Duloxetine enteric coated tiny pill capsule, and preparation method

A technology of duloxetine intestines and loxetine intestines, which is applied in the direction of bulk delivery, nervous system diseases, active ingredients of heterocyclic compounds, etc., and can solve problems that do not involve solid dispersion technology
CN1759829AActive Publication Date: 2006-04-19SHANGHAI INST OF PHARMA IND CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI INST OF PHARMA IND CO LTD
Publication Date
2006-04-19

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Abstract

An enteric micropill (microsoftgel) of Duluoxiting and its preparing process are disclosed. Said micropill is composed of an empty core pill and a coated external layer consisting of a principal medicine layer, an isolating layer and an enteric layer. It features that its principal medicine can be quickly released only in small intestine.
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Description

technical field

[0001] The invention relates to an oral preparation of duloxetine and its salts, in particular to a duloxetine enteric-coated pellet capsule and a preparation method thereof. Background technique

[0002] Depression is one of the leading causes of loss of work and life. As fatigue progresses, patients lose the ability to make decisions, function normally, or perform basic self-care activities. The acceleration of the pace of modern life and the increase of social pressure have brought great challenges to people's psychological endurance. According to the latest medical literature, about 12% of people suffer from depression, but the effective rate of antidepressants currently available clinically is less than 70%, and the onset time is generally more than 15 days, and some are difficult to tolerate Many patients lose confidence in treatment due to side effects (sexual dysfunction, severe gastrointestinal reactions).

[0003] Duloxetine, chemically named (+)...

Claims

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