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Coating film preparation for dispelling swelling and relieving pain and its preparation method

A technology for reducing swelling, relieving pain and coating film agent, which can be applied in the directions of non-central analgesics, anti-inflammatory agents, pharmaceutical formulations, etc. The effect of easy control of hygienic conditions, accurate dosage and simple production operation

Active Publication Date: 2007-05-16
广西壮族自治区花红药业集团股份公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Rheumatism causes inconvenience to patients in daily life and work, and has a high disability rate, which has a great impact on the physiology and psychology of the patients themselves, and forms a huge burden on the society
Although there are many traditional Chinese medicine preparations for the treatment of bruises and rheumatic bone pain clinically, the clinical effects are not very satisfactory, and there are certain discomfort and side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0126] API prescription:

[0127] Woody Fragrance 47g Fangfeng 47g Nepeta 47g Asarum 47g

[0128] Wujiapi 47g Guizhi 47g Achyranthes bidentata 47g Chuanxiong 47g

[0129] Xu Changqing 47g Angelica dahurica 70g Curcuma 47g Red Eucommia 70g

[0130] Big Luo Umbrella 100g Xiao Luo Umbrella 70g Double-faced Needle 100g Huangteng 95g

[0131] Gardenia 100g Triangle 70g Agarwood 32.5g Camphor 55g

[0132] Menthol 55g

[0133] Preparation method of active ingredient:

[0134] The above twenty-one flavors, except camphor and menthol, the other nineteen flavors such as woody fragrance are ground into 20 orders, according to the percolation method (Chinese Pharmacopoeia 2000 edition one appendix 10) under the liquid extract and extract item, use 53% ethanol was used as solvent, after soaking for 28 hours, slowly percolating at a speed of 3ml per minute, collecting 5000g of filtrate, concentrated under reduced pressure to a relative density of 1.3 (80°C) extract, taking camphor, men...

Embodiment 2

[0137] API prescription:

[0138] Woody Fragrance 100g Fangfeng 100g Nepeta 100g Asarum 100g

[0139] Wujiapi 100g Guizhi 100g Achyranthes bidentata 100g Chuanxiong 100g

[0140] Xu Changqing 100g Angelica dahurica 70g Curcuma 100g Red Eucommia 70g

[0141] Big Luo Umbrella 250g Xiao Luo Umbrella 150g Double-faced Needle 250g Huangteng 200g

[0142] Gardenia 250g Triangle 150g Agarwood 80g Camphor 80g

[0143] Menthol 80g

[0144] The preparation method is the same as in Example 1.

[0145] 300g of the extracted active ingredient was added to 40g of polyvinyl butyral, and stirred while adding until it was completely dissolved, and then 70% ethanol was added to 6000g to obtain the product. Sealed in vials, 10g per bottle. Active ingredient 0.5g.

Embodiment 3

[0147] API prescription:

[0148] Woody Fragrance 90g Fangfeng 90g Nepeta 90g Asarum 90g

[0149] Wujiapi 90g Guizhi 90g Achyranthes bidentata 90g Chuanxiong 90g

[0150] Xu Changqing 90g Angelica dahurica 70g Curcuma 80g Red Eucommia 70g

[0151] Big Luo Umbrella 200g Xiao Luo Umbrella 140g Double-faced Needle 200g Huangteng 200g

[0152] Gardenia 220g Triangle 150g Agarwood 80g Camphor 80g

[0153] Menthol 80g

[0154] The preparation method is the same as in Example 1.

[0155] Add appropriate amount of 70% ethanol to 300g of the extracted active ingredient, stir well, then slowly add 38g of collodion, stir as you add, divide and pack quickly after stirring, seal in vials, 10g per bottle. Active ingredient 0.48g.

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PUM

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Abstract

The invention discloses a coating film preparation for dispelling swelling and relieving pain and its preparation method, which comprises the extracts of 21 Chinese medicinal herbs including banksia rose, ledebouriella root, Schizonepeta tenuifolia, asaryl, cortex acanthopanacis, cassia twig, achyranthes and cyathula root, Ligusticum wallichii, panicled swallowwort root, dahurian angelica root, zedoary, eucommia bark, Ardisia crenata, Ardisia crenata Sims, shiny pricklyash, fibraurea stem, cape jasmine, burred tuber, linaloe, camphor, menthol, right amount of film forming material and organic solvent.

Description

technical field [0001] The invention relates to a Chinese patent medicine preparation for treating bruises, sprains, rheumatic bone pain, unknown swelling and poisoning, and a preparation method thereof, in particular to a swelling-relieving and pain-relieving coating agent using Chinese herbal medicine as a raw material and a preparation method thereof. Background technique [0002] According to "my country's Rheumatism Four Diseases Epidemiological Sampling Survey", the incidence rate of rheumatism in the natural population in China is 14%, and the special industry (textile, iron and steel machinery, chemical industry, mining oil, port, army) is as high as 23.1%; the rheumatism four diseases The main affected population is between 40 and 60 years old; at present, it is estimated that 182 million people suffer from rheumatism in my country, and 94.64 million people are over 40 years old. Rheumatism causes inconvenient movement in daily life and work to patients, and has a hi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/906A61K36/744A61K36/59A61K36/54A61K36/285A61K36/236A61K36/185A61K9/00A61P29/00
Inventor 韦飞燕
Owner 广西壮族自治区花红药业集团股份公司
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