18 results about "Nasal secretion" patented technology

The invention provides a device for collecting a nasal secretion sample. The device includes a sample collection member comprising a material for collecting a predetermined volume of a nasal secretion sample. The device further includes a handle and an elongated support member extending between the handle and the sample collection member and for supporting the sample collection member. The device is adapted for a user holding the handle to locate the sample collection member in contact with tissue at a target location inside the nasal cavity where the sample collection member collects a predetermined volume of a nasal secretion sample.

The utility model provides an aspirator for ear and nose secretion cleaning, which comprises a cabinet, an operating table is fixedly mounted at the top of the cabinet, a first guide cavity and a second guide cavity are respectively arranged in the operating table, a guide chamber and a collection chamber are respectively arranged in the cabinet, and the first guide cavity and the second guide cavity are communicated with each other. A saline water barrel and a collecting assembly are arranged in the collecting chamber, a flow dividing assembly is fixedly installed in the guiding and conveying chamber, the output end of the flow dividing assembly penetrates through the first guiding and conveying cavity and is provided with an injection head in a butt joint mode, and the input end of the flow dividing assembly is connected with the saline water barrel; the input end of the collecting assembly is in butt joint with a recoil assembly. According to the utility model, normal saline in the saline water barrel is extracted through the back flushing assembly, so that the suction operation can be realized, meanwhile, the saline water can be fed into the suction pipeline, not only can sucked foreign matters be discharged in an auxiliary manner, but also the interior of the suction pipe can be continuously flushed, and the inner wall of the suction pipe is prevented from being bonded and blocked.

1. The name of the design product: electric nose aspirator. 2. The use of the design product: the nose aspirator for automatically removing nasal secretions. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view.

This invention relates to the application of a traditional Chinese medicine composition in the preparation of a drug for sinusitis. The composition is characterized by being prepared from ephedra (processed with honey), bitter almond, perilla seed, prepared pinellia, licorice, scutellaria, angelica, belamcanda, coltsfoot flower, mulberry bark, cicada slough, silkworm, and earthworm. The composition of this invention improves sinusitis symptoms, reduces inflammation levels, and regulates the pH of nasal secretions in a sinusitis model prepared by Staphylococcus aureus, suggesting that this traditional Chinese medicine composition has a good therapeutic effect on sinusitis.

The utility model belongs to the technical field of medical auxiliary instruments, particularly relates to a portable quantitative collection device for nasal secretions, and aims to solve the problems that an existing device adopts a negative pressure extraction mode, extraction pressure is not easy to control, nasal mucosa can be damaged when nasal secretions are directly sucked, and bleeding can be accompanied, and the portable quantitative collection device for the nasal secretions comprises a centrifugal tube, a built-in tube is arranged in the centrifugal tube; the utility model has the beneficial effects that the filter paper automatically adsorbs nasal secretions to simulate the natural discharge state of the secretions, so that the secretions at different parts in the nasal cavity can be more comprehensively and uniformly collected without generating any additional pressure impact, thereby protecting the integrity of the mucous membrane of the nasal cavity to the greatest extent, reducing the risk of mucous membrane damage and improving the safety of the nasal cavity. Due to the fact that the nasal cavity cannot be strongly stimulated due to adsorption of the filter paper, discomfort feelings such as pain and soreness caused by negative pressure cannot occur to a patient in the collection process, and the whole collection process is more comfortable.

This invention relates to the field of biomedical technology and proposes a biomarker for reflecting the efficacy of hormone therapy for allergic rhinitis and its application. The biomarker includes one or more combinations of IFNGR1, Furin, and CSF1R. The biomarkers IFNGR1, Furin, and CSF1R of this invention can all differentiate between hormone-sensitive and hormone-insensitive rhinitis. Their expression levels in the nasal secretions of patients with hormone-insensitive allergic rhinitis are significantly lower than those of patients with hormone-sensitive allergic rhinitis, thus reflecting the efficacy of hormone therapy for allergic rhinitis. Furthermore, compared with a single biomarker, the combination of the three biomarkers has better discriminative ability and better efficacy, providing important evidence for subsequent treatment of allergic rhinitis.

