Combined bacterin for treating allergic disease and preparation method

An allergy and bacterin technology, applied in the direction of allergic diseases, sensory diseases, respiratory diseases, etc.

Inactive Publication Date: 2004-03-24
天津市长征医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few reports on the use of vaccines for the prevention and treatment of allergic diseases

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0021] Purchase Streptococcus pneumoniae, Streptococcus alpha-hemolytic, Streptococcus beta-hemolytic, Staphylococcus aureus, Staphylococcus epidermidis, Neisseria catarrhalis, Haemophilus influenzae, A aeruginosa from National Culture Collection Bacteria, Proteus, Escherichia coli, Klebsiella pneumoniae, Candida albicans standard strains each 2.

[0022] One of them was dissolved in 0.5ml sterilized physiological saline, inoculated in the corresponding culture medium, and cultured by streaking in regular divisions, and cultured at 37°C for 24-48 hours. Among them: Staphylococcus aureus, Staphylococcus epidermidis, A. aeruginosa, Proteus, Neisseria catarrhalis, and Klebsiella pneumoniae were inoculated in ordinary medium; A-hemolytic streptococcus, B-hemolytic Streptococcus was inoculated in fresh blood medium; Escherichia coli was inoculated in SS medium; Candida albicans was inoculated in Sabouraud medium; Bacillus influenzae was inoculated in chocolate medium; Streptococcus...

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PUM

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Abstract

The present invention relates to a combined bacterial vaccine for curing allergic diseases of allergic rhinitis, allergic conjunctivitis, various bronchitis and asthma and deafness resulted from medicine with good therapeutic effect. Said combined bacterial vaccine is formed from diplococcus pneumoniae, alpha-hemolytic streptococcus, beta-hemolytic streptococcus, staphylococuus aureus, staphylococcus epidermidis and others.

Description

technical field [0001] The invention relates to a pharmaceutical preparation containing bacteria, in particular to a combined bacterial vaccine for treating allergic diseases and a preparation method thereof. technical background [0002] Allergic diseases are more common in dermatology, respiratory medicine, and ENT. The clinical manifestations are various diseases such as atopic dermatitis, eczema, allergic rhinitis and asthma, accounting for about 20-50% of outpatient visits in various departments. Modern immunomedicine believes that the main mechanism of allergic diseases is: genetic factors as the background, foreign antigen-induced, Th2 cell-mediated I-VI allergy. There are many clinical treatment methods, mainly antihistamine drug treatment. As for the desensitization treatment for foreign antigens, due to the difficulty in finding allergens and the limitation of specific antigen preparation, clinical use is rare. [0003] It has been reported in foreign literature ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/02A61P11/00A61P11/06A61P27/16A61P37/08
Inventor 张玉环张理涛赵振宇杨新建孙晓惠赵宏丽
Owner 天津市长征医院
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