperature monitoring and precise positioning, and the classical field-line-free scanning MPI equipment in the structure and The problem of high complexity in the design and implementation of control, the present invention proposes a device based on magnetic particle imaging and thermotherapy fusion without field lines and inertial scanning, the device includes: magnet group, induction coil, living bed , control device, display device, image processing device, cooling system;

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