Image reconstruction method for photoacoustic imaging in random scanning mode

A photoacoustic imaging and image reconstruction technology, applied in image data processing, 2D image generation, acoustic wave diagnosis, etc., can solve problems such as limited scanning methods

Inactive Publication Date: 2012-01-04
FUDAN UNIV
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  • Abstract
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Problems solved by technology

[0004] The above image reconstruction methods are limited to specific scanning methods in practical applications.

Method used

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  • Image reconstruction method for photoacoustic imaging in random scanning mode
  • Image reconstruction method for photoacoustic imaging in random scanning mode
  • Image reconstruction method for photoacoustic imaging in random scanning mode

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Embodiment Construction

[0036] A simulation experiment was carried out on a computer. First, establish the model of the tissue to be imaged, set the known light absorption distribution map, and calculate the photoacoustic signals collected under the conditions of circular scanning, linear scanning and irregular scanning respectively according to (2), and the circular scanning radius is 42 mm , with an angular step of 18°, a total of 20 sampling points; a linear scan with an interval of 4.42 mm, a total of 20 sampling points; an irregular scan with a total of 20 sampling points, which are distributed around the tissue and do not conform to any geometric shape. The light absorption coefficient map of the tissue to be imaged is reconstructed with the simulated ultrasound signal.

[0037] figure 2 The light absorption coefficient map of the tissue to be imaged is shown, the tissue size is 89.6 mm × 89.6 mm, and the reconstructed image size is 128 × 128 pixels.

[0038] image 3 shows the optical abso...

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Abstract

The invention belongs to the technical field of photoacoustic imaging, in particular to an image reconstruction method applicable for photoacoustic imaging in a random scanning mode. In the method, a reconstructed image is obtained by calculating a residual error between a projection signal and an actual signal of the reconstructed image, modifying and iterating the reconstructed image, comprehensively taking the characteristics of total variation sparsity in an iterating process into consideration, and combining a total variation gradient descent method. By the method, a photoacoustic image can be reconstructed precisely in the random scanning mode, so that the method has practical using significance.

Description

technical field [0001] The invention belongs to the technical field of photoacoustic imaging, and in particular relates to an image reconstruction method suitable for photoacoustic imaging in any scanning mode. Background technique [0002] Photoacoustic imaging is a new type of biomedical imaging technology that has developed rapidly in recent years and has gained widespread attention [1,2] , is a hot topic in the international academic circles. Photoacoustic imaging combines the high contrast of optical imaging with the high penetration depth of ultrasound imaging [2] , and was attempted for tumor detection [3] , Angiography [4] and other fields. In addition, photoacoustic imaging is not only suitable for structural imaging, but also for functional imaging. Related experiments were carried out in the brain of mice [5] . [0003] In photoacoustic imaging, short-pulse laser light is used to irradiate biological tissue, so that the tissue absorbs the incident light ener...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T11/00A61B8/00
Inventor 汪源源张砚李伟张建秋李旦胡波
Owner FUDAN UNIV
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