31 results about "Thermal dose" patented technology

An image-guide therapy system comprises a thermal treatment device (e.g., an ultrasound transducer) configured for transmitting a therapeutic energy beam, and The system further comprises an imaging device (e.g., a magnetic resonant imaging (MRI) device) configured for acquiring images of the target tissue mass and the thermal treatment device. The system further comprises a controller configured for controlling thermal dose properties of the thermal treatment device to focus the energy beam on a target tissue mass located in an internal body region of a patient, and a processor configured for tracking respective positions of the thermal treatment device and the target tissue mass in a common coordinate system based on the acquired images. The system may optionally comprise a display configured for displaying the acquired images.

The invention relates to fast planning during surgeries and discloses a method and system for fast planning in an ablation surgery. The system comprises an input device, a calculation device and an output device. The calculation device acquires an actual position of an ablation probe relative to a tumor and a tumor boundary, an ablation range and ablation parameter quantitative relation of the ablation probe and a maximum ablation range parameter of the ablation probe through an input device; ablation parameters of the ablation probe are acquired according to acquired information through the calculation device and outputted through the output device to obtain corrected planning ideas. The problem of probability of incomplete ablation caused by deviation of an actual probe insertion position from a pre-surgical planned probe insertion position in the clinical ablation surgery is solved, accurate control of thermal dose in a focal zone is realized, and ablation effectiveness is guaranteed.

A thermal treatment system including a heat applying element for generating thermal doses for ablating a target mass in a patient, a controller for controlling thermal dose properties of the heat applying element, an imager for providing preliminary images of the target mass and thermal images during the treatment, and a planner for automatically constructing a treatment plan, comprising a series of treatment sites that are each represented by a set of thermal dose properties. The planner automatically constructs the treatment plan based on input information including one or more of a volume of the target mass, a distance from a skin surface of the patient to the target mass, a set of default thermal dose prediction properties, a set of user specified thermal dose prediction properties, physical properties of the heat applying elements, and images provided by the imager. The default thermal dose prediction properties are preferably based on a type of clinical application and include at least one of thermal dose threshold, thermal dose prediction algorithm, maximum allowed energy for each thermal dose, thermal dose duration for each treatment site, cooling time between thermal doses, and electrical properties for the heat applying element. The user specified thermal dose prediction properties preferably include at least one or more of overrides for any default thermal dose prediction properties, treatment site grid density; and thermal dose prediction properties not specified as default thermal dose prediction properties from the group comprised of thermal dose threshold, thermal dose prediction algorithm, maximum allowed energy for each thermal dose, thermal dose duration for each treatment site cooling time between thermal doses, and electrical properties for the heat applying element.

An ultrasound imaging method is provided. The method includes identifying a plurality of locations within a region of interest, delivering a pulse sequence to two or more of the plurality of locations in a determined order, wherein the pulse sequence comprises a pushing pulse, and a tracking pulse, and applying a motion correction sequence to each of the plurality of locations where the pulse sequence is delivered.

A method and system for two and three dimensional mapping of tissue density and / or structural changes from image data and / or spatial reflected or transmitted signal maps, and correlating the maps to changes in collagen density. The method and system includes the steps of: receiving an image or spatial maps of acoustic-derived RF signal data from tissue comprised of multiple pixels, segregating the image into groups of pixels, each group of pixels having characteristics within a defined class, establishing a baseline set of classes corresponding to initial conditions of the imaged / mapped tissue, measuring a differential in the set of classes for a group of pixels, the differential corresponding to a change in pixel values for the group of pixels, correlating said measured differential to a density change for the tissue corresponding to the group of pixels, and overlaying an indication of collagen density over the tissue image or mapped signal responses correlated with thermal dose indicating a change in collagen density for the tissue.

A system for thermal treatment or ablation of tissue includes an ultrasonic thermal ablation probe, an ultrasonic three-dimensional imaging probe that captures an image from radio frequency image data obtained before the radio frequency image data is processed, a control system for multi-axis control of the imaging probe's position, and an ultrasonic feedback mechanism that measures ultrasound echo strain to estimate heat-induced structural changes of an area surrounding the ultrasonic thermal ablation probe, from the image. The ultrasonic thermal ablation probe is either an interstitial ablator inserted into tissue, a natural cavity or a vessel to emit high intensity ultrasound energy to deposit thermal dose, or an external applicator that emits a directional high intensity ultrasound energy to deposit thermal dose via surface contact with tissue. The control system adjusts power levels of the ultrasonic thermal ablation probe based on the estimated heat-induced structural changes.

