Vaginal foam preparation of chlorhexidine acetate and its preparing process

A technology of chlorhexidine acetate and foam agent, which is applied in the directions of medical preparations containing active ingredients, pharmaceutical formulas, organic active ingredients, etc., can solve the problems of inability to reach the inside of the vagina, short retention time of lotion, and many auxiliary tools, etc. , to achieve the effect of good effect, less systemic side effects and less dosage

Active Publication Date: 2008-10-22
贵州宏宇药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The lotion stays in the vulva for a short time, cannot reach the inside of the vagina, cannot clean the deep part of the vagina for a long time, and requires more auxiliary tools, which is troublesome to use
At the same time, manual operation is easy to cause cross-contamination

Method used

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  • Vaginal foam preparation of chlorhexidine acetate and its preparing process

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Comparison scheme
Effect test

Embodiment Construction

[0045] Embodiments of the present invention: 15 parts of chlorhexidine acetate, 50 parts of Aina sesame oil, 45 parts of triethanolamine, 105 parts of stearic acid, 045 parts of Pingpingjia, 1000 parts of 1,2 propylene glycol, 250 parts of benzyl alcohol, and 50 parts of essence , 200 parts of ethanol, 8240 parts of distilled water. Prepare according to the following steps;

[0046] (1) Dissolving chlorhexidine acetate in ethanol and mixing it evenly with the natural plant extract to obtain No. 1 liquid;

[0047] (2) Fully dissolve triethanolamine, Pingpingjiao and stearic acid plus two-thirds of purified water in a water bath at 75°C, and mix uniformly to obtain No. 2 liquid;

[0048] (3) Add 1,2 propylene glycol or glycerol (glycerol) into No. 2 liquid, mix well to obtain No. 3 liquid;

[0049] (4) Mix the aforementioned No. 1 and No. 3 liquids in a 60°C water bath, stir evenly, add essence, benzyl alcohol and the remaining amount of purified water, mix well, pack separate...

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Abstract

The present invention discloses vaginal foam preparation of chlorhexidine acetate and its preparation process. The vaginal foam preparation is prepared with chlorhexidine acetate, blumea oil, triethanolamine, stearic acid, peregal O, glycerin, benzyl alcohol, essence, alcohol and water in certain weight proportion. It has excellent cleaning and bacteriostasis effect, and has the advantages of high safety, high stability, less side effect, low dosage, etc. and is suitable for conventional cleaning of vagina.

Description

technical field [0001] The invention relates to a women's health care product and a preparation method thereof, in particular to a foam agent for vaginal cleaning and a preparation method thereof. Background technique [0002] The vaginal gynecological cleanser commonly used both at home and abroad is mainly lotion formulation. The dosage form is a clear or suspension liquid, which needs to be poured into a container to dilute before cleaning the vulva. The lotion stays in the vulva for a short time, cannot reach the inside of the vagina, cannot have a long-term cleaning effect on the deep part of the vagina, and requires many auxiliary tools, which is troublesome to use. At the same time, manual operation is easy to cause cross-contamination Contents of the invention [0003] The object of the present invention is to provide a vaginal foam prepared with chlorhexidine acetate and a preparation method thereof, so as to solve the problems in the prior art. [0004] Techni...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/155A61K36/00A61K9/00A61P15/02
Inventor 柴立李霞余德勤杨林
Owner 贵州宏宇药业有限公司
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