Vaginal tablet with clindamycin and metronidazole

Abstract

The invention relates to a vaginal tablet of clindamycinum and metronidazole, which uses the salts or esters of clindamycinum and metronidazole as the active constituents, and the conventional tablets as the auxiliary material.

Description

Technical field: [0001] The invention relates to a vaginal tablet of clindamycin and metronidazole, which belongs to the field of chemical medicines. Background technique: [0002] Vaginitis is a common clinical disease in obstetrics and gynecology. A variety of pathogenic microorganisms can cause female reproductive tract infections. Common vaginitis is; Bacterial vaginosis, Trichomonas vaginitis, Candida albicans (fungal) vaginitis. [0003] G in normal vagina + Bacillus, G - Bacillus, G + Cocci, G - coccus; and other microorganisms such as Mycoplasma hominis, Ureaplasma, yeast, etc. Under the balance of flora, it will not cause disease. Whenever the ecological environment of the vagina changes and the immune function of the vagina is out of balance, the flora in the normal vagina is out of balance or infected with pathogenic pathogens, the vagina is prone to various vaginitis. [0004] Bacterial vaginosis (Bacterial vaginosis, BV) is the most common vaginal infecti...

AI Technical Summary

Problems solved by technology

[0012] 1. Systemic medication has a slow effect on local bacteria in the vaginal cavity, a long cycle, and large toxic and side effects on the body;

[0013] 2. For vaginal mixed infection of bacteria and trichomonas, there is no single compound preparation that is convenient to use and has a definite curative effect. Generally, 2-3 local preparations need to be applied, which is inconvenient to use and expensive;

[0014] 3. Because of the short residence time of Chinese herbal medicine, not only the effect is not obvious, but unreasonable washing may also destroy the acidic environment of the vagina, leading to bacterial imbalance and aggravating the development of the disease