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31 results about "Thermal dose" patented technology

A Thermal dose unit (TDU) is a unit of measurement used in the oil and gas industry to measure exposure to thermal radiation.It is a function of intensity (power per unit area) and exposure time.. 1 TDU = 1 (kW/m 2) 4/3 s.. Results of exposure

Motion compensated image-guided focused ultrasound therapy system

An image-guide therapy system comprises a thermal treatment device (e.g., an ultrasound transducer) configured for transmitting a therapeutic energy beam, and The system further comprises an imaging device (e.g., a magnetic resonant imaging (MRI) device) configured for acquiring images of the target tissue mass and the thermal treatment device. The system further comprises a controller configured for controlling thermal dose properties of the thermal treatment device to focus the energy beam on a target tissue mass located in an internal body region of a patient, and a processor configured for tracking respective positions of the thermal treatment device and the target tissue mass in a common coordinate system based on the acquired images. The system may optionally comprise a display configured for displaying the acquired images.
Owner:INSIGHTEC

Motion compensated image-guided focused ultrasound therapy system

An image-guide therapy system comprises a thermal treatment device (e.g., an ultrasound transducer) configured for transmitting a therapeutic energy beam, and The system further comprises an imaging device (e.g., a magnetic resonant imaging (MRI) device) configured for acquiring images of the target tissue mass and the thermal treatment device. The system further comprises a controller configured for controlling thermal dose properties of the thermal treatment device to focus the energy beam on a target tissue mass located in an internal body region of a patient, and a processor configured for tracking respective positions of the thermal treatment device and the target tissue mass in a common coordinate system based on the acquired images. The system may optionally comprise a display configured for displaying the acquired images.
Owner:INSIGHTEC

Systems, methods and devices for treatment of target tissue

A system for treating a patient comprises an elongate shaft, an expandable reservoir and a fluid delivery assembly. The elongate shaft comprises a distal portion and is constructed and arranged to be introduced into a gastrointestinal lumen. The expandable reservoir is positioned on the elongate shaft distal portion and is constructed and arranged to receive a first fixed amount of ablative fluid and to deliver a first thermal dose of energy to a first portion of target tissue. The fluid delivery assembly is in fluid communication with the expandable reservoir and is constructed and arranged to deliver the first fixed amount of ablative fluid to the expandable reservoir. Devices and methods for treating tissue of a patient are also provided.
Owner:FRACTYL HEALTH INC

Thermal treatment system

A thermal treatment system including a heat applying element for generating thermal doses for ablating a target mass in a patient, a controller for controlling thermal dose properties of the heat applying element, an imager for providing preliminary images of the target mass and thermal images during the treatment, and a planner for automatically constructing a treatment plan, comprising a series of treatment sites that are each represented by a set of thermal dose properties. The planner automatically constructs the treatment plan based on input information including one or more of a volume of the target mass, a distance from a skin surface of the patient to the target mass, a set of default thermal dose prediction properties, a set of user specified thermal dose prediction properties, physical properties of the heat applying elements, and images provided by the imager. The default thermal dose prediction properties are preferably based on a type of clinical application and include at least one of thermal dose threshold, thermal dose prediction algorithm, maximum allowed energy for each thermal dose, thermal dose duration for each treatment site, cooling time between thermal doses, and electrical properties for the heat applying element. The user specified thermal dose prediction properties preferably include at least one or more of overrides for any default thermal dose prediction properties, treatment site grid density; and thermal dose prediction properties not specified as default thermal dose prediction properties from the group comprised of thermal dose threshold, thermal dose prediction algorithm, maximum allowed energy for each thermal dose, thermal dose duration for each treatment site cooling time between thermal doses, and electrical properties for the heat applying element.
Owner:INSIGHTEC

Systems and methods for ultrasound imaging with reduced thermal dose

An ultrasound imaging method is provided. The method includes identifying a plurality of locations within a region of interest, delivering a pulse sequence to two or more of the plurality of locations in a determined order, wherein the pulse sequence comprises a pushing pulse, and a tracking pulse, and applying a motion correction sequence to each of the plurality of locations where the pulse sequence is delivered.
Owner:GENERAL ELECTRIC CO

