285 results about "Optoacoustic imaging" patented technology

The invention relates to the technical field of electronic manufacturing quality detection, and discloses a multilayer circuit board quality detection method and system, and the method comprises the steps: collecting the surface interference fringe data of a circuit board through a computer-generated holography technology, and reconstructing the three-dimensional position of an alignment mark; internal stress distribution is detected through a photoacoustic coupling system, and a three-dimensional stress tensor field is reconstructed; establishing a PCB deformation dynamic model by using a multi-layer time sequence deep learning network; establishing a stress deformation correlation model through a physical information graph neural network; realizing feed-forward compensation and process optimization according to a dynamic prediction result; according to the method, computer-generated holography, photoacoustic imaging and deep learning technologies are integrated, the registration precision and internal stress distribution of the multilayer circuit board can be detected in a lossless and high-precision mode, the dynamic change trend of the multilayer circuit board can be predicted, active compensation and process optimization are achieved, and the product quality and the manufacturing yield are effectively improved.

The invention discloses a photoacoustic spectrum-confocal Raman spectrum multi-view-field high-dimensional imaging method and a photoacoustic spectrum-confocal Raman spectrum multi-view-field high-dimensional imaging device. Nanosecond pulse laser with adjustable wavelength is generated through a continuous spectrum nanosecond pulser and a narrow-band spectrum tuning module and cooperates with a microscopic detection module, a depth imaging module, a galvanometer system and an electric displacement table to obtain spatial three-dimensional data, a photoacoustic spectrum and a Raman spectrum under multiple view fields; shallow photoacoustic spectrum-Raman spectrum tomography and deep three-dimensional photoacoustic imaging are realized; correcting a photoacoustic spectrum quantitative error by using a spectrum decoupling algorithm, and fusing the multi-view-field data to generate multi-view-field high-dimensional photoacoustic spectrum-Raman spectrum data; high-dimensional data features are extracted based on a 3D convolution instance segmentation network, and quantitative analysis and spatial distribution visualization of blood oxygen, inflammatory factors and the like are achieved. According to the method, the limitation that substances are difficult to analyze in photoacoustic imaging is overcome, the contradiction between the imaging resolution and the penetration depth is solved, and an accurate analysis means is provided for diagnosis of diseases such as knee osteoarthritis and sepsis.

The invention discloses a multi-frame photoacoustic image reconstruction method based on optical flow alignment and depth feature fusion. The method comprises the following steps: S1, obtaining photoacoustic signal data; s2, reconstructing a photoacoustic cross-sectional image; s3, performing optical flow calculation and image alignment; and S4, training the deep feature fusion network. According to the method, through optical flow motion correction and a potential space learning mechanism, space-time information and complementary features in the aligned multiple frames of images are dynamically integrated, complementary information in the multiple frames of images is adaptively fused, noise is suppressed, and finally reconstruction of high signal-to-noise ratio and high spatial resolution images of biological tissues is achieved. Experimental results show that the method can significantly improve image quality, recover image distortion and detail loss caused by motion and noise, and provide a new effective scheme for promoting robust clinical application of a photoacoustic imaging technology.

Methods, devices, apparatus, and systems for three-dimensional (3D) contoured scanning photoacoustic imaging and / or deep learning virtual staining.

The invention discloses a puncture needle track prediction method, system and device and a medium. The method comprises the following steps: acquiring continuous photoacoustic imaging image data when a puncture needle punctures in tissue; processing the photoacoustic imaging image data, extracting a needle point position, and converting each frame of image data into a feature vector about the needle point position; a Transformer model is established, the input quantity of the model is the feature vector of past image data about the position of the needle tip and priori knowledge, and the output quantity of the model is the center coordinate of the needle tip of future image data and the insertion angle of the needle tip in the surrounding tissue. Through data enhancement and constraint injection, a pure data driven model can fuse physical laws and clinical experience, finally real-time and accurate prediction of the motion trail of the puncture needle is achieved, medical employees can be helped to more accurately control the path of the puncture needle in a complex operation environment, the misoperation risk is reduced, and the operation efficiency is improved. And the safety and the accuracy of medical puncture operation are obviously improved.

