Antiviral drug containing silverweed cinquefoil essence and its prepn

A technology of antiviral drug and pterogenin, which is applied in antiviral agents, medical preparations containing active ingredients, and pharmaceutical formulas, etc.

Inactive Publication Date: 2002-10-16
THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are no literature reports on the systematic research on anti-virus and anti-hepatitis pharmacology and pharmacodynamics, and the systematic research on the effective parts and active ingredients of Zeraria antiviral activity

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0126] Example 1 Phagenin 200mg microcrystalline cellulose 100mg starch 30mg stearic acid 2mg simple syrup 10mg

[0127] Preparation method: Mix pterogenin and microcrystalline cellulose for 25 minutes, add starch and simple syrup, mix for 10 minutes, add stearic acid before tableting, and use 13 / 32 hour standard punch or flat press to punch tablets.

Embodiment 2

[0128] Example 2 Phagenin 250mg microcrystalline cellulose 60mg starch 30mg stearic acid 5mg powdered sugar 15mg

[0129] Preparation method: Mix microcrystalline cellulose, starch and powdered sugar for 20 minutes, add peckin and stearic acid, granulate with 95% ethanol, dry under reduced pressure at 60°C, and compress into tablets under the same conditions as Example 1.

Embodiment 3

[0130] Example 3 Phagenin 300mg microcrystalline cellulose 60mg starch 30mg stearic acid 5mg starch slurry 20mg

[0131] Preparation method: Mix peckin, microcrystalline cellulose, starch and starch slurry for 30 minutes, add stearic acid, granulate with 80% ethanol, dry under normal pressure at 70°C, and compress into tablets under the same conditions as in Example 1.

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PUM

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Abstract

The present invention belongs to the field of natural medicine technology and is especially one kind of antiviral drug containing silverweed cinquefoil essence, Pharmacodynamics research shows that the drug of the present invention has inhibition effect to HbsAg and HbeAg, obvious inhibiting effect on hepatitis B virus and the function of protecting liver cell and promoting repair of damaged liver cell and may become one prospective hepatitis B virus resisting medicine.

Description

technical field [0001] The invention belongs to the technical field of natural medicines. In particular, it relates to an antiviral drug containing pterogenin extracted from Bracken genus and a preparation method thereof. Background technique [0002] At present, there are only a few domestic and foreign reports on the research on the pharmacognosy of Bracken phytochemicals, the research on the phytochemical components of Bracken Bracken, and the research on plateau hypoxia tolerance of Bracken Bracken raw materials and other traditional Chinese medicine formulas. . There are no literature reports on the systematic research on anti-virus and anti-hepatitis pharmacology and pharmacodynamics, and the systematic research on the active parts and active ingredients of Zerina japonica. So far, the systematic research on the anti-hepatitis and anti-virus of the active part of the new drug Zernenna japonica, the clinical trials of small samples, and the research on the anti-viral ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/19A61P31/12
Inventor 蔡光明袁海龙赵燕玲张新全陈新华汤春玲
Owner THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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