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Application of water soluble chitosan in toothpaste and mouthwash

A water-soluble chitosan, chitosan technology, applied in dentistry, oral care, medical science, etc., to prevent dental caries and ensure oral health

Inactive Publication Date: 2007-05-30
王立君
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The application of water-soluble chitosan as oral health product has not been reported as far as the inventor knows

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0015] The preparation of this water-soluble chitosan stock solution, 250g deacetylation degree 80% water-soluble chitosan is dissolved in 0.9%, in 750ml physiological saline, square filter, remove impurity, obtain deacetylation degree and be 80% water-soluble shell Polysaccharide solution, sterilization and disinfection.

[0016] Preparation of 2.5% water-soluble chitosan mouthwash, 250 grams of water-soluble chitosan with a deacetylation degree of 80%, add 0.9% physiological saline to dissolve, add deionized water to 1000ml, and stir to obtain 25% water-soluble chitosan Sugar Concentrate. Get 400ml of 25% water-soluble chitosan concentrated solution, add 1.3 grams of vitamin B and a little essence, then filter and sterilize to obtain 2.55% water-soluble chitosan-containing mouthwash.

[0017] The toothpaste containing 2.5% water-soluble chitosan is prepared. After the toothpaste is made into paste, water-soluble chitosan is added in proportion to the weight to prepare the t...

Embodiment 1

[0020] Embodiment 1: This product is packed into a vacuum tank, sprayed into the oral cavity twice every day, and after 5 people used it, the oral ulcer surface began to heal after one day.

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PUM

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Abstract

The invention discloses an application of soluble chitose as oral article, which is characterized by the following: sterilizing Gram-positive bacterium and negative bacterium due to 0.1-20% soluble chitose; possessing affinity with oral bacteria and oil anion; repairing ulcer; accelerating microcirculation of surface capillary; augumenting the response of immune cell in the deep layer.

Description

technical field [0001] The invention relates to the application of water-soluble chitosan as oral products, in particular to the application of water-soluble chitosan as toothpaste and mouthwash. Background technique [0002] Water-soluble chitosan Water-soluble chitosan refers to a class of chitosan that can be dissolved in neutral water, mainly including chitosan with a moderate degree of deacetylation, chitosan salt, and carboxymethyl chitosan. Chitin is modified after deacetylation, and it is widely distributed in nature. It exists in the shells of aquatic arthropods such as shrimps and crabs, the exoskeletons of molluscs, and fungi. Moderately deacetylated chitosan refers to chitosan whose uniform deacetylation degree is about 55% in the molecular internal structure. , so the original secondary structure of the molecular chain is destroyed, making its crystallization almost impossible to finalize, so it has the characteristics of being soluble in neutral water. Chitos...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61Q11/00
Inventor 王立君
Owner 王立君
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