The invention discloses a focused ultrasound transcranial nerve regulation and control platform and method based on photoacoustic imaging. The system comprises a synchronous pulse generator, a pulse ultrasound transmitting system, a photoacoustic signal collecting system and a fixing device. According to the method, the limitation of other imaging monitoring modes is overcome, monitoring is carried out by utilizing the characteristics of non-invasiveness, high resolution and high contrast of photoacoustic imaging, the TUS progress can be monitored for providing real-time dynamic imaging, and functional information can be provided; photoacoustic imaging is applied to focused ultrasound transcranial nerve regulation for the first time. And meanwhile, by utilizing high sound resolution and high optical contrast of photoacoustic imaging, the strongest photoacoustic signal can be provided in a near-infrared region for hemoglobin of a seat endogenous contrast agent, so that the PAT becomes an ideal imaging tool for detecting cerebral hemodynamics. In addition, key pathophysiological parameters are evaluated through functional imaging provided by the PAT, and the method can be used for evaluating brain changes in the low-intensity focused ultrasound stimulation process.

The present invention relates to an endoscopic probe for photoacoustic tomography of cavity side walls, characterized by comprising a hollow tubular probe housing with a closed front end; N acoustic wave receiving windows and M laser output windows formed on the side wall of the tubular probe housing; an array of linear laser output ports connected to a pluggable optical fiber connector via an optical fiber bundle; and an ultrasonic transducer array connected to a multi-channel signal connector via a signal harness. The present invention employs a method of arranging array transducers and array laser outputs on the side wall of the probe, eliminating the need for a reflector. The probe is less than 2 centimeters in size and can be placed in close proximity to the prostate through the rectum for photoacoustic imaging of the prostate, or in close proximity to the inner wall of the rectum for photoacoustic imaging of the inner wall of the rectum. The endoscopic probe provided by the present invention, combined with a photoacoustic imaging system host, utilizes photoacoustic endoscopic imaging technology to perform real-time transrectal prostate imaging and rectal imaging, achieving ideal imaging results.

The invention discloses a human body peripheral blood vessel photoacoustic three-dimensional imaging device and an imaging method thereof, and belongs to the field of blood vessel imaging. Through high resolution and functional monitoring capability of photoacoustic imaging, detailed blood vessel structure and blood flow dynamic information are provided, and early recognition and treatment effect evaluation of common lesions such as diabetic foot and peripheral artery diseases are promoted; meanwhile, a mechanical system is adopted, so that the detection front end with relatively high quality can be borne, and stable operation is realized, and a relatively good photoacoustic imaging result is obtained; the system has a highly stable accurate scanning imaging mode, and is convenient for multiple imaging modes of clinical application; through the arrangement of the imaging water tank and the lifting structure of the imaging water tank, switching of imaging modes in a limited space can be ensured, so that the device can be suitable for the layout of a portal type three-dimensional moving device. The system is expected to promote the portability of equipment, reduce the research and development cost of the equipment, be widely applied to clinical practice and community medical treatment, and improve the disease management level.

The invention relates to a multi-modal skin disease analysis method based on deep learning, and relates to the technical field of auxiliary diagnosis. A photoacoustic imaging device is used for scanning, a dermatoscope is used for shooting a skin disease affected part, and photoacoustic imaging data and a skin image of the affected part are obtained; aligning the photoacoustic image with a skin image, filling according to a skin image space, and combining with the skin image to obtain multi-modal skin data; constructing and pre-training a skin analysis model based on the multi-modal skin data; the pre-trained skin analysis model analyzes the collected multi-modal skin data to obtain a skin disease analysis result. The multi-modal skin data is constructed, multivariate data support is provided, and it is ensured that disease analysis is accurate and reliable. The skin analysis model extracts different scales of skin image feature maps and photoacoustic imaging feature maps so as to cover correlation between different sizes of features and different specifications of skin diseases; the other modal data is used to reinforce the own modal, and the two modal features are better combined; and the interpretability is high.

