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Compound injection of Xylazine and preparation technique

The technology of thiazide and injection is applied in the field of veterinary drug preparation, can solve the problems of danger, large toxic and side effects, large injection dosage, etc., and achieves the effects of easy use and low cost

Inactive Publication Date: 2009-07-15
闫章年
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In actual use, when dihydroetorphine hydrochloride and xylazine are used alone as anesthetics, there are disadvantages of excessive injection dosage, relatively large toxic and side effects, and considerable danger.
[0005] After searching, there is no literature report on the application of dihydroetorphine hydrochloride and xylazine as a compound preparation for animal anesthesia

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Put 100g of thiarazine and 61g of ethylenediaminetetraacetic acid into double-distilled water, dissolve at 60-70°C, take dihydroetorphine hydrochloride at a ratio of 2500:1 and mix the solution evenly to make a thiaperamide-containing solution per ml. A mixed solution of 100 mg of perazine, 61 mg of ethylenediaminetetraacetic acid, and 20 μg of dihydroetorphine hydrochloride is filled in an ampoule and sterilized.

Embodiment 2

[0019] Put 100g of thiarazine and 66g of ethylenediaminetetraacetic acid into double-distilled water, dissolve at 70-90°C, take dihydroetorphine hydrochloride at a ratio of 5000:1 and mix the solution evenly to make a thiaperazine-containing solution per ml. A mixed solution of 100 mg of perazine, 66 mg of ethylenediaminetetraacetic acid, and 20 μg of dihydroetorphine hydrochloride is filled in an ampoule and sterilized.

Embodiment 3

[0021] Put 100g of thiarazine and 64g of ethylenediaminetetraacetic acid into double-distilled water, dissolve at 65-80°C, take dihydroetorphine hydrochloride at a ratio of 4500:1 and mix the solution evenly to make a thiaperazine-containing solution per ml. A mixed solution of 100 mg of perazine, 64 mg of ethylenediaminetetraacetic acid, and 15 μg of dihydroetorphine hydrochloride is filled in an ampoule and sterilized.

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PUM

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Abstract

The invention provides a compound xiarazine injection and its preparation process. Put 100g of xylazine and 61-66g of ethylenediaminetetraacetic acid into double-distilled water, dissolve them at a temperature of 60-90°C, and prepare them according to the ratio of 5000-2500:1. Take dihydroetorphine hydrochloride and mix the solution evenly to make a mixed solution containing 100 mg of xylazine, 61-66 mg of ethylenediaminetetraacetic acid, and 10-20 μg of dihydroetorphine hydrochloride per ml, and fill it in an ampoule. Sterilized prepared. The invention provides a powerful braking drug for anesthesia and braking of wild animals, which can be used in industrial production and promote artificial breeding and wild animal protection.

Description

Technical field: [0001] The preparation of the invention is an anesthetic drug for animals, and further provides a compound xylazine injection and a preparation process, belonging to the technical field of veterinary drug preparation. technical background: [0002] Thiazine (chemical name 2-(2,6-xylidine amino)-4-H-5,6-dihydro-1,3 thiazine) involved in the present invention is a veterinary medicine used for analgesia, hypnosis and muscle relaxation. Drugs are non-narcotic analgesics and sedatives used to anesthetize animals. They are usually unilateral preparations, and their anesthesia speed is relatively slow. In actual use, in order to quickly anesthetize animals, the amount of anesthesia drugs is often used in a very large amount. Anesthetizing animals comes with many side effects. [0003] Dihydroetorphine hydrochloride (chemical name 7a-[1-(R)-hydroxy-1-methylbutyl] 6,14-endetrahydrooripavine hydrochloride) is a highly effective narcotic sedative Pain medicine, for m...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/54A61K31/485A61K9/08A61P23/00
Inventor 闫章年
Owner 闫章年
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