Stable non-aqueous single phase viscons vehicles and formulations utilizing such vehicles
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- INTARCIA THERAPEUTICS INC
- Publication Date
- 2002-03-13
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
field of invention
[0001] The present invention relates to stable non-aqueous single-phase adhesive biocompatible carriers that can suspend beneficial substances and uniformly disperse said substances at low flow rates, and in particular relate to beneficial substances in a stable non-aqueous single-phase biocompatible viscosity A stable homogeneously mixed formulation in a carrier. references
[0002] The numbers in square brackets ([ ]) in relevant parts of this specification refer to the following documents. 1. Wang, et al. J. Parenteral Sci. Tech., 42: S4-S26 (1988). 2. Desai, et al. J. Am. Chem. Soc., 116:9420-9422 (1994). 3. Chang, et al. Pharm. Tech., pp. 80-84 (June, 1996). 4. Manning, et al. Pharm. Res., 6:903-918 (1989). 5. Hageman, Drug Dev. Ind. Pharm, 14:2047-2070 (1988). 6. Bell,. Biopolymers, 35:201-209 (1995) 7. Zhang, et al. Pharm. Res., 12:1447-1452 (1995). 8. PCT Publication No. 98 / 001589. PCT Publication No. 981625010. Knepp, et al. Pharm. Res., 15(7...