Rapid three-dimensional photoacoustic imaging system based on ultrasonic plane array detector and method thereof
An ultrasonic detector and photoacoustic imaging technology, which is applied in the generation of ultrasonic/sonic/infrasonic waves, and the use of sound waves/ultrasonic/infrasonic waves to analyze solids, etc., can solve the problem of affecting the reliability and authenticity of reconstructed image imaging results, which is difficult to achieve Problems such as fast and real-time imaging, experimental equipment and imaging algorithms are complex, to achieve the effect of being widely used and overcoming slow imaging speed and high contrast
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Embodiment 1
[0034] Embodiment 1 The device and image algorithm of the present invention
[0035] Fig. 1 is the schematic diagram of the principle structure of the whole set of imaging device of the present invention, and this device is made up of four major parts, is respectively photoacoustic signal generation device, photoacoustic signal acquisition and transmission equipment, control probe translation equipment, computer component; connect. The laser 1-1 of the photoacoustic signal generating device is an Nd:YAG pumped OPO laser (Vibrant 532 I, Opotek, Carlsbad, Calif.), the output laser wavelength is 690-960nm, the pulse width is 10ns, and the repetition frequency is 10Hz . The OPO emits a pulsed laser beam, which passes through the mirror 2-1 twice and is divided into a beam of reflected light and a beam of transmitted light by the beam splitter 2-2 at an incident angle of 45°; two beams of equal energy are respectively placed symmetrically and vertically After the reflection mirro...
Embodiment 2
[0038] Embodiment 2 The device and method of Embodiment 1 are used to realize the photoacoustic imaging of the transverse section of the simulated sample.
[0039] First, mix 13% gelatin, 12.5% milk, and 74.5% water to make a square model, and then select two hairs with a length of about 6mm and a size of 100um and bury them in the model with a depth of 5mm. The root hair is placed horizontally and parallel to the plane detector 3-1, with a distance of about 4mm. At the same time, the position of the detector 3-1 is fixed above the sample 2-3 and the distance between the detector 3-1 and the hair plane is adjusted to 4mm. . In the experiment, the operating frequency of OPO laser 1-1 is 15Hz, the pulse width is 10ns, and the wavelength is 532nm. The pulsed laser beam passes through the optical path of the device and evenly covers the two hairs. The photoacoustic signal generated by the excitation is received by the planar detector 3-1, and after the pre-filtering and prevent...
Embodiment 3
[0040] Embodiment 3 The device and method of Embodiment 1 are used to realize the photoacoustic imaging of the longitudinal section of the simulated sample.
[0041] Similar to Example 2, two hair strands of the same size and size as in Example 2 are also placed in a model with the same composition, and the two hair strands are placed parallel to each other in a certain plane perpendicular to the detector 3-1 , the same distance is 4mm. The distances from the detector 3-1 to the two hairs are 28mm and 32mm respectively. The experimental laser 1-1 works at a frequency of 15 Hz, a pulse width of 10 ns, and a wavelength of 532 nm. After splitting, the two laser beams uniformly irradiate the sample 2-3 at different depths, and the generated photoacoustic signal is received by the detector 3-1, preprocessed by the parallel acquisition system 4-1, and then transmitted to the computer 5-1 Complete image reconstruction. Figure 5(a) and (b) show the longitudinal reconstructed tomogr...
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