Adaptive Acoustic Pressure Estimation in Medical Ultrasound

Adaptive acoustic pressure estimation is provided in medical ultrasound. The responses of tissue of a specific patient at different frequencies (e.g., linear and non-linear responses) are measured. The responses are used to determine the acoustic pressure. The measurement in a specific patient adapts the estimate to the patient. The acoustic pressure for the desired locations is determined in order to set the transmit power to the desired level, such as for contrast agent imaging with high SNR but with limited destruction of the contrast agents or to provide the desired thermal dose the acoustic therapy.
Owner:SIEMENS MEDICAL SOLUTIONS USA INC

Microwave ablation treatment planning method based on CT image

The invention discloses a microwave ablation treatment planning method based on a CT image. The method comprises the steps that a medical image sequence of a patient is read and displayed to perform three-dimensional reconstruction; the best needle inserting number and needle inserting route are selected according to a three-dimensional visualized result, wherein the route can avoid important tissues and organs, safety distance is reserved, and the route is the shortest route between a cutaneous needle inserting point and a target region; the optimal input parameters are inversely resolved according to the geometry of a tumor and a preset needle inserting route using an automatic three-dimensional thermal-dose optimization algorithm; the range of a three-dimensional tissue damage field anda temperature field is displayed to evaluate a treatment planning result. By means of the method, a doctor can be assisted in making a reasonable preoperative plan of microwave ablation operation, the clinical executing effect of an operation scheme designed by the doctor using a computer simulation method before the operation is conducted to provide a reliable operation guidance for the doctor,the executing difficulty of the operation is reduced, the operation is safer, and excess damage on the patient is reduced.
Owner:TIANJIN UNIV

Collagen density and structural change measurement and mapping in tissue

A method and system for two and three dimensional mapping of tissue density and / or structural changes from image data and / or spatial reflected or transmitted signal maps, and correlating the maps to changes in collagen density. The method and system includes the steps of: receiving an image or spatial maps of acoustic-derived RF signal data from tissue comprised of multiple pixels, segregating the image into groups of pixels, each group of pixels having characteristics within a defined class, establishing a baseline set of classes corresponding to initial conditions of the imaged / mapped tissue, measuring a differential in the set of classes for a group of pixels, the differential corresponding to a change in pixel values for the group of pixels, correlating said measured differential to a density change for the tissue corresponding to the group of pixels, and overlaying an indication of collagen density over the tissue image or mapped signal responses correlated with thermal dose indicating a change in collagen density for the tissue.
Owner:BURDETTE EVERETTE C +1

Systems and methods for ultrasound imaging with reduced thermal dose

An ultrasound imaging method is provided. The method includes identifying a plurality of locations within a region of interest, delivering a pulse sequence to two or more of the plurality of locations in a determined order, wherein the pulse sequence comprises a pushing pulse, and a tracking pulse, and applying a motion correction sequence to each of the plurality of locations where the pulse sequence is delivered.
Owner:GENERAL ELECTRIC CO

Real time three-dimensional heat-induced echo-strain imaging for monitoring high-intensity acoustic ablation produced by conformal interstitial and external directional ultrasound therapy applicators

A system for thermal treatment or ablation of tissue includes an ultrasonic thermal ablation probe, an ultrasonic three-dimensional imaging probe that captures an image from radio frequency image data obtained before the radio frequency image data is processed, a control system for multi-axis control of the imaging probe's position, and an ultrasonic feedback mechanism that measures ultrasound echo strain to estimate heat-induced structural changes of an area surrounding the ultrasonic thermal ablation probe, from the image. The ultrasonic thermal ablation probe is either an interstitial ablator inserted into tissue, a natural cavity or a vessel to emit high intensity ultrasound energy to deposit thermal dose, or an external applicator that emits a directional high intensity ultrasound energy to deposit thermal dose via surface contact with tissue. The control system adjusts power levels of the ultrasonic thermal ablation probe based on the estimated heat-induced structural changes.
Owner:ACOUSTIC MEDSYST +1

