7 results about "Thermal dose" patented technology

The invention discloses an in-vitro tissue thermal dose threshold determination method and system based on a thermochromic film, and belongs to the technical field of biomedicine ultrasonic dosimetry. The method comprises the following steps: preparing a thermochromic film with multiple color-changing temperature points, and calibrating a quantitative relationship between the hue and the temperature of the thermochromic film; constructing a sample formed by overlapping an in-vitro tissue, the thin film and a transparent phantom, and placing the sample in a focal region of a high-intensity focused ultrasound system; synchronously carrying out ultrasonic irradiation and film color-changing video acquisition; hue distribution of video frames is converted into temperature distribution through image processing, dynamic accumulation is carried out based on a thermal dose model, and a two-dimensional thermal dose distribution field is reconstructed; and finally, registering the thermal damage area after tissue irradiation with a thermal dose field, and extracting a thermal dose value on the outer side of the damage boundary to calculate a threshold value. The system comprises corresponding ultrasonic generation, sample bearing, image acquisition and control processing units. According to the invention, non-contact, real-time and two-dimensional visual measurement of the heat dose is realized, the system cost is low, and the heat dose threshold can be determined more objectively and accurately.

The invention discloses an ultrasonic temperature measurement method and system based on multi-feature fusion, and belongs to the technical field of medical ultrasonic monitoring. The system comprises a signal acquisition module, a data processing module and an output module. The method comprises the following steps: acquiring an original radio frequency signal acquired by a monitoring probe spatially associated with a focused ultrasound treatment probe; extracting three temperature rise characteristics based on thermal strain, nonlinear sound attenuation and a Nakagami distribution statistics principle in parallel; inputting the multi-parameter characteristics into a pre-trained knowledge distillation physical information neural network model, and directly outputting a predicted temperature value; and the accumulated equivalent heat dose can be calculated according to the predicted temperature to carry out damage judgment. Through multi-parameter complementary fusion and a lightweight intelligent model, accurate and real-time non-intrusive monitoring of the temperature change of a high-temperature treatment interval greater than 50 DEG C is realized, the temperature measurement root mean square error is less than or equal to 0.8 DEG C, the single-frame processing time is less than or equal to 5ms, meanwhile, standardized thermal damage assessment is provided, and the controllability and safety of focused ultrasonic treatment are improved.

The invention discloses a high-safety fat melting method and system and a storage medium. The fat melting method comprises the steps that human body surface data are collected, a three-dimensional surface model is constructed, reflection characteristics, textures, red skin surface temperature and fitting degree data are fused, and an illumination forbidding area is automatically marked; the laser is shaped by the integral rod and the micro lens array and then is projected into a surface illumination light beam by the DMD, and surface illumination dose homogenization is realized according to geometric registration and curvature compensation; a target area is divided into sub-areas, the time sequence effect is staggered, and active cooling is executed between operation. The system adopts an inner-middle-outer three-ring closed loop, the skin surface temperature and the heating rate are limited, the fat layer temperature and the heat dose are estimated according to the skin surface temperature on the basis of a histothermal model, and shading, turn-off and alarm are triggered when abnormity occurs. According to the invention, the risks of mistaken illumination and thermal damage are reduced, the energy delivery consistency is improved, and the method is suitable for medical / household beauty equipment.

This application discloses an ultrasonic thermal strain measurement method and system based on equivalent thermal dose correction, relating to the field of thermotherapy monitoring: acquiring the initial temperature of biological tissue; during the heating process of biological tissue, acquiring ultrasonic echo signal sequences of the target area at preset time intervals; calculating the cumulative thermal strain of the target area at each measurement moment based on the ultrasonic echo signal sequence; coupling and predicting the temperature and equivalent thermal dose at the current moment based on the equivalent thermal dose and temperature at the previous measurement moment, obtaining the predicted values ​​of the temperature and equivalent thermal dose at the current moment; establishing a temperature inversion equation including cumulative thermal strain and equivalent thermal dose, iteratively solving the equation using the predicted value as the initial value, and outputting the corrected temperature value and updated equivalent thermal dose value at the current moment. This application achieves dynamic compensation for the nonlinear changes in acoustic parameters caused by tissue thermal denaturation, thereby improving the temperature measurement accuracy during the ablation stage, expanding the temperature measurement range, and realizing real-time synchronous monitoring of temperature and equivalent thermal dose.

A control system (1) is used to control a charging process of an implantable medical device for a patient. The control system (1) includes a means for determining a temperature (10) of a tissue of a patient; and a control unit (20) configured to determine a cumulative thermal dose of the patient based on the determined temperature. The control unit (20) is configured to continue, after an interruption of the charging process and upon resumption of the charging process, the determination of the cumulative thermal dose based on one or more predefined conditions. The control unit (20) is configured to reset the determined cumulative thermal dose when a time span from interruption is greater than a time limit and / or when a measured temperature is lower than a temperature limit. A method and a corresponding computer program may also provide such control.

The invention provides a tumor ablation integrated system based on a unified space coordinate framework and a working method thereof. According to the system and the working method thereof, a preoperative temperature field and necrosis prediction are generated through multi-physical field simulation, geometric guidance in an operation is realized through augmented reality navigation, a three-dimensional thermal field in the operation is constructed based on CT temperature measurement, and data fusion and dynamic closed loop are realized through a unified coordinate framework, so that full-flow visualization and controllability of a tumor ablation process are realized; the thermal ablation puncture precision, the thermal dose control precision and the information transparency in the operation are improved.