The invention relates to the technical field of photoacoustic imaging, in particular to a photoacoustic imaging system based on self-learning, which comprises an acquisition module, a screening module, an actual generation module, an ideal generation module, an adjustment module and an imaging module. According to the method, through constructing a complete closed-loop process of acquisition, screening, evaluation, self-learning optimization and image reconstruction, dynamic regulation and control of photoacoustic imaging quality are realized, and a spectrum texture gradient and an imaging uniformity error jointly define space consistency of an image; the background noise energy level and the laser energy distribution describe the stability of the signal quality; the actual definition index measures the current system performance, and the ideal definition index extracts a potential imaging upper limit under noise interference by means of a self-learning model; and the adjusting module performs adaptive optimization through the comparison result, so that the problems of low recognition accuracy and slow response speed caused by poor adaptability to different tissues due to excessive dependence on a fixed parameter model are effectively solved.

The invention relates to the technical field of photoacoustic imaging, and discloses a limited-view-angle photoacoustic image artifact suppression method, system and device and a medium. The method comprises the following steps: generating a reconstructed limited-view-angle photoacoustic image and a corresponding full-view-angle photoacoustic image through an image reconstruction algorithm; adding a sub-graph extraction module in each hierarchy except the first hierarchy of the U-Net model, and extracting a sub-graph sequence; optimizing artifact suppression model parameters based on the loss function of the structural similarity index and the average absolute value error of the limited view angle photoacoustic image and the corresponding full view angle photoacoustic image, and selecting an optimal artifact suppression model; and inputting a limited view angle photoacoustic image constructed based on an actually collected limited view angle photoacoustic signal into the trained artifact suppression model, and outputting a post-processing image after artifact suppression. The method has a good post-processing result for the photoacoustic image with the limited visual angle, artifacts can be basically and effectively inhibited, and part of loss information in the image is recovered.

The invention discloses a lithium battery tab laser welding spot detection method and system, and the method comprises the steps: building a collection system of a multispectral camera, an infrared thermal imaging camera and a photoacoustic imaging module, synchronously collecting the surface optics, internal heat distribution and microstructure characteristics of a welding spot, and reconstructing the internal defect three-dimensional distribution of a preset depth; constructing a feature association matrix, verifying association between features and defects in combination with three-dimensional distribution, and outputting fusion features containing three-dimensional distribution parameters through an attention weighted fusion network; dynamically adjusting visual parameters based on the working condition parameters; detecting defects in combination with fusion features and a causal database, and outputting a process adjustment instruction in advance by a pre-judgment module; and through 3D U-Net, micro defects are segmented and graded. The method covers the full-dimension defects, improves the false defect elimination rate, reduces the defect rate, gives consideration to the detection precision and the production efficiency, and meets the high-reliability detection requirements of the lithium battery tabs.

Systems and methods of reconstructing photoacoustic imaging data corresponding to a brain of a subject through a skull of a subject utilizing a reconstruction method that incorporates a spatial model of one or more acoustic properties of the brain and skull of the subject derived from an adjunct imaging dataset.

The invention relates to the technical field of photoacoustic imaging, in particular to a photoacoustic imaging method and system based on data analysis, and the method comprises the steps: determining the imaging state of an initial photoacoustic image according to an image abnormal coefficient and a detection domain variable value, and determining an analysis mode according to the imaging state; in the detection anomaly analysis, determining a first optimization mode according to the noise modulation coefficient; in tissue influence analysis, a second optimization mode is determined according to a distortion influence coefficient and a regional dislocation coefficient, and the second optimization mode is that an adjustment mode is determined according to a blood flow influence index, or a compensation mode is determined according to a tissue difference coefficient and deviation uniformity; the adjusting mode is that the detection angle range is adjusted according to the blood flow influence index, or the laser repetition frequency is adjusted according to the distortion influence coefficient, the compensation mode is characteristic frequency compensation or related frequency compensation, and the image quality of photoacoustic imaging can be improved.