Real time ultrasound thermal dose monitoring system for tumor ablation therapy

An interventional system with real-time ablation thermal dose monitoring includes an interventional tool, an ultrasound transmitter at least one of attached to or integral with the interventional tool, an ultrasound receiver configured to receive ultrasound signals from the ultrasound transmitter after at least one of transmission through or reflection from a region of tissue while under an ablation procedure and to provide detection signals, and a signal processing system configured to communicate with the ultrasound receiver to receive the detection signals and to calculate, based on the detections signals, a thermal dose delivered to the region of tissue in real time during the ablation procedure.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE

Collagen density and structural change measurement and mapping in tissue

A method and system for two and three dimensional mapping of tissue density and / or structural changes from image data and / or spatial reflected or transmitted signal maps, and correlating the maps to changes in collagen density. The method and system includes the steps of: receiving an image or spatial maps of acoustic-derived RF signal data from tissue comprised of multiple pixels, segregating the image into groups of pixels, each group of pixels having characteristics within a defined class, establishing a baseline set of classes corresponding to initial conditions of the imaged / mapped tissue, measuring a differential in the set of classes for a group of pixels, the differential corresponding to a change in pixel values for the group of pixels, correlating said measured differential to a density change for the tissue corresponding to the group of pixels, and overlaying an indication of collagen density over the tissue image or mapped signal responses correlated with thermal dose indicating a change in collagen density for the tissue.
Owner:BURDETTE EVERETTE C +1

Real time three-dimensional heat-induced echo-strain imaging for monitoring high-intensity acoustic ablation produced by conformal interstitial and external directional ultrasound therapy applicators

A system for thermal treatment or ablation of tissue includes an ultrasonic thermal ablation probe, an ultrasonic three-dimensional imaging probe that captures an image from radio frequency image data obtained before the radio frequency image data is processed, a control system for multi-axis control of the imaging probe's position, and an ultrasonic feedback mechanism that measures ultrasound echo strain to estimate heat-induced structural changes of an area surrounding the ultrasonic thermal ablation probe, from the image. The ultrasonic thermal ablation probe is either an interstitial ablator inserted into tissue, a natural cavity or a vessel to emit high intensity ultrasound energy to deposit thermal dose, or an external applicator that emits a directional high intensity ultrasound energy to deposit thermal dose via surface contact with tissue. The control system adjusts power levels of the ultrasonic thermal ablation probe based on the estimated heat-induced structural changes.
Owner:ACOUSTIC MEDSYST +1

Thermal treatment system

A thermal treatment system including a heat applying element for generating thermal doses for ablating a target mass in a patient, a controller for controlling thermal dose properties of the heat applying element, an imager for providing preliminary images of the target mass and thermal images during the treatment, and a planner for automatically constructing a treatment plan, comprising a series of treatment sites that are each represented by a set of thermal dose properties. The planner automatically constructs the treatment plan based on input information including one or more of a volume of the target mass, a distance from a skin surface of the patient to the target mass, a set of default thermal dose prediction properties, a set of user specified thermal dose prediction properties, physical properties of the heat applying elements, and images provided by the imager. The default thermal dose prediction properties are preferably based on a type of clinical application and include at least one of thermal dose threshold, thermal dose prediction algorithm, maximum allowed energy for each thermal dose, thermal dose duration for each treatment site, cooling time between thermal doses, and electrical properties for the heat applying element. The user specified thermal dose prediction properties preferably include at least one or more of overrides for any default thermal dose prediction properties, treatment site grid density; and thermal dose prediction properties not specified as default thermal dose prediction properties from the group comprised of thermal dose threshold, thermal dose prediction algorithm, maximum allowed energy for each thermal dose, thermal dose duration for each treatment site cooling time between thermal doses, and electrical properties for the heat applying element.
Owner:INSIGHTEC

Interpolated three-dimensional thermal dose estimates using magnetic resonance imaging

