This utility model relates to the field of lock box technology, and specifically discloses an anti-theft lock box and cabinet, including a shell; a base plate, the base plate being rotatably connected to the shell to form a receiving cavity for accommodating a door lock; the base plate and the shell rotating relative to each other to open or close the receiving cavity, and the shell having an opening communicating with the receiving cavity; a first anti-theft lock, disposed on the shell, used to open or close the opening from inside the shell; a second anti-theft lock, the shell and the base plate being connected or disconnected via the second anti-theft lock, the second anti-theft lock and the opening being arranged opposite to each other along a first direction, one end of an external key being able to extend through the opening into the receiving cavity to open or close the second anti-theft lock; when the second anti-theft lock is closed, the shell and the base plate are in a connected state, and the shell and the base plate are relatively fixed; when the second anti-theft lock is open, the shell and the base plate are in a disconnected state, and the shell and the base plate can rotate relative to each other. Through the above method, this utility model embodiment can improve the anti-theft security of door locks.