The utility model provides a nasal secretion collection device, and belongs to the technical field of nasal secretion collection. Comprising a bag body, a transparent bag is arranged on the side face of the bag body, a partition layer is arranged in the middle of the interior of the bag body, two limiting holes are formed in the partition layer, two sampling pipes are clamped in the limiting holes in a sliding mode, and pipe covers are movably installed on the two sampling pipes in a threaded mode. According to the nasal secretion collection device, through the arrangement of the bag body, the separation layer and the limiting holes, the sampling tubes are limited, and the sampling tubes are prevented from being mixed together to directly collide, so that tube covers of the sampling tubes are prevented from loosening, samples in the sampling tubes are prevented from being polluted, and the accuracy of a detection result is ensured.

The utility model relates to the technical field of secretion extraction, and discloses a newborn oral cavity and nasal cavity secretion extraction device which comprises a shell, a partition plate is fixedly installed on the middle section of the shell, a top cover is connected to the top of the shell in a clamped mode, and a bottom cover is installed at the bottom of the shell in a sliding mode. A storage pipe is arranged in the shell and located below the partition plate in a penetrating mode, the bottom of the storage pipe is in threaded connection with a sealing cover, and a suction pipe is embedded in the side face of the storage pipe. The sealing plug and the intubation tube are firstly taken out from the shell, the intubation tube can be separated from the suction tube, the bottom cover is opened in a sliding mode at the bottom of the shell through the sliding groove and the sliding strip, then the storage tube is drawn out from the two lower protection plates, the sealing cover is spirally opened from the bottom of the storage tube, and secreta in the storage tube can be poured out. Therefore, the purpose of conveniently dismounting and cleaning the storage pipe is achieved, and water can be prevented from entering the shell to damage electronic devices.

The invention discloses application of Der p sIgE and / or Der f sIgE in nasal secretion in preparation of a kit or a detection platform for diagnosing local allergic rhinitis, and relates to the technical field of in vitro diagnosis and immunoassay. The invention relates to application of Der p sIgE and / or Der f sIgE in nasal secretion in preparation of a kit or a detection platform for diagnosing local allergic rhinitis. The invention proposes and verifies that the dust mite sIgE in the nasal secretion can be used as an effective biomarker for diagnosing LAR for the first time, and solves the technical problem of difficulty in typing serum sIgE negative rhinitis patients clinically. Detection can be completed only by collecting nasal secretions, operation is easy and convenient, safety is high, and clinical popularization is easy. According to the method, diagnosis is objective and accurate, a diagnosis critical value is scientifically established through research on healthy people, a quantitative objective diagnosis standard is provided, it is verified through the cell factor level that the diagnosis result is highly consistent with the intrinsic biological mechanism of allergic inflammation, and the accuracy is high.

1. Name of the product in this design: Nose hair scraper. 2. Purpose of this design: For cleaning nasal hairs and nasal secretions. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

1. The name of the design product: nose wax stick. 2. The use of the design product: for cleaning the nose hair and nasal secretions. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view 1.

The utility model relates to the technical field of tracheostomy patient collecting devices, in particular to a mouth and nose secretion collecting device for tracheostomy patients with dysphagia, which is characterized in that two nasal liquid tubes are mounted at the bottom of one side of a protective mask in a penetrating manner, a nose support is mounted on the outer side of the top end of each nasal liquid tube, and a collecting piece is arranged at the top of each nasal liquid tube; a mounting plate is mounted on one side in the protective mask, rotating parts are mounted on two sides of the saliva tube, the nose support extends into the nasal cavity, and then the nasal tube is matched to drive the blocking ball to move into the nose support, so that the diameter of the nose support is expanded, supporting force is provided for the interior of the nasal cavity, liquid in the nasal cavity can flow out more smoothly, and the safety of the nasal cavity is improved. Oral secretions flow into the other side of the liquid collecting bottle along the saliva tube, the oral secretions of a patient can be conveniently collected, the cleaning process is simpler and more convenient, and meanwhile, the saliva tube and the expansion sponge are made of soft materials, so that the patient does not have foreign body sensation in the process of wearing and using the device.