The invention provides for a medical apparatus (400, 500, 600, 700, 800) comprising a magnetic resonance imaging system (402) for acquiring magnetic resonance thermometry data (442) from a subject (418). The magnetic resonance imaging system comprises a magnet (404) with an imaging zone (408). The medical apparatus further comprises a memory (432) for storing machine executable instructions (460, 462, 464, 466, 10, 660). The medical apparatus further comprises a processor (426) for controlling the medical apparatus, wherein execution of the machine executable instructions causes the processor to: acquire (100, 200, 300) the magnetic resonance thermometry data from multiple slices (421, 421′, 421″) within the imaging zone by controlling the magnetic resonance imaging system; and interpolate (102, 202, 204, 302, 304) a three dimensional thermal dose estimate (444) in accordance with the magnetic resonance thermometry data.
Owner:KONINKLIJKE PHILIPS ELECTRONICS NV

Device and method for measuring thermal dose of target object in explosion transient temperature field

The invention discloses a device and a method for measuring the thermal dose of a target object in an explosion transient temperature field, and aims to overcome the defects that the conventional measuring device and method are susceptible to electromagnetic interference, complex in system, required to be assisted by electrical measurement equipment and insufficient in precision. The device is composed of a sealing shell, a heated panel, n3 heat conduction metal pipes, a heat insulation component 4 and n3 shape memory alloy springs. The shape memory alloy spring is made of one-way shape memory alloy. The thermal dose parameter in the thermal effect is quantitatively converted into the spring deformation by utilizing the thermal deformation characteristic of the shape memory alloy spring, so that rapid quantitative measurement of the explosion thermal effect is realized. The measuring device is simple in structure, low in cost, capable of being repeatedly used, high in anti-electromagnetic interference capacity, convenient in result post-processing and high in measuring precision, can be used for rapid quantitative measurement of the transient temperature field under different regional conditions, and provides a new reference choice for thermal dose measurement of the temperature field.
Owner:NAT UNIV OF DEFENSE TECH

Monopolar RF subcutaneous fat treatment systems and methods

A subcutaneous fat treatment system and method. An electrode is for application to a patient's epidermis above subcutaneous fat to be treated, There may optionally be a cooling subsystem for cooling the electrode. A sensor such as a microwave radiometer measures the temperature of the subcutaneous fat to be treated. In addition or In the alternative, a subcutaneous fat thickness measurement may be used. A radio frequency source is for applying radio frequency energy to the electrode, A controller subsystem is responsive to the sensor and / or the subcutaneous fat thickness measurement and controls the radio frequency source to determine the thermal dose applied to the subcutaneous fat being treated and automatically adjust the radio frequency energy supplied to the electrode subjecting the subcutaneous fat to a thermal dose of between 0.1 and 10.0.
Owner:坎德拉公司

Assisting in positioning a thermal ablation device

PendingUS20210137606A1Efficient executionAccurate positioning the thermal ablation deviceUltrasound therapyMechanical/radiation/invasive therapiesMedicineEngineering
The invention relates to a system for assisting a user in positioning a thermal ablation device (1) on the basis of a planned ablation position. The system comprises an evaluation unit (6) adapted to (i) compute an optimized thermal dose distribution deliverable to the treatment region by means of the device (1) operating at a current position thereof, (ii) determine a path for steering the device (1) from the current position to the planned position and to assign a cost to the determined path, the cost quantifying estimated detrimental effects of steering the device (1) along the computed path, and (iii) present information about the optimized thermal dose distribution and about the cost assigned to the computed path to the user.
Owner:KONINKLJIJKE PHILIPS NV