The invention discloses a small animal in-vivo multi-parameter dynamic monitoring method based on photoacoustic imaging, and relates to the technical field of biomedical imaging, and the method comprises the steps: obtaining a photoacoustic signal generated by a small animal under the excitation of pulse laser output by an optical excitation module through an acoustic detection module; reconstructing a photoacoustic image of the photoacoustic signal through a filtering back projection algorithm; calculating the similarity between adjacent images in the photoacoustic image, identifying the image of which the similarity is lower than a set frame threshold value as a cross section slice polluted by respiratory motion artifacts and removing the cross section slice, and replacing the removed image frame by using the interpolation of an adjacent artifact-free image so as to obtain an updated photoacoustic image; selecting a region of interest in the photoacoustic image, and carrying out oxygenation kinetics monitoring, pharmacokinetics monitoring, perfusion kinetics monitoring or nanoparticle in-vivo kinetics monitoring; according to the monitoring method, motion artifacts caused by breathing of the small animals are effectively inhibited, and in-vivo multi-parameter dynamics monitoring of the small animals is achieved.

The invention discloses a head-mounted photoacoustic device for multi-parameter brain function monitoring and closed-loop regulation and control. The device comprises a nerve-lymph-blood vessel multi-mode imaging monitoring module, a multi-dimensional brain information quantitative analysis module, a closed-loop control module, a light / sound brain regulation and control module and a detachable head-mounted module. The method comprises the following steps: firstly, acquiring brain nerve, lymph and blood vessel information in real time by utilizing a multi-modal imaging monitoring module, then sending data to a multi-dimensional brain information quantitative analysis module, decoding and analyzing multi-dimensional data, extracting key features, performing multi-modal data feature fusion, and establishing an analysis method for quantitatively evaluating the brain microenvironment; therefore, the brain function state is accurately represented. The head-mounted device has the advantages that photoacoustic imaging, fluorescence imaging, optical regulation and control and ultrasonic regulation and control are added into the head-mounted device, closed-loop regulation and control parameters are achieved in a combined mode, and the functions of miniature, wearable and multi-parameter detection of the cerebral vessel-nerve-lymph microenvironment and closed-loop photoacoustic regulation and control are achieved.

According to the super-resolution polarized light acoustic imaging device and method, galvanometer scanning is achieved on the surface of a sample, excitation light is modulated in different linear polarization directions on each scanning point on the surface of the sample, and the intensity of photoacoustic signals generated by the sample under the excitation light in the different linear polarization directions is obtained through measurement; an initial photoacoustic image of a sample surface structure is constructed by utilizing photoacoustic signal intensities under exciting light in different linear polarization directions, and the initial photoacoustic image is subjected to phase-locked amplification and three-dimensional deconvolution processing, so that a super-resolution photoacoustic image in each linear polarization state is obtained. Compared with traditional polarized light acoustic imaging, the method has the advantages that the diffraction limit of traditional photoacoustic imaging can be overcome, super-resolution imaging of the surface structure of the sample can be achieved while unmarked imaging is achieved, and finer expression of the structure of the sample is achieved. The method has potential application prospects in the fields of biological imaging and biological tissue surface structure conformation detection.

The invention discloses a preparation method of a silicon dioxide-epoxy resin composite material, the acoustic impedance of the composite material is controlled by adjusting the volume fraction of the silicon dioxide-epoxy resin composite material, an ultrasonic transducer prepared by utilizing the composite material and a preparation process thereof, and an imaging system designed by utilizing the ultrasonic transducer. By designing the matching layer and the backing layer with specific acoustic impedance, seamless fusion of ultrasonic imaging and photoacoustic imaging is realized, the transducer has ultrahigh sensitivity, broadband characteristic and high optical transparency, shows bimodal imaging capability of high contrast and high resolution, and solves the problem that a traditional transparent ultrasonic transducer is insufficient in acoustic performance.

