High artemisinin yielding plant genotype 'CIM-Arogya'

Inactive Publication Date: 2005-10-06
COUNCIL OF SCI & IND RES
View PDF4 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0001] The present invention was related to the development of a novel, distinct high herb and artemisinin yielding genotype of Artemisia annua obtained through systematic marker assisted breeding followed by selection of uniform population in a methodical way. This invention further relate

Problems solved by technology

According to Meshnick et at., (1996) (Microbiological Reviews 6:301-315) the antimalarial endoperoxides including artemisinin, dihydroartemisinin and arteethers, are not likely to be useful for other therapeutic purposes except against malarial parasites.
Although artemisinin rapidly suppresses the activity of parasites like Plasmodium vivax and P. falciparum, problems with high rate of recrudescence (>10% recrudescence infections), short half life persist.
(causing tuberculosis), Haenzophilus sp. and Haemophilus influenzae are gradually becoming ineffective due to the occurrence of mutatious in gyrase genes and their natural selection under continuous use of such drug.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • High artemisinin yielding plant genotype 'CIM-Arogya'
  • High artemisinin yielding plant genotype 'CIM-Arogya'
  • High artemisinin yielding plant genotype 'CIM-Arogya'

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0008] Accordingly, the present invention relates to a new and distinct genotype of Artemisia annua ‘CIM-Arogya’, developed through marker assisted breeding, possessing the following combination of characters: [0009]Genus.—Artemisia. [0010]Species.—annua. [0011]Family.—Asteraecae. [0012]Common name.—Qinghao. [0013]Plant height.—280-305 cm. [0014]Plant canopy.—Oval. [0015]Growth habit.—Erect. [0016]Branching.—sympodial branching pattern. [0017]Stem.—Single, round hard woody green (137D) Stem width 5-12 cm (app). [0018] Number of branches: [0019]Primary branches.—55-65. [0020]Secondary branches per primary branch.—50-60. [0021]Tertiary branches per secondary branch.—37-45. [0022] Range of length of internodes: [0023]Main stem.—4-6 cm at bottom, 10-12 cm at middle, 2-5 cm at the top. [0024]Primary branch.—2-5 cm at bottom, 8-11 cm at middle, 2-4 cm at the top. [0025]Secondary branch.—8-11 cm at the bottom, 5-7 cm at the middle, 1-3 cm at the top. [0026]Tertiary branch.—3-5 cm at the bo...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Diameteraaaaaaaaaa
Lengthaaaaaaaaaa
Currentaaaaaaaaaa
Login to View More

Abstract

The present invention is related to the development of a novel, distinct high herb and artemisinin yielding genotype of Artemisia annua obtained through systematic marker assisted breeding followed by selection of uniform population in a methodical way wherein the genotype is distinct, uniform and stably maintainable by continuous rouging of off types in the population using DNA marker at early seedling stage from nursery itself and suitable for commercial cultivation.

Description

FIELD OF THE PRESENT INVENTION [0001] The present invention was related to the development of a novel, distinct high herb and artemisinin yielding genotype of Artemisia annua obtained through systematic marker assisted breeding followed by selection of uniform population in a methodical way. This invention further relates to marker assisted breeding to reach the high artemisinin yielding genotype. The genotype is distinct, uniform and stably maintainable by continuous rouging of off types in the population using DNA marker at early seedling stage from nursery itself and suitable for commercial cultivation. BACKGROUND AND PRIOR ART REFERENCES OF THE PRESENT INVENTION [0002] Many Artemisia species are cited by early herbalists including Theophrastus in the third century B.C (Einarson and Link., 1976), Pliny (Bostock and Riley., 1855-1857) and Dioscorides (Gunther., 1959) in the first century BC. Wormwood (probably the species A. judaica) is mentioned in the Bible (Rev 8:10,11). In 340...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A01H1/00A01H5/02C12N15/82C12N15/87
CPCA01H5/025A01H5/02A01H6/14
InventorKHANUJA, SUMAN PREETPAUL, SHILPISHASANY, AJITGUPTA, ANILDAROKAR, MAHENDRAGUPTA, MADANVERMA, RAMRAM, GOVINDKUMAR, ANURADDHALAL, RAJBANSAL, RAVISINGH, ANILBHAKUNI, RAJENDRATANDON, SUDEEP
OwnerCOUNCIL OF SCI & IND RES