System and method for genetic based efficacy testing

Abstract

System and methods for alerting a healthcare provider to prescribed treatments having reduced or no effectiveness due to genetic composition is provided. A database containing treatments known to have reduced or no efficacy in persons having particular genetic markers is queried to determine whether any treatments prescribed by, or likely to be prescribed by, a healthcare provider to the patient are known to have reduced or no efficacy in persons having the same genetic markers as the patient. An alert containing such information is displayed at a healthcare provider system.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application is a continuation of U.S. application Ser. No. 16 / 674,189 filed Nov. 5, 2019, which is a continuation-in-part of U.S. application Ser. No. 16 / 441,597 filed Jun. 14, 2019, which claims the benefit of U.S. Provisional Application Ser. No. 62 / 685,479 filed Jun. 15, 2018 and U.S. Provisional Application Ser. No. 62 / 773,424 filed Nov. 30, 2018, the disclosures of all of which are hereby incorporated by reference as if fully restated herein.TECHNICAL FIELD[0002]Exemplary embodiments relate generally to a system and method for genetic based efficacy testing.BACKGROUND AND SUMMARY OF THE INVENTION[0003]A person visiting a doctor may present with one or more symptoms. Based on the symptoms presented, test results, or underlying conditions or diseases diagnosed, the person may be prescribed one or more medications or other treatment options by the healthcare provider as part of a treatment program. These prescribed treatments may be...

AI Technical Summary

Benefits of technology

The disclosed systems and methods streamline the process of ordering and eligibility for genetic testing, making it easier for healthcare providers to determine which tests are covered by insurance. The system can also suggest suitable treatment options based on the testing results. Additionally, the system can be integrated into existing healthcare systems without requiring a complete redesign, making it easier to provide relevant information to healthcare providers. Overall, the system improves the efficiency and effectiveness of genetic testing, making it a more useful tool in healthcare.

Problems solved by technology

Over prescription or dosing of treatments, particularly of medications, may cause side effects or other undesirable consequences.

Under prescription or dosing of treatments, particularly of medications, may bring about ineffective results, side effects, or other undesirable consequences.

For example, a person's genetic makeup may cause some medications or dosages to be wholly or partially ineffective.

Prescription of treatments to a person who has a genetic makeup that makes the treatment wholly ineffective may waste resources and unnecessarily expose the person to the risk of side effects.

Similarly, prescription of treatments to a person who has a genetic makeup that makes the treatment partially ineffective may result in less that desirable therapeutic effects, require a larger dosage, or the like to be effective.

However, the patient's individual genetic makeup or physiology may alter the effectiveness of the prescribed blood thinner.

For example, without limitation, the blood thinner may have a reduced effectiveness in persons carrying specific genetic markers.

As a further example, again without limitation, the prescribed blood thinner may be wholly ineffective in persons carrying specific genetic markers.

Current systems, such as electronic medical record systems (EMR), are often unable to accept genomic information in a meaningful way and / or lack a dedicated space for such genetic information.

A healthcare provider may not even be aware that certain genomic testing is available that can determine the efficacy of various treatment options, such as medications.

The results may be analyzed and ineffective treatment options, such as but not limited to medications, may be identified.

Alternatively, or additionally, ineffective treatments and / or dosages may be identified.

However, if the person has a genetic makeup which would make such medication ineffective, a surgical option may instead be suggested.

Images