Nasal secretion sample treatment device

Abstract

The invention discloses a nasal secretion sample treatment device. The nasal secretion sample treatment device comprises a shell, a base, a motor, a partition plate, a top cover, a main shaft and a turntable, the air drying sleeve and the two long-strip-shaped elastic clamping pieces are connected to the rotary disc, the outer end of the air drying sleeve is connected with a necking pipe, and elastic pieces and clamping bosses are arranged on the elastic clamping pieces; the two elastic clamping pieces symmetrically clamp cotton pieces containing nasal secretion samples through the clamping bosses and compress the elastic pieces into the air-drying sleeve, and the cotton pieces are clamped through pressure generated by the elastic pieces on the inner wall of the air-drying sleeve. The device has the characteristics of simple structure, convenience in use, rapidness and high efficiency in sample treatment, guarantee of sampling data accuracy and improvement of inspection work efficiency.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a nasal secretion sample processing device. Background technique [0002] Allergens, also known as allergens, are antigenic substances that cause allergic reactions. The most common allergens include airborne allergens, such as mites, mold, pollen, animal fur, etc., and food allergens, such as milk, eggs, nuts, seafood, etc. . At present, clinically used allergen detection mainly includes two categories: in vivo test, allergen skin prick test, and in vitro test, serum specific allergen (sIgE) detection. The skin prick test is determined by the drug and the patient's own skin. The impact of traces is great, and the full quantitative determination of allergens cannot be achieved. In contrast, serum-specific allergens are more widely used in clinical practice, mainly through the combination of specific allergens on solid-phase or liquid-phase substrates with allergens in p...

AI Technical Summary

Problems solved by technology

[0004] In the prior art, when nasal secretions are tested for specific allergens, the commonly used sampling body is to use an inflatable sponge to collect samples in the patient's nasal cavity. According to the previous data results, it is found that there will be a large amount of mucin in the secretions, and nasal secretion Mucin in nasal secretions cannot be separated from nasal secretions by gradient centrifugation and other methods. When nasal secretions mixed with mucins are tested for specific allergens, the machine will display an error message because the sample is too viscous; When the nasal secretion of mucin is used for cytokine detection, the sample dilution does not form a linear correlation. Due to the influence of mucin, the detection of some cytokines is also lower than the lower limit, which seriously affects the authenticity and reliability of the detection.

After the expansive sponge collects the secretions, it is directly placed in normal saline for soaking. If necessary, the samples can be standardized and can only be tested by the method of protein quantification BCA and then diluted on the machine. According to different testing requirements, the secretions Different solutes are required for the dissolution of different types of sponges. The expansion sponge can only be dissolved with one kind of solute, which has a certain impact on the accuracy of some tests.

In addition, after the expanded sponge is dissolved, it should be stored in a -80-degree refrigerator. Due to the need for testing, it needs to be repeatedly frozen and thawed, and the protein in nasal secretions will be greatly affected by repeated freezing and thawing.

Images