Liver disease treating preparation

A preparation and dosage form technology, applied in the field of Yugan preparations, can solve problems such as side effects, expensive medicines for patients, and expensive medicines

Inactive Publication Date: 2005-02-02
斯拉甫·艾白 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the drugs used for the treatment of viral hepatitis and liver disease at home and abroad are roughly divided into three categories: (1) antiviral drugs, mainly interferon and several nucleoside analogs, these drugs can be used for about 6 months after stopping the drug. Most patients will relapse within 1 year and the drug costs are expensive; (2) Immunomodulatory drugs, such as transfer factor, interleukin-2, thymosin, etc., the efficacy of such drugs in the treatment of chronic hepatitis is yet to be confirmed, and the drug costs are expensive and have side effects

Method used

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  • Liver disease treating preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] a. Take Artemisia argyi 10% and pulverize it, use medical ethanol to reflux extract 3 times, wherein the amount of ethanol accounts for 4400% of the total amount of Artemisia annua, recover ethanol under reduced pressure, and filtrate to an extract with a relative density of 0.9, add petroleum ether, and heat at 30°C, degrease until colorless, extract the residue with ethyl acetate, recover the ethyl acetate under reduced pressure to obtain an oily substance, concentrate under reduced pressure, and dry in vacuum for later use, wherein the content of ketoacids and flavonoids in the active part of Artemisia argyi is 50%.

[0070] b. Pulverize 90% of Hypericum perforatum, extract 3 times with medical ethanol reflux, wherein the amount of ethanol is 4400% of the total amount of Hypericum perforatum, to obtain Hypericum perforatum extract, dry for later use, wherein the effective part of Hypericum perforatum is benzo The content of dianthrones and flavonoids is 80%; benzodant...

Embodiment 2

[0074] a. Pulverize 85% of Artemisia annua, extract 3 times with medical ethanol reflux, wherein the amount of ethanol is 4400% of the total amount of Artemisia annua, recover ethanol under reduced pressure, and filtrate to an extract whose relative density is 1.30, add petroleum ether, and increase temperature at 45°C, degrease until colorless, extract the residue with ethyl acetate, recover the ethyl acetate under reduced pressure to obtain an oily substance, concentrate under reduced pressure, and dry in vacuum for later use. The total ketoacids and flavonoids content in the effective parts of Artemisia argyi is 80%;

[0075] b. Grind 15% of Hypericum perforatum, and reflux extraction with medical ethanol for 3 times, wherein the amount of ethanol accounts for 4400% of the total amount of Hypericum perforatum, to obtain Hypericum perforatum extract and dry it for later use, wherein the effective part of Hypericum perforatum is benzodi Anthrone content is 50%; benzodanthrones...

Embodiment 3

[0079] a. Pulverize 75% of Artemisia annua, extract 3 times with medical ethanol reflux, wherein the amount of ethanol accounts for 4400% of the total amount of Artemisia annua, recover ethanol under reduced pressure, and filtrate to an extract whose relative density is 1.0, add petroleum ether, temperature at 40°C, degrease until colorless, extract the residue with ethyl acetate, recover the ethyl acetate under reduced pressure to obtain an oil, concentrate under reduced pressure, and dry in vacuum for later use. The total ketoacids and flavonoids content in the active parts of Artemisia argyi is 70%;

[0080] b. Grind 25% of Hypericum perforatum, extract 3 times with medical ethanol under reflux, wherein the amount of ethanol is 4400% of the total amount of Hypericum perforatum, to obtain Hypericum perforatum extract, dry for later use, wherein the effective part of Hypericum perforatum is benzo The content of dianthrones and flavonoids is 55%; benzodanthrones: including hype...

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Abstract

The present invention relates to a liver disease treating preparation which is an oral medicine prepared for curing virus hepatitis and hepatopathy based on the long year clinical experience of herbalist doctor and nation medicine specialists. The preparation contains a branch of wormwood and a hypericum, the wormwood and hypericum are comminuted, extracted, filtered, and are used for preparing extract by sponging drying method, one branch of wormwood is decolored, eluted, concentrated and the mixed with the hypericum extract to make oral solid preparation and liquid preparation by conventional method; the medicine is tested by body and outer body antivirus experiment, the result indicates that: it has important application foreground for curing virus hepatitis and hepatopathy and AIDS; the liver disease treating preparation has obvious effect in clinical use fro curing virus hepatitis and hepatopathy.

Description

technical field [0001] The invention relates to a liver-reinforcing preparation, which is an oral medicine for treating viral hepatitis and liver disease. Background technique [0002] At present, the incidence of viral diseases at home and abroad is increasing year by year, and new immunodeficiency diseases such as AIDS appear. The drug varieties used to treat this type of disease are roughly divided into two categories: 1. antiviral drugs, and 2. immunomodulatory drugs, but they all have their own problems and cannot achieve the purpose of curing. Therefore develop the therapeutic drug with good antiviral effect and little side effects, which is an urgent need in the medical circle. [0003] Viral hepatitis is a worldwide common disease, and my country is an epidemic "hardest hit area". It is predicted that there are more than 100 million people infected with hepatitis B in my country, and about 30 million patients with abnormal liver function caus...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P1/16A61P31/12
Inventor 斯拉甫·艾白哈木拉提·吾甫尔
Owner 斯拉甫·艾白
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