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Oral medicine for cardio-cerebral blood vessel diseases and its making method

A technology for cardiovascular and cerebrovascular diseases and drugs, applied in the field of medicine, can solve the problems of inconvenient medication, limited injections, and no report on the development of oral preparations of Danhong, and achieves the effects of being convenient to take, improving stability, and being easy to carry, transport and store.

Active Publication Date: 2008-05-07
SHANDONG BUCHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since cardiovascular and cerebrovascular diseases are chronic diseases and require long-term medication, the use of injections is inconvenient, especially for patients with cardiovascular and cerebrovascular diseases.
There is no report on the development of oral preparations of Danhong

Method used

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  • Oral medicine for cardio-cerebral blood vessel diseases and its making method

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Experimental program
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Effect test

Embodiment 1

[0038] The preparation of embodiment 1 tablet

[0039] (1) Take 1200g of Danshen medicinal material, clean it, crush it into coarse particles, extract it by percolation with 30% ethanol of 30 times the weight of the medicinal material, collect the percolation liquid, reclaim ethanol under reduced pressure, let stand, filter, and concentrate the filtrate under reduced pressure to The relative density is 1.18 (55°C), add ethanol to make the alcohol content reach 60%, let it stand, filter, recover the ethanol under reduced pressure and concentrate to a relative density of 1.14 (55°C), spray dry to obtain the salvia miltiorrhiza extract;

[0040] (2) Take 400g of safflower medicinal material, clean it, and soak it in water under stirring (120r / min) for 3 times, and soak it in water with 10 times the weight of the medicinal material for 2 hours each time, filter, combine the filtrate, and concentrate under reduced pressure to The relative density is 1.15 (60°C), add ethanol to make...

Embodiment 2

[0042] The preparation of embodiment 2 capsules

[0043](1) Take 2600g of Danshen medicinal material, clean it, crush it into coarse particles, extract by percolation with 35% ethanol with 25 times the weight of the medicinal material, collect the percolation liquid, recover ethanol under reduced pressure, centrifugal filter, and concentrate the filtrate under reduced pressure to relative density 1.12 (55°C), add ethanol to make the alcohol content reach 65%, let it stand, filter, recover the ethanol under reduced pressure and concentrate to a relative density of 1.13 (55°C), spray dry to obtain the salvia miltiorrhiza extract;

[0044] (2) Take 1200g of safflower medicinal material, clean it, immerse it in water under stirring (100r / min) and extract 4 times, each time use 6 times the weight of the medicinal material in water, soak it for 10 hours, filter, combine the filtrate, and concentrate under reduced pressure to The relative density is 1.16 (60°C), add ethanol to make t...

Embodiment 3

[0046] The preparation of embodiment 3 tablet

[0047] (1) Take 1600g of Danshen medicinal material, clean it, crush it into coarse particles, extract it by percolation with 25% ethanol which is 35 times the weight of the medicinal material, collect the percolation liquid, recover ethanol under reduced pressure, let it stand and filter, and the filtrate is kept at about 50°C Concentrate under reduced pressure to a relative density of 1.15 (60°C), add ethanol to make the alcohol content reach 65%, let stand, filter, recover ethanol under reduced pressure and concentrate, dry under reduced pressure, crush into fine powder, and obtain Danshen extract;

[0048] (2) Take 900g of safflower medicinal material, clean it, immerse and extract 3 times with 21 times the weight of the medicinal material in water, 7 hours each time, filter, combine the filtrate, concentrate under reduced pressure to a relative density of 1.08 (65°C), add ethanol to make The alcohol content reaches 75%, stan...

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Abstract

An orally taken Chinese medicine for treating cardiovascular and cerebrovascular diseases (coronary heart disease and apoplexy for example) is prepared from red sage root and safflower through extracting their active components and dispensing the medicine.

Description

technical field [0001] The invention relates to a Chinese patent medicine, in particular to an oral medicine for treating cardiovascular and cerebrovascular diseases with two Chinese herbal medicines of salvia miltiorrhiza and safflower as raw materials and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] Cardiovascular and cerebrovascular diseases are common and frequently-occurring diseases with high morbidity, disability, and mortality. Therefore, they are diseases that seriously endanger human health and life, and have a certain impact on family and social life. Many scholars at home and abroad are exploring the treatment and prevention of cardiovascular and cerebrovascular diseases. Traditional Chinese medicine has played an active role in the treatment and prevention of cardiovascular and cerebrovascular diseases due to its definite curative effect and low toxic and side effects. "Danhong Injection" and "Danhong...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/53A61K36/286A61K9/00A61P9/00A61P9/10
Inventor 赵涛陈志成
Owner SHANDONG BUCHANG PHARMA
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