Photoacoustic imaging and chromatographic imaging method based on acoustic lens and apparatus thereof

A photoacoustic imaging and tomographic imaging technology, which is applied in echo tomography, ultrasonic/acoustic/infrasonic diagnosis, acoustic wave diagnosis, etc., can solve the problems of inability to monitor tissue changes in real time, time-consuming, etc., and achieve super-resolution Effects of tomography, strong penetrating power, and damage-free sensitivity

Inactive Publication Date: 2008-12-31
SOUTH CHINA NORMAL UNIVERSITY
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Problems solved by technology

In terms of imaging methods, reconstruction algorithms are generally used to reconstruct the original photoacoustic pattern, but because the algorithm itself requires scanning or data averaging, it takes a long time, which cannot monitor tissue changes in real time

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  • Photoacoustic imaging and chromatographic imaging method based on acoustic lens and apparatus thereof
  • Photoacoustic imaging and chromatographic imaging method based on acoustic lens and apparatus thereof
  • Photoacoustic imaging and chromatographic imaging method based on acoustic lens and apparatus thereof

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Embodiment Construction

[0041] The present invention will be described in further detail below in conjunction with the examples and drawings, but the implementation of the present invention is not limited thereto.

[0042] by figure 1 It can be seen that the device of the present invention mainly includes a transparent flexible rubber layer 3, an optical fiber 4, an acoustic lens 8, a two-dimensional area array photoacoustic detector 9, a detector output signal circuit 10, a delay-signal conversion circuit 11, a capture card 12, a computer 13. The transparent flexible rubber layer 3, the optical fiber 4, the acoustic lens 8 and the two-dimensional area array photoacoustic detector 9 are installed oppositely in a cylindrical aluminum cavity 1; the optical fiber 4 is connected to the laser 7 through a connector 6 to form a light source; The optical fiber holder made of agar is fixed in the aluminum cylindrical outer cavity. The two-dimensional area array photoacoustic detector 9, the detector output signal...

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Abstract

An optoacoustic imaging and tomographic imaging method based on acoustic lens includes such steps as using pulse laser beam to irradiate biologic tissue to generate MHz-class ultrasonic (optoacoustic signal), using acoustic lens to image the laser beam excited acoustic pressure of biologic tissue and the acoustic pressures of different layers on the imaging planes, detecting the acoustic pressure distribution on some imaging plane by 2D plane array of optoacoustic sensors to obtain optoacoustic signals, and reconfiguring the tissue image of some layer. Its apparatus is composed of transparent and flexible rubber layer, optical fiber, acoustic lens, 2D plane array of optoacoustic sensors, output circuit, delay-signal conversion circuit, acquisition card and computer.

Description

Technical field [0001] The present invention relates to photoacoustic tomography imaging technology, in particular to a photoacoustic imaging and tomographic imaging method based on an acoustic lens. The invention also relates to the device used in the method. Background technique [0002] Photoacoustic tomography is an effective potential medical imaging technique to detect the light absorption distribution buried in the scattering medium. It combines the advantages of strong optical contrast and high penetration of ultrasound imaging, and has become a hot research topic. In photoacoustic imaging research, short-pulse laser (nanosecond level) is used to irradiate biological tissues. Biological tissues undergo thermoelastic expansion due to the slight increase in temperature due to the absorption of light energy, and produce ultrasound. The ultrasound signal is proportional to the light absorption of biological tissues. . Therefore, the photoacoustic signal carries information on...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B8/00A61B8/13
Inventor 唐志列陈湛旭何永恒张汉超
Owner SOUTH CHINA NORMAL UNIVERSITY
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