Composition of transiron protein and biological reducing agent and its preparation method

Abstract

A compound of the active anticancer protein and bioreducer for preparing the medicine to treat cancer is prepared from the target protein chosen from transferrin, ceruloplasmin, somatostatin, vitamine bindin, etc and the bioreducer chosen from bifunctional heterocyclic nitro compound, quinone, heterocyclic NOx, topoisomerase B inhibitor and DNA-targeting medicine.

Description

1. Technical field [0001] The invention belongs to the technical field of biopharmaceuticals, and in particular relates to a combination of a protein and a biological reducing agent effective in treating cancer, especially a combination of a targeting protein and a biological reducing agent. 2. Background technology [0002] At present, the two biggest problems encountered in the treatment of tumors are drug resistance and drug toxicity. One way to solve drug resistance and drug toxicity is to target drugs to tumor cells. Many researchers have devoted themselves to the study of using antibodies and other means to achieve the goal of targeting. Although these have achieved some results, they have also attracted a lot of attention. series of new questions. For example, antibodies usually bind to normal tissues and can even cause severe allergic reactions, while microsomes are poorly targeted. [0003] Transferrin (Transferrin) is a β1 globulin with a molecular weight of abou...

AI Technical Summary

Problems solved by technology

For example: Antibodies usually bind to normal tissues and can even cause severe allergic reactions, but microsomes are poorly targeted