Medical usage of S-adenyhomotype cysteine
A cysteine and adenosine isomorphic technology, which is applied in the field of medical application of S-adenosylhomocysteine, can solve the problem that there is no research on the impact of S-adenosylhomocysteine on the immune system
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[0021] Experimental drugs, animals and materials
[0022] Drug name: S-adenosine homocysteine (S-(5'-Adenosyl)-L-homocysteine), MW: 384.4.
[0023] Experimental animals: Balb / c mice, C57BL / 6 mice, 6-8 weeks old, all female mice, purchased from Shanghai Experimental Animal Center of Chinese Academy of Sciences, animal qualification certificate number: Zhongke Hudongguan No. 99- Number 003. MRL-lpr / lpr mice were introduced from Japan and provided by the SPF animal room breeding of Shanghai Institute of Materia Medica, Chinese Academy of Sciences. The animals were kept in a clean animal room of the Shanghai Institute of Medicine, Chinese Academy of Sciences, with a 12-hour light / dark cycle, a room temperature of 24°C, and a humidity of 50-60%.
[0024] Reagents:
[0025] Pertussis toxin (Pertussis toxin, PTX) and Ovalbumin (grade V) were purchased from Sigma (St. Louis, MO, USA).
[0026] Complete Freund's adjuvant (CFA) and Mycobacterium tuberculosis (Mycobacterium tuberculosis H3...
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