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Aizoon stonecrop granule and its preparation process

A technology of sedum notoginseng and granules, which is applied in the direction of medical formulas, medical preparations containing active ingredients, block transportation, etc., can solve the problems of large volume of syrup preparations, easy to mold and deteriorate, and inconvenient to carry, and achieve light weight and Easily soluble, easy to preserve, and convenient to store

Inactive Publication Date: 2006-10-04
石圣洪
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Sedum notoginseng syrup also has the following major defects: 1. The syrup preparation occupies a relatively large volume and is heavy and inconvenient to carry; 2. The liquid preparation needs to be added with preservatives, and is prone to mildew and deterioration

Method used

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  • Aizoon stonecrop granule and its preparation process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] 1) Water extraction: Take 6000g of Sedum Sanqi, add water to decoct twice, add 12 times the weight of Sedum Sanqi for the first time, decoct for 2 hours; add 10 times the amount of water for the second time, decoct for 1 hour, Combine the decoctions, filter, and concentrate the filtrate into a clear paste with a relative density of 1.20 under the conditions of a temperature of 65°C and a vacuum of 0.08mpa, and the clear paste is set aside;

[0014] 2) Alcohol precipitation: add ethanol to the above clear cream to make the clear cream contain 60% alcohol, let it stand for 36 hours, take the supernatant, recover the ethanol and concentrate it at a temperature of 65°C and a vacuum of 0.1mpa Form into a dry paste with a relative density of 1.35, pulverize it, and make the dry paste powder for later use. The yield of sedum notoginseng in the pilot test is about 8.3%, and the amount of cream produced here is about 498g, that is, 498g of dry cream.

[0015] 3) Granulation: Ad...

Embodiment 2

[0018] 1) Water extraction: Take 5000g of Sedum Sanqi, add water to decoct twice, add water 10 times the weight of Sedum Sanqi for the first time, decoct for 1.5 hours; add 8 times the amount of water for the second time, decoct for 0.5 hours, Combine the decoctions, filter, and concentrate the filtrate into a clear paste with a relative density of 1.10 under the conditions of a temperature of 60°C and a vacuum of 0.06mpa, and the clear paste is set aside;

[0019] 2) Alcohol precipitation: add ethanol to the above clear paste to make the alcohol content of the clear paste reach 55%, let it stand for 24 hours, take the supernatant, reclaim the ethanol and concentrate it under the condition that the temperature is 60°C and the vacuum degree is 0.06mpa. Dry paste with a relative density of 1.3, pulverized, dry paste powder for later use;

[0020] 3) Granulation: Add 0.8 part of starch and 0.003 part of cyclamate or steviol to the above dry paste powder, mix well, make granules w...

Embodiment 3

[0022] 1) Water extraction: take sedum notoginseng, add water and decoct 3 times, add water 15 times the weight of sedum notoginseng for the first time, decoct for 2.5 hours; add 12 times the amount of water for the second time, decoct for 1.5 hours; Add 8 times the amount of water three times, decoct for 1 hour; combine the decoction, filter, and concentrate the filtrate into a clear paste with a relative density of 1.30 under the conditions of a temperature of 70°C and a vacuum of 0.12mpa, and clear the paste for later use;

[0023] 2) Alcohol precipitation: add ethanol to the above-mentioned clear paste to make the alcohol content of the clear paste reach 70%, let it stand for 48 hours, take the supernatant, reclaim the ethanol and concentrate it at a temperature of 65°C and a vacuum of 0.1mpa. Dry paste with a relative density of 1.4, pulverized, dry paste powder for later use;

[0024] 3) Granulation: Add 1.2 parts of dextrin and 0.005 part of sodium saccharin to the abov...

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Abstract

The invention provides a medicinal composition and its preparing process, wherein the composition is prepared from aizoon stonecrop through the steps of condensatiing into concrete, charging auxiliary material and flavoring agent to obtain granules.

Description

(1) Technical field: [0001] Sedum notoginseng granules and a preparation method thereof belong to a pharmaceutical composition, and in particular relate to a medicine prepared from plant traditional Chinese medicines and a preparation method thereof. (two) background technology: [0002] From the point of view of traditional Chinese medicine, any disease caused by burning heat or qi deficiency caused by various reasons causes the blood to not follow the normal path, or overflow to the orifices of the mouth and nose, or drain to the front and rear yin, or ooze out of the skin. , collectively referred to as blood syndrome. In other words, diseases with non-physiological bleeding as the main clinical manifestation are called blood syndromes. The common ones are epistaxis, teeth bleeding, hemoptysis, vomiting blood, blood in the stool, hematuria, purpura and so on. For various bleeding symptoms, there are many hemostatic drugs on the market. Western medicine has different drug...

Claims

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Application Information

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IPC IPC(8): A61K36/41A61K9/16A61P7/04
Inventor 黄亮杨帆
Owner 石圣洪
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