High-intensity focused ultrasound irradiation

The present invention provides n ultrasonic treatment device (10) for heating a portion of a subject of interest, comprising a ultrasonic irradiation unit (12) for generating high-intensity focused ultrasonic irradiation, whereby a beam path of the ultrasonic irradiation is movable along a trajectory for depositing ultrasonic energy within a target zone (22) of the subject of interest, and a control unit (20) for controlling the ultrasonic irradiation unit (12) to move the beam path of the ultrasonic irradiation along the trajectory and to apply an ultrasonic dose to the target zone (22), wherein the control unit (20) is adapted to receive temperature information of the target zone (22) and to control the ultrasonic irradiation unit (12) based on the received temperature information, and the control unit (20) is adapted to control the ultrasonic irradiation unit (12) based on the temperature of a current (26) and at least one previous direction (28) of the beam path of the ultrasonic irradiation along the trajectory. The invention further provides a corresponding method for ultrasonic treatment and an ultrasonic treatment system, comprising the above ultrasonic treatment device (10) and a diagnostic imaging device for providing temperature information of a target zone (22) of the subject of interest, wherein the control unit (20) of the ultrasonic treatment device (10) is adapted to receive the temperature information from the diagnostic imaging device. By looking at the temperature or a thermal dose distribution along a previous direction of the beam path of the ultrasonic irradiation along the trajectory where the heating has been completed, an improved control of the treatment is achieved. Even if this previous sonication was different to the one currently applied, it represents a good indicator of the tissue and ultrasound system behavior.
Owner:KONINKLJIJKE PHILIPS NV

A device for fusion of magnetic particle imaging and hyperthermia based on field-free and inertial scanning

The invention belongs to the technical field of magnetic particle imaging and hyperthermia fusion, and in particular relates to a magnetic particle imaging and hyperthermia fusion device and method based on inertial scanning without field lines, and aims to solve the lack of image-guided therapy in existing magnetic fluid therapy methods. , Accurate thermal dose setting, non-invasive real-time temperature monitoring and precise positioning, and the design and implementation of classic fieldless line scanning MPI equipment are too complex in structure and control. The device of the present invention includes: a magnet group, an induction coil, a living body bed, a control device, a display device, an image processing device, and a cooling system; the magnet group includes a group of long curved magnet pairs and a cylindrical magnet; the control device is configured to target a target Scanning imaging of living objects and hyperthermia for set sites. The invention realizes the magnetic fluid therapy with the characteristics of image-guided therapy, precise thermal dose setting, non-invasive real-time temperature monitoring and precise positioning, and the device structure and control of the invention are simple.
Owner:BEIHANG UNIV

High-intensity focused ultrasound irradiation

The present invention provides n ultrasonic treatment device (10) for heating a portion of a subject of interest, comprising a ultrasonic irradiation unit (12) for generating high-intensity focused ultrasonic irradiation, whereby a beam path of the ultrasonic irradiation is movable along a trajectory for depositing ultrasonic energy within a target zone (22) of the subject of interest, and a control unit (20) for controlling the ultrasonic irradiation unit (12) to move the beam path of the ultrasonic irradiation along the trajectory and to apply an ultrasonic dose to the target zone (22), wherein the control unit (20) is adapted to receive temperature information of the target zone (22) and to control the ultrasonic irradiation unit (12) based on the received temperature information, and the control unit (20) is adapted to control the ultrasonic irradiation unit (12) based on the temperature of a current (26) and at least one previous direction (28) of the beam path of the ultrasonic irradiation along the trajectory. The invention further provides a corresponding method for ultrasonic treatment and an ultrasonic treatment system, comprising the above ultrasonic treatment device (10) and a diagnostic imaging device for providing temperature information of a target zone (22) of the subject of interest, wherein the control unit (20) of the ultrasonic treatment device (10) is adapted to receive the temperature information from the diagnostic imaging device. By looking at the temperature or a thermal dose distribution along a previous direction of the beam path of the ultrasonic irradiation along the trajectory where the heating has been completed, an improved control of the treatment is achieved. Even if this previous sonication was different to the one currently applied, it represents a good indicator of the tissue and ultrasound system behavior.
Owner:KONINKLJIJKE PHILIPS NV

Assisting in positioning thermal ablation device

The invention relates to a system for assisting a user in positioning a thermal ablation device (1) on the basis of a planned ablation position. The system comprises an evaluation unit (6) adapted to(i) compute an optimized thermal dose distribution deliverable to the treatment region by means of the device (1) operating at a current position thereof, (ii) determine a path for steering the device(1) from the current position to the planned position and to assign a cost to the determined path, the cost quantifying estimated detrimental effects of steering the device (1) along the computed path, and (iii) present information about the optimized thermal dose distribution and about the cost assigned to the computed path to the user.
Owner:KONINKLJIJKE PHILIPS NV

