Novel ceramide compound with cell fading inducing activity and its preparing method
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- SHENYANG PHARMA UNIVERSITY
- Publication Date
- 2005-05-18
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
Technical field:
[0001] The invention relates to the extraction and separation of biologically active compounds from the fermentation liquid of marine fungi, in particular to the novel ceramide compound Altermides which has the activity of inducing cell apoptosis and is extracted and separated from the fermentation liquid of marine fungus Alternalia sp. Background technique:
[0002] Marine microorganisms have proven to be a rich source of novel antibiotic, antineoplastic and antiinflammatory drugs (Fenical, W. Chem. Rev., 93, 1673-1683 (1993).). In recent years, a lot of active compounds with novel structures have been isolated from the metabolites of marine microorganisms. The research on marine microorganisms mainly includes marine bacteria, fungi, actinomycetes and marine cyanobacteria. With the deepening of research on marine bacteria In recent years, there have been more and more studies on marine fungi. It has been proved that marine fungi can produce more new active ...