A thermal treatment system including a heat applying element for generating thermal doses for ablating a target mass in a patient, a controller for controlling thermal dose properties of the heat applying element, an imager for providing preliminary images of the target mass and thermal images during the treatment, and a planner for automatically constructing a treatment plan, comprising a series of treatment sites that are each represented by a set of thermal dose properties. The planner automatically constructs the treatment plan based on input information including one or more of a volume of the target mass, a distance from a skin surface of the patient to the target mass, a set of default thermal dose prediction properties, a set of user specified thermal dose prediction properties, physical properties of the heat applying elements, and images provided by the imager. The default thermal dose prediction properties are preferably based on a type of clinical application and include at least one of thermal dose threshold, thermal dose prediction algorithm, maximum allowed energy for each thermal dose, thermal dose duration for each treatment site, cooling time between thermal doses, and electrical properties for the heat applying element. The user specified thermal dose prediction properties preferably include at least one or more of overrides for any default thermal dose prediction properties, treatment site grid density; and thermal dose prediction properties not specified as default thermal dose prediction properties from the group comprised of thermal dose threshold, thermal dose prediction algorithm, maximum allowed energy for each thermal dose, thermal dose duration for each treatment site cooling time between thermal doses, and electrical properties for the heat applying element.

A subcutaneous fat treatment system and method. An electrode is for application to a patient's epidermis above subcutaneous fat to be treated, There may optionally be a cooling subsystem for cooling the electrode. A sensor such as a microwave radiometer measures the temperature of the subcutaneous fat to be treated. In addition or In the alternative, a subcutaneous fat thickness measurement may be used. A radio frequency source is for applying radio frequency energy to the electrode, A controller subsystem is responsive to the sensor and / or the subcutaneous fat thickness measurement and controls the radio frequency source to determine the thermal dose applied to the subcutaneous fat being treated and automatically adjust the radio frequency energy supplied to the electrode subjecting the subcutaneous fat to a thermal dose of between 0.1 and 10.0.

An air conditioner includes: a cooling unit having a compressor operated at a variable operating frequency to adjust a revolving speed thereof, a condenser, an expansion valve and a cooling coil; and a heating unit for causing the heating medium flowing from the compressor toward the condenser to diverge, and to return to flow into the condenser, through a heating coil and a thermal dose adjusting valve disposed on the downstream side thereof; so as to control a temperature of air by the cooling and heating coils. When an opening manipulated variable of the thermal dose adjusting valve exceeds a first threshold value over a period of time, an operating frequency of the compressor is decreased, and when the opening manipulated variable of the thermal dose adjusting valve falls below a smaller, second threshold value, over the said period of time, the operating frequency of the compressor is increased.

The present invention provides n ultrasonic treatment device (10) for heating a portion of a subject of interest, comprising a ultrasonic irradiation unit (12) for generating high-intensity focused ultrasonic irradiation, whereby a beam path of the ultrasonic irradiation is movable along a trajectory for depositing ultrasonic energy within a target zone (22) of the subject of interest, and a control unit (20) for controlling the ultrasonic irradiation unit (12) to move the beam path of the ultrasonic irradiation along the trajectory and to apply an ultrasonic dose to the target zone (22), wherein the control unit (20) is adapted to receive temperature information of the target zone (22) and to control the ultrasonic irradiation unit (12) based on the received temperature information, and the control unit (20) is adapted to control the ultrasonic irradiation unit (12) based on the temperature of a current (26) and at least one previous direction (28) of the beam path of the ultrasonic irradiation along the trajectory. The invention further provides a corresponding method for ultrasonic treatment and an ultrasonic treatment system, comprising the above ultrasonic treatment device (10) and a diagnostic imaging device for providing temperature information of a target zone (22) of the subject of interest, wherein the control unit (20) of the ultrasonic treatment device (10) is adapted to receive the temperature information from the diagnostic imaging device. By looking at the temperature or a thermal dose distribution along a previous direction of the beam path of the ultrasonic irradiation along the trajectory where the heating has been completed, an improved control of the treatment is achieved. Even if this previous sonication was different to the one currently applied, it represents a good indicator of the tissue and ultrasound system behavior.

