Medicine for treating amnesia and dementia
A technology for amnesia and dementia, applied in drug combinations, pharmaceutical formulas, plant raw materials, etc., can solve the problems of large adverse reactions, poor curative effect, unsuitable for long-term use, etc., achieve less adverse reactions, promote the growth and development of nerve cells, improve The effect of memory impairment
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Embodiment 1
[0020] Embodiment one, the formula of this example is as shown in table 1:
[0021] name
parts by weight
sea snake
10
25
40
sea cucumber
7.5
18.75
30
polygala
10
22.5
35
calamus
10
22.5
35
[0022] The production method of making medicine of the present invention with above-mentioned component is:
[0023] (1) First take 1 / 4 of the sea snake, grind it to coarse powder and use it separately;
[0024] (2) The remaining 3 / 4 amount of sea snake and sea cucumber is crushed into the coarsest powder, pre-soaked with water and decocted 3 times, or decocted 2 times after enzymatic hydrolysis, combined decoction, filtered, and the filtrate is concentrated to a relative density of 1.05- 1.20 (80 ℃) clear paste;
[0025] (3) Volatile oil is extracted after presoaking of Acorus calamus, and the distilled medicinal liquid is collected in another device. The dregs and...
Embodiment 2
[0029] Embodiment two, the formula of this example is as shown in table 2:
[0030] name
[0031] The production method is the same as the above example, and will not be repeated.
[0032] After the present invention is administered orally to animals, the Y-maze method and the platform jumping method are used to study the experimental research, which shows that it can obviously resist the memory acquisition disorder of animals caused by scosunculate, the memory consolidation disorder of animals caused by sodium nitrite and the 40% The impairment of animal memory reproduction caused by ethanol also has a certain promoting effect on the memory function of normal animals, see Table 3-6 for details.
[0033] group
[0034] * p** p<0.01 compared with blank control group
[0035] group
[0036] N=18, ##p<0.01 compared with blank control group
[0037] * p** p<0.01 compared with the model group
[0038] group
[0039] (continued from the t...
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