The application discloses a nasal secretion biomarker composition for diagnosing type 2 chronic rhinosinusitis with nasal polyps and application thereof, relates to the technical field of biological medicine, and the nasal secretion biomarker composition comprises glial cell-derived neurotrophic factor, cystatin 5, transforming growth factor beta 1 and monocyte chemoattractant protein 4. When the nasal secretion biomarker composition is used for diagnosing CRSwNP intrinsic type, nasal secretion is used as a detection sample, polyp biopsy is not needed, the nasal secretion biomarker composition is non-invasive, simple, convenient, has high sensitivity and specificity, can classify CRSwNP patients before operation without damaging mucosa, can predict the disease intrinsic type of the CRSwNP patient in advance and accurately, and is an ideal non-invasive method.

The invention relates to the field of biological medicine, and particularly provides application of LCN2 as a biomarker of non-eosinophilic chronic disease nasosinusitis with nasal polyp. The LCN2 provided by the invention is derived from nasal secretion, and by detecting a nasal secretion sample which is easy to collect, the wound, pain and potential complication risk caused by traditional nasal polyp tissue biopsy are completely avoided, and the detection compliance and acceptability of a patient are remarkably improved. The collection process of the nasal secretions is simple, and the technical requirements on operators are not high. The LCN2 detection method is relatively mature, is controllable in cost, is convenient to popularize and apply in medical institutions at all levels, and is suitable for screening large-scale crowds. The LCN2 level in nasal secretions has high sensitivity and specificity for distinguishing neCRSwNP from eCRSwNP and healthy people, and the ROC area under the curve (AUC) of the LCN2 level shows good diagnostic value.

The present invention relates to an in vitro method for diagnosing or predicting a degenerative disease of the nervous system in a subject, said method comprising performing A / T / N classification in a sample of nasal secretions obtained from said subject. The A / T / N classification can then be used, but not limited to, for the diagnosis of Alzheimer's disease (AD), for the diagnosis of SNAP, or for the exclusion of AD.

The utility model belongs to the technical field of collecting devices, and particularly relates to an animal mouth and nose secretion automatic collecting device which comprises a base, a negative pressure aspirator, a sealing cover, a connecting pipe and a collector, a connecting rod is vertically installed at the top end of the base, a supporting rod is movably connected to the top end of the connecting rod, and a fixing block is installed at the top end of the supporting rod. Through the synergistic effect of the connecting rod, the supporting rod and the adjusting sleeve, flexible adjustment of the sealing cover is achieved, the connecting pipe can be dragged to move along with the sealing cover, and therefore using of the sealing cover is not limited by the connecting pipe any more. Therefore, the sealing cover and the collecting tube can be conveniently matched for use. Besides, through ingenious cooperation of a clamping block and a bidirectional threaded rod, the collecting pipe can be conveniently fixed to the top end of the base, and it is ensured that collecting pipes of different sizes can be stably fixed through the design.

The present application relates to the technical field of nasal negative pressure suction, in particular to a nasal negative pressure suction tube convenient for extracting secretions, comprising a connecting frame, a top frame is fixedly connected to the top end of the connecting frame, a mounting frame is fixedly connected to the back of the connecting frame, a handle groove is formed in the side surface of the mounting frame, a storage tank is movably connected to the inside of the mounting frame, a negative pressure pump is arranged on the back of the top frame, suction tubes are fixedly connected to the two ends of the negative pressure pump, and an air exhaust frame is fixedly connected to the center of the surface of the connecting frame. The connecting frame, the top frame, the mounting frame, the storage tank, the rotating seat, the second docking frame, the docking ring and the docking seat can realize efficient and stable suction operation of the nasal secretions of the patient. In actual use, the staff first assembles the equipment to be used, and then the staff can use tweezers to stably insert the negative pressure tube into the patient's nasal cavity from the patient's nostrils.