9 results about "Azacyclopropane" patented technology

The present application relates to the technical field of BOPP film, in particular to a scratch-resistant glue-free matt film and a preparation method thereof, the scratch-resistant glue-free matt film comprises a matt layer, a core layer and a thermal composite layer arranged in sequence, the matt layer comprises copolymerized polypropylene, high-density polyethylene, 2.0-2.5 wt% maleic anhydride modified aziridine as an end group of linear alkyl silicone (weight average molecular weight 120-150 thousand, surface tension 42-45 mN / m) and 2000-4000 ppm spherical polymethyl methacrylate (particle size D50 is 4.0-5.0 microns); the core layer comprises homopolymerized polypropylene; and the thermal composite layer comprises ethylene-vinyl acetate copolymer and 2000-4000 ppm spherical anti-blocking agent. Through the synergistic design of the components of the matt layer and the thermal composite layer, the scratch-resistant glue-free matt film realizes the balance of the surface scratch resistance of the matt layer, the high surface tension (printability) and the smoothness of the winding and unwinding, and provides a solution to the common problem of the scratch resistance of the matt surface for high-end BOPP matt film.

The invention discloses a gram-level synthesis method of Dactyllactone A. The gram-level synthesis method of Dactyllactone A is shown in the description. The method comprises the following steps: with simple and easily available aryl iodide, aziridine and triisopropyl silylacetylene as starting materials, stirring and reacting in an organic solvent at 60-70 DEG C under the action of a palladium catalyst, a phosphine ligand, a norbornene derivative and alkali to obtain a key intermediate; the key intermediate is condensed with iodo gem-dimethyl ester furanone prepared from propiolic acid and dimethyl malonate iodine ylide, and then the condensation product is subjected to an Au / Ag catalyzed intramolecular hydroamination reaction, photocatalytic 6-pi electro-cyclization and two-step conversion, so that the natural product Dactyllactone A can be obtained, wherein the iodo gem-dimethyl ester furanone and iodo gem-dimethyl ester furanone are prepared from propiolic acid and dimethyl malonate iodine ylide. The method has the advantages of cheap and easily available raw materials, short reaction steps, high reaction efficiency, large preparation scale, simple preparation process and the like, has great application potential, and lays a good foundation for industrial production.

The invention relates to a preparation method of chiral beta-substituted phenylethylamine and a derivative thereof, which comprises the following step: by taking aziridine as a raw material, nickel salt as a catalyst and a chiral ligand as a ligand and a metal reducing agent, carrying out asymmetric cross electrophilic coupling reaction to prepare the chiral beta-substituted phenylethylamine. The chiral beta-substituted phenylethylamine and the derivative thereof are obtained in one step by adopting a nickel-catalyzed asymmetric electrophilic cross-coupling method, and the method has the advantages of high step economy, high reaction efficiency, less pollutant emission and the like.

This invention relates to the field of coating technology, specifically to a printing coating for colored paper and its preparation method. In the preparation process, this invention incorporates dithiol dihydroxyacetic acid to increase the crosslinking points of the system, and trimethylolpropane tris(2-methyl-1-azacyclopropane propionate) containing an unstable aziridine three-membered ring to improve the degree of crosslinking. It also introduces isoborneol methacrylate to reduce internal stress, effectively balancing the crosslinking density and volume shrinkage of the system, resulting in a coating with excellent adhesion. Furthermore, this invention adds the bifunctional monomer 1,6-hexanediol diacrylate to make the network structure more uniform and provide anti-photooxidation properties, making the system less prone to oxidative discoloration. The addition of tripropylene glycol diacrylate reduces the risk of yellowing caused by small molecule migration. Therefore, the coating obtained in this way has significant anti-yellowing effects, preventing color distortion of colored paper and maintaining the appearance stability of the colored paper.

The invention provides a bidentate organic tellurium salt catalyst as well as a preparation method and application thereof. The bidentate organic tellurium salt catalyst has a structure as shown in a formula (I). According to the bidentate organic tellurium salt prepared by the invention, the activity of a chalcogenide bond catalyst is improved by introducing an electron-deficient aryl substituent and optimizing a linking group. A series of bidentate organic tellurium catalysts are efficiently developed and have excellent performance in activation of an azetidine structure and an aziridine structure, and it is proved that the chalcogenide bond action capacity of the bidentate organic tellurium catalysts is enhanced. This activation in turn initiates a [4 + 2] cycloaddition reaction with an unactivated olefin or alkyne.

The invention discloses a method for enantioselective synthesis of NH-aziridine, which comprises the following steps: in the presence of a chiral phosphoric acid catalyst, reacting alpha-cyano heterocyclic conjugated olefin as shown in a formula (I) with N-acyloxyhydroxylamine in an organic solvent to obtain NH-aziridine as shown in a formula (II), according to the present invention, the method can be smoothly performed in the inert organic solvent at the temperature of-40-25 DEG C, the substrate can suitably cover pyridine, quinoline, benzimidazole, benzothiazole, benzoxazole and other N-heteroaromatic rings, the product yield is high, and the enantiomeric excess (ee) can be up to 99%. Inorganic additives (such as magnesium oxide) may be optionally added during the reaction to increase yield on individual substrates without affecting enantioselectivity. The method avoids the traditional multi-step sequence of nitrogen protection first and then deprotection, and has the advantages of economical steps, mild conditions, feasible amplification and the like.

The present invention relates to the field of medicine and provides a chloroethylnitrosourea compound containing an aromatic group. The chloroethylnitrosourea compound containing an aromatic group has the following general structural formula: #imgabs0# wherein R is selected from -CH3, -CH2CH3, or #imgabs1#, and Ar is selected from benzene, substituted benzene, #imgabs2#, or #imgabs3#. The chloroethylnitrosourea compound containing an aromatic group of the present invention has a higher ability to penetrate the brain barrier, fully utilizes the effect of the aziridine ion, and has excellent anti-glioma cell activity, and also exhibits anti-tumor cell activity against various tumors.

The application discloses a kind of synthesis 13 The application discloses a method for synthesizing C-labeled 4-trifluoromethyl aryl formate and application thereof.The method has mild reaction conditions and simple preparation process.Further, the method uses aryl iodide, epoxide or aziridine as raw materials, and reacts with 13 C-labeled 4-trifluoromethyl aryl formate is used as a starting material, and under the action of a palladium catalyst, a phosphine ligand, a norbornene derivative, a base and an additive, a series of C-labeled isochromane ketone compounds and dihydroisoquinoline ketone compounds can be synthesized by stirring at 60 DEG C in an organic solvent. 13 C-labeled isochromane ketone compounds and dihydroisoquinoline ketone compounds have important theoretical value and application potential.

This invention belongs to the field of organic chemical synthesis technology, specifically relating to an ethyl-base derivative, its preparation method, and its applications. The ethyl-base derivative provided by this invention is a compound with the structure shown in Formula I. The above-mentioned compound provided by this invention is an enantiomeric pure ethyl-base compound, possessing a nitrogen chiral center and a unique rigid structure, which can provide a structural basis for molecular recognition, supramolecular chemistry, asymmetric catalysis, and the discovery of novel drug molecules. In particular, the compound of this invention can serve as a chiral catalyst for the azahexacyclopropanation reaction of chalcones, with mild reaction conditions, moderate yield, and moderate enantioselectivity, making it suitable for application as a chiral catalyst.