The invention discloses non-contact photoacoustic imaging equipment and method based on leakage Lamb wave detection, in the equipment, a photoacoustic excitation unit excites Lamb waves on the surface of a to-be-detected plate-shaped sample through a photoacoustic effect; the automatic scanning unit drives the to-be-detected plate-shaped sample to move along the scanning direction, so that the two-dimensional full-coverage scanning of the to-be-detected plate-shaped sample by the photoacoustic excitation unit is realized; the signal detection and amplification unit captures the leakage Lamb wave signal and carries out signal amplification; the data acquisition unit acquires the amplified signal in real time and transmits the signal data to the signal processing and imaging end; and the signal processing and imaging end is respectively in communication connection with the photoacoustic excitation unit, the automatic scanning unit and the data acquisition unit, and performs signal acquisition, storage, analysis and imaging processing. The photoacoustic effect excitation technology, the high-sensitivity signal detection technology and the automatic scanning imaging technology are fused, and efficient, accurate and non-contact detection of the surface and subsurface defects of the plate-shaped material is achieved.

The invention provides an electroencephalogram and photoacoustic imaging combined detection device, and relates to the technical field of medical information detection. The joint detection device comprises a conductive composite layer suitable for releasing conductive gel in a state of being in contact with skin; the electroencephalogram electrode is embedded in the conductive composite layer and is suitable for transmitting an electroencephalogram signal to an external signal acquisition device when the conductive composite layer is in contact with the skin; the light-induced ultrasonic transmitter is embedded in one end of the conductive composite layer and is constructed to be capable of converting light energy into ultrasonic energy so as to send out an ultrasonic signal and detect nerves and blood vessels under the skin; and the photoinduced ultrasonic receiver is embedded at the other end of the conductive composite layer and is suitable for receiving the ultrasonic signal reflected by the nerve blood vessel and obtaining the spatial information of the nerve blood vessel by using the reflected ultrasonic signal, so that the spatial information of the nerve blood vessel is associated with the electroencephalogram signal, and an electroencephalogram with a target temporal-spatial resolution is obtained.

The disclosure relates to a handheld device (1) and system for optoacoustic imaging of an object (3), the device (1) comprising a housing (2) configured to be grasped by an operator's hand and guided and / or positioned by the operator relative to the object (3) during imaging, wherein the following components are integrated in and / or provided on the housing: a) an illumination unit (4, 6) configured to illuminate the object (3) with time-varying electromagnetic radiation (5), the illumination unit (4, 6) comprising at least one radiation source (4, 6), in particular at least one laser diode (LD), vertical-cavity surface-emitting laser (VCSEL) or light-emitting diode (LED), having a front side (4a) and a back side (4b) opposite the front side and configured to emit the electromagnetic radiation (5) at the front side (4a) of the at least one radiation source (4), the illumination unit (4, 6) further comprising a first electronic controller (6) provided at the back side (4b) of and / or close to the at least one radiation source (4) and configured to control the at least one radiation source (4) to emit pulses of electromagnetic radiation (5) exhibiting at least one of a predefined electromagnetic spectrum and / or wavelength(s), pulse amplitude, pulse shape, pulse width (duration) and / or pulse repetition rate, and b) a detection unit (7, 9) configured to detect ultrasonic waves (8) emanating from the object (3) in response to illuminating the object (3) with the time-varying electromagnetic radiation (5), the detection unit (7, 9) comprising at least one ultrasonic transducer (7), in particular at least one micromachined ultrasonic transducer (MUT) and / or at least one piezoelectric ultrasonic transducer (PUT), having a front side (7a) and a back side (7b) opposite the front side and configured to convert ultrasonic waves (8) impinging at the front side (7a) of the at least one ultrasonic transducer (7) into detection signals, the detection unit (7, 9) further comprising a second electronic controller (9) provided at the back side (7b) of the at least one ultrasonic transducer (7) and configured to process the detection signals, in particular to digitize and / or filter the detection signals and to reconstruct an image of the object (3) based on the digitized and / or filtered detection signals.