Magnetic particle-based field-free line scan imaging and field-free point localization hyperthermia fusion device

The invention belongs to the technical field of magnetic nanoparticle imaging and hyperthermia fusion, and in particular relates to a magnetic particle-based field-free line scanning imaging and field-free point positioning hyperthermia fusion device and method, aiming at solving the lack of images in existing magnetic fluid treatment methods Problems with guided therapy, precise thermal dose setting, non-invasive real-time temperature monitoring and precise localization. The device of the present invention includes: a magnet group, an induction coil, a living body bed, a control device, a display device, an image processing device, and a cooling system; the magnet group includes two sets of long curved magnet pairs and a cylindrical magnet; The two ends of the bending magnet are semi-circular rings, and the semi-circular rings are connected by two arcs constructed with a set curvature; the control device is configured to scan and image the target living object and perform hyperthermia on the set part. The invention realizes the magnetic fluid therapy with the characteristics of image-guided therapy, precise thermal dose setting, non-invasive real-time temperature monitoring and precise positioning.
Owner:BEIHANG UNIV

Explosion field shock wave power capability and heat effect coupling measurement device and method

The invention discloses a coupling measurement device and method for shock wave acting capacity and heat effect of an explosion field, and aims to realize coupling measurement of shock wave acting capacity and heat effect of the explosion field. The measuring device is composed of a thin-wall metal tube, a one-way shape memory alloy spring, a base, a supporting plate and two sleeves, and the thin-wall metal tube and the one-way shape memory alloy spring are core sensing elements. The shock wave acting capacity is quantitatively converted into thin-walled tube deformation by using the compression deformation characteristic of the thin-walled metal tube, and the thermal dose parameter in the thermal effect is quantitatively converted into spring deformation by using the thermal deformation characteristic of the shape memory alloy spring, so that the shock wave acting and thermal effect coupling rapid quantitative measurement of the explosion field is realized. The one-way shape memory alloy spring is stable in structure after being heated and deformed and can be repeatedly used. The device is simple in structure, free of power supply, convenient to arrange and use, low in use cost, capable of being repeatedly used, simple in measurement method, free of electromagnetic interference and accurate.
Owner:NAT UNIV OF DEFENSE TECH

Adaptive acoustic pressure estimation in medical ultrasound

Adaptive acoustic pressure estimation is provided in medical ultrasound. The responses of tissue of a specific patient at different frequencies (e.g., linear and non-linear responses) are measured. The responses are used to determine the acoustic pressure. The measurement in a specific patient adapts the estimate to the patient. The acoustic pressure for the desired locations is determined in order to set the transmit power to the desired level, such as for contrast agent imaging with high SNR but with limited destruction of the contrast agents or to provide the desired thermal dose the acoustic therapy.
Owner:SIEMENS MEDICAL SOLUTIONS USA INC

Device and method for measuring heat dose of target object in explosion transient temperature field

The invention discloses a thermal dose measuring device and a measuring method of a target object in an explosion transient temperature field, and aims to solve the shortcomings of the existing measuring device and method, which are susceptible to electromagnetic interference, complicated in system, needing the assistance of electric measuring equipment, and insufficient in precision . The device consists of a sealed shell, a heating panel, n 3 Root heat-conducting metal pipes, heat-insulating components 4, n 3 Root shape memory alloy spring composition. The shape memory alloy spring is made of one-way shape memory alloy. The invention utilizes the thermal deformation characteristics of the shape memory alloy spring to quantitatively convert the thermal dose parameter in the thermal effect into the spring deformation, and realizes rapid quantitative measurement of the thermal effect of the explosion. The measuring device has the advantages of simple structure, low cost, reusability, strong anti-electromagnetic interference ability, convenient post-processing of results, high measurement accuracy, and can be used for rapid and quantitative measurement of transient temperature fields under different geographical conditions, providing a basis for thermal dose measurement of temperature fields. A new reference option.
Owner:NAT UNIV OF DEFENSE TECH
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