The invention belongs to the technical field of magnetic particle imaging and hyperthermia fusion, and in particular relates to a magnetic particle imaging and hyperthermia fusion device and method based on inertial scanning without field lines, and aims to solve the lack of image-guided therapy in existing magnetic fluid therapy methods. , Accurate thermal dose setting, non-invasive real-time temperature monitoring and precise positioning, and the design and implementation of classic fieldless line scanning MPI equipment are too complex in structure and control. The device of the present invention includes: a magnet group, an induction coil, a living body bed, a control device, a display device, an image processing device, and a cooling system; the magnet group includes a group of long curved magnet pairs and a cylindrical magnet; the control device is configured to target a target Scanning imaging of living objects and hyperthermia for set sites. The invention realizes the magnetic fluid therapy with the characteristics of image-guided therapy, precise thermal dose setting, non-invasive real-time temperature monitoring and precise positioning, and the device structure and control of the invention are simple.

A real-time PCR system (1) for detecting gene expression levels includes plural reaction regions (A1), a like plural number of heating portions (16) arranged corresponding to the reaction regions and having heat sources, respectively, an optical unit (12) capable of irradiating exciting light (L1,L2) of a specific wavelength to all of the plural reaction regions (A1), and a like plural number of fluorescence detecting portions (15) arranged corresponding to the reaction regions (A1), respectively. The heating portions (16) are each provided with a temperature detector for detecting a temperature in a vicinity of the corresponding heat source and converting the temperature into an electrical signal and also with a controller for controlling a thermal dose from the corresponding heat source based on a correlation between electrical signals and calorific values of the heat source stored beforehand.

The invention relates to a system for assisting a user in positioning a thermal ablation device (1) on the basis of a planned ablation position. The system comprises an evaluation unit (6) adapted to(i) compute an optimized thermal dose distribution deliverable to the treatment region by means of the device (1) operating at a current position thereof, (ii) determine a path for steering the device(1) from the current position to the planned position and to assign a cost to the determined path, the cost quantifying estimated detrimental effects of steering the device (1) along the computed path, and (iii) present information about the optimized thermal dose distribution and about the cost assigned to the computed path to the user.

The invention belongs to the technical field of magnetic nanoparticle imaging and hyperthermia fusion, and in particular relates to a magnetic particle-based field-free line scanning imaging and field-free point positioning hyperthermia fusion device and method, aiming at solving the lack of images in existing magnetic fluid treatment methods Problems with guided therapy, precise thermal dose setting, non-invasive real-time temperature monitoring and precise localization. The device of the present invention includes: a magnet group, an induction coil, a living body bed, a control device, a display device, an image processing device, and a cooling system; the magnet group includes two sets of long curved magnet pairs and a cylindrical magnet; The two ends of the bending magnet are semi-circular rings, and the semi-circular rings are connected by two arcs constructed with a set curvature; the control device is configured to scan and image the target living object and perform hyperthermia on the set part. The invention realizes the magnetic fluid therapy with the characteristics of image-guided therapy, precise thermal dose setting, non-invasive real-time temperature monitoring and precise positioning.

Adaptive acoustic pressure estimation is provided in medical ultrasound. The responses of tissue of a specific patient at different frequencies (e.g., linear and non-linear responses) are measured. The responses are used to determine the acoustic pressure. The measurement in a specific patient adapts the estimate to the patient. The acoustic pressure for the desired locations is determined in order to set the transmit power to the desired level, such as for contrast agent imaging with high SNR but with limited destruction of the contrast agents or to provide the desired thermal dose the acoustic therapy.

The invention discloses a thermal dose measuring device and a measuring method of a target object in an explosion transient temperature field, and aims to solve the shortcomings of the existing measuring device and method, which are susceptible to electromagnetic interference, complicated in system, needing the assistance of electric measuring equipment, and insufficient in precision . The device consists of a sealed shell, a heating panel, n 3 Root heat-conducting metal pipes, heat-insulating components 4, n 3 Root shape memory alloy spring composition. The shape memory alloy spring is made of one-way shape memory alloy. The invention utilizes the thermal deformation characteristics of the shape memory alloy spring to quantitatively convert the thermal dose parameter in the thermal effect into the spring deformation, and realizes rapid quantitative measurement of the thermal effect of the explosion. The measuring device has the advantages of simple structure, low cost, reusability, strong anti-electromagnetic interference ability, convenient post-processing of results, high measurement accuracy, and can be used for rapid and quantitative measurement of transient temperature fields under different geographical conditions, providing a basis for thermal dose measurement of temperature fields. A new reference option.