The invention relates to the technical field of biomedical imaging, and discloses a photoacoustic-ultrasonic volume imaging method and system based on an annular ultrasonic array, and the method comprises the steps: reconstructing a two-dimensional photoacoustic image and a two-dimensional ultrasonic image; after photoacoustic imaging and ultrasonic synthetic aperture imaging of one imaging plane are completed, the annular ultrasonic array is moved in the direction perpendicular to the imaging plane, photoacoustic images and ultrasonic images of all the imaging planes are repeatedly executed on the next imaging plane, rebuilt and stacked, and a three-dimensional photoacoustic volume image and a three-dimensional ultrasonic volume image are formed; performing spatial pulse response deconvolution processing on the three-dimensional photoacoustic volume image; and fusing the processed three-dimensional photoacoustic volume image and the three-dimensional ultrasonic volume image to generate a three-dimensional bimodal volume image. According to the invention, high-time-resolution opto-acoustic-ultrasonic bimodal three-dimensional imaging is realized by using an annular ultrasonic array and motion scanning, and the high spatial resolution of the image is further ensured through a series of technologies.

The invention discloses a blood vessel ultrasonic enhancement method and device, electronic equipment and a storage medium. The method comprises the following steps: acquiring imaging data of subcutaneous blood vessels; performing reconstruction processing on the imaging data to obtain an imaging image; training data are obtained based on imaging image construction; performing iterative training on a pre-constructed network model by using the training data based on the binary label to obtain a target enhancement model; the network model comprises a coding structure and a decoding structure; and performing enhancement processing on the to-be-enhanced vascular ultrasound image by using the target enhancement model to obtain an ultrasound enhancement result. According to the method, photoacoustic imaging is utilized to make up for the defects of contrast and resolution of a clinical diasonograph in recognition of a blood vessel image, the processes of deep learning and manual annotation removal are combined, an algorithm model for enhancing the blood vessel ultrasonic image is trained with the photoacoustic image as a fact benchmark, efficient and accurate blood vessel ultrasonic enhancement is achieved, and the accuracy of blood vessel ultrasonic enhancement is improved. The method can be widely applied to the technical field of ultrasonic image processing.

The invention discloses a photoacoustic imaging method and a photoacoustic imaging system, and the method comprises the steps: transmitting laser to an imaging target, and receiving a photoacoustic signal returned by the imaging target; determining the light intensity of the laser, and determining the absorption coefficient of the skin layer of the imaging target according to the photoacoustic signal and the light intensity of the laser; obtaining a luminous flux distribution result corresponding to the absorption coefficient of the skin layer, wherein the luminous flux distribution result is used for representing luminous flux distribution conditions of the biological tissue under different imaging depths; acquiring photoacoustic image data of the imaging target; compensating the photoacoustic image data based on the luminous flux distribution result to obtain compensated photoacoustic image data; and generating a photoacoustic image according to the compensated photoacoustic image data. The photoacoustic data is compensated according to the luminous flux distribution result corresponding to the absorption coefficient of the skin layer, and the quality and precision of the photoacoustic image can be improved.

The invention belongs to the field of laparoscopes, and particularly relates to an integrated multi-modal image fusion laparoscope system which comprises a laparoscope body, a multi-modal image acquisition module, an image fusion processing module, a display control module and an energy supply module. The laparoscope body is integrally designed, and a plurality of image acquisition probes are arranged at the front end of the laparoscope body and used for acquiring image information in different modes; corresponding optical conduction and signal transmission lines are integrated in the lens body, so that acquired image information can be stably and efficiently transmitted to a rear-end module; the multi-mode image acquisition module comprises a white light imaging unit, a fluorescence imaging unit, an ultrasonic imaging unit and a photoacoustic imaging unit which are respectively used for acquiring image data of different modes. The system is reasonable in design, provides comprehensive operation area information for doctors by integrating various image modalities and realizing efficient fusion, improves the operation precision and operation efficiency, and is high in expandability.

