Combined bacterin for treating allergic disease and preparation method

An allergy, vaccine technology, used in allergic diseases, sensory diseases, respiratory diseases, etc.

An allergy, vaccine technology, used in allergic diseases, sensory diseases, respiratory diseases, etc.

CN1247261CInactive Publication Date: 2006-03-29天津市长征医院
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Experimental program
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Embodiment Construction

[0020] Purchase Streptococcus pneumoniae, Streptococcus alpha-hemolytic, Streptococcus beta-hemolytic, Staphylococcus aureus, Staphylococcus epidermidis, Neisseria catarrhalis, Haemophilus influenzae, A aeruginosa from National Culture Collection Bacteria, Proteus, Escherichia coli, Klebsiella pneumoniae, Candida albicans standard strains each 2.

[0021] One of them was dissolved in 0.5ml sterilized physiological saline, inoculated in the corresponding culture medium, and cultured by streaking in regular divisions, and cultured at 37°C for 24-48 hours. Among them: Staphylococcus aureus, Staphylococcus epidermidis, A. aeruginosa, Proteus, Neisseria catarrhalis, and Klebsiella pneumoniae were inoculated in ordinary medium; A-hemolytic streptococcus, B-hemolytic Streptococcus was inoculated in fresh blood medium; Escherichia coli was inoculated in SS medium; Candida albicans was inoculated in Sabouraud medium; Bacillus influenzae was inoculated in chocolate medium; Streptococcus...

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Abstract

The present invention relates to a combined bacterial vaccine for curing allergic diseases of allergic rhinitis, allergic conjunctivitis, various bronchitis and asthma and deafness resulted from medicine with good therapeutic effect. Said combined bacterial vaccine is formed from diplococcus pneumoniae, alpha-hemolytic streptococcus, beta-hemolytic streptococcus, staphylococuus aureus, staphylococcus epidermidis and others.

Description

technical field [0001] The invention relates to a pharmaceutical preparation containing bacteria, in particular to a combined bacterial vaccine for treating allergic diseases and a preparation method thereof. technical background [0002] Allergic diseases are more common in dermatology, respiratory medicine, and ENT. The clinical manifestations are various diseases such as atopic dermatitis, eczema, allergic rhinitis and asthma, accounting for about 20-50% of outpatient visits in various departments. Modern immunomedicine believes that the main mechanism of allergic diseases is: genetic factors as the background, foreign antigen-induced, Th2 cell-mediated I-VI allergy. There are many clinical treatment methods, mainly antihistamine drug treatment. As for the desensitization treatment for foreign antigens, due to the difficulty in finding allergens and the limitation of specific antigen preparation, clinical use is rare. [0003] It has been reported in foreign literature ...

Claims

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Application Information

Patent Timeline
29 Mar 2006
Publication
CN1247261C
IPC
A61K39/02; A61P37/08; A61P11/06; A61P11/00; A61P27/16
Inventors
张玉环; 张理涛