A medical system includes an elongate vascular device having an optical fiber and a sensor module configured to detect pressure pulses at the skin surface resulting light pulses projected from a distal tip of the optical fiber within the vasculature of a patient. Logic of a system console processes pressure pulse data using photo-acoustic imaging techniques to obtain an image the vasculature. The processing also can include determining properties of the vasculature, such as a cross-sectional size of the vasculature, and determines therefrom a location of the distal tip.

A method operable to track reconstruction of a tissue volume from disjoint acoustic sensors. The method includes placing modular acoustic elements individually at positions with respect to the tissue volume, tracking the positions of the modular acoustic elements individually, creating a volumetric distribution map of the tracked modular acoustic elements, registering the volumetric distribution map, and reconstructing an image of the tissue volume or transmit a focused ultrasound by providing the registered distribution map to a beamforming algorithm.

The invention discloses a visual multifunctional injectable hydrogel with endogenous and endogenous stimulation responsiveness as well as a preparation method and application of the visual multifunctional injectable hydrogel. The hydrogel is mainly prepared from oxygen vacancy molybdenum oxide nanoparticles Ce6-coated PEG-MoOx, transglutaminase and gelatin, wherein the oxygen vacancy molybdenum oxide nanoparticles Ce6-coated PEG-MoOx are loaded with a photosensitizer chlorin e6 and are modified by polyethylene glycol. The hydrogel disclosed by the invention can be applied to preparation of anti-inflammatory, anti-infection or wound repair promoting medicines, especially medicines for treating periodontitis or oral infection. The visible multifunctional injectable hydrogel with endogenous and endogenous stimulus responsiveness, which is constructed by the invention, can be developed through photoacoustic imaging, can play a role of a contrast agent, presents a morphological structure of an area in which the hydrogel is located, can eliminate negative oxidative stress of tissues, can efficiently and quickly kill bacteria, and can be used for preparing a medical dressing for treating endogenous and endogenous stimulus responsiveness. The inorganic signal molecules are controlled in a long-acting and controlled-release manner to play anti-inflammatory and angiogenesis promoting roles, so that tissue healing is promoted.

A multimodal fusion detection apparatus and method based on optical pumping and photoacoustic imaging are provided, relating to the field of fusion detection technology. In the apparatus, the atomic vapor cell detection path and the first laser irradiation path are both directed toward a target region and at least partially overlap. In this way, the detection paths of optical pumping and photoacoustic imaging are at least partially coincident, ensuring that electrophysiological signals and blood oxygen signals originate from the same tissue region and avoiding the spacing constraints of conventional sensors. Thus, the detection path of the atomic vapor cell can be used for both magnetic field detection and photoacoustic detection, enabling simultaneous acquisition of magnetic and photoacoustic signals at a single detection point, achieving hardware reuse for multimodal fusion detection at the same location and time, reducing device size, and minimizing crosstalk among multimodal sensors.

The invention discloses a handheld device and method for tomography photoacoustic imaging of an object. The handheld device comprises a photoacoustic imager body. An angle-adjustable rotating mechanism is arranged at the bottom of the photoacoustic imager body, and a direction-adjustable rotating mechanism is arranged at the bottom of the rotating mechanism; through cooperative arrangement of the rotating mechanism and the rotating mechanism, the device has the advantage of adjusting the angle and the direction in the tomography process of an object, not only can people conveniently carry out handheld operation, but also the posture and the direction of the angle can be continuously kept in the using process, the stability in the continuous tomography process is guaranteed, and the practicability is high. Angle adjustment is achieved through cooperation among the supporting assembly, the rotating assembly and the positioning assembly in the rotating mechanism, locking operation can be achieved after adjustment, direction adjustment is achieved through cooperation among the connecting assembly, the limiting assembly and the elastic assembly in the rotating mechanism, meanwhile, direction locking can be achieved after adjustment, and the use requirements of people are met.