Tree plant oil women's medical sanitary tampon and method of preparing the same

A technology of tea tree oil and sanitary suppository, which is applied in the field of women's medical sanitary suppository and its preparation, can solve the problems of drug suppository side effects, inconvenient large-scale production, complex preparation process, etc., and achieve increased absorption, good in vitro antibacterial, and uniform texture Effect

Inactive Publication Date: 2009-12-30
中国生化制药工业协会
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The object of the present invention is to provide a kind of tea tree oil medical sanitary suppository with antibacterial, anti-inflammatory, and treatment of women's vaginitis, which not only solves the toxic and side effects brought by drug suppositories and the shortcomings of drug resistance, but also solves the problems in the prior art. Glycerin gelatin matrix is ​​not only easy to lose water, but also easy to absorb water and mold, and the preparation process is complicated, which is not convenient for large-scale production.

Method used

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  • Tree plant oil women's medical sanitary tampon and method of preparing the same
  • Tree plant oil women's medical sanitary tampon and method of preparing the same
  • Tree plant oil women's medical sanitary tampon and method of preparing the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 118

[0095] [Example 1] Preparation of 18% tea tree oil women's medical tampon

[0096] Weigh 820 grams of S-40 into a beaker, melt it quickly in a water bath, then pour 180 grams of tea tree oil into it, and stir evenly to obtain a molten mixture; slowly pour the molten mixture into the mold until it overflows slightly. degree, but it should be finished at one time to avoid solidification and stratification. After cooling and solidifying, scrape the mold to obtain the sanitary tampon.

Embodiment 2

[0097] [Example 2] Preparation of 20% tea tree oil women's medical tampon

[0098] 1) Weigh 800 grams of S-40 into a beaker, melt it quickly in a water bath at 54°C, and it becomes a colorless transparent liquid;

[0099] 2) When the temperature of the water bath is lowered to 50°C, pour in 200 grams of tea tree oil and stir evenly. Then cool down to about 47°C while stirring, when the texture becomes translucent and slightly viscous;

[0100] 3) Heat the mold in a 40°C oven in advance, and coat the inner wall of the mold with liquid paraffin before filling the mold, so that the suppository and the mold can be easily separated during demoulding;

[0101] 4) Slowly pour the molten mixture into the mold to the extent that it slightly overflows the die mouth, but it must be poured at one time to avoid solidification and stratification. Scrape the mould, cool and solidify naturally at room temperature, take it out of the mould, and put it in a 4°C refrigerator for half an hour t...

Embodiment 3

[0103] [Example 3] Preparation of 10% tea tree oil women's medical tampon

[0104] 1) Put the mold into a 40°C oven to heat, and coat the inner wall of the mold with liquid paraffin before filling the mold, so that the suppository and the mold can be easily separated during demoulding;

[0105] 2) Weigh 900 grams of S-40 into a beaker, melt it quickly in a water bath at 53°C, and it becomes a colorless transparent liquid;

[0106] 3) When the temperature of the water bath is lowered to 49° C., pour 100 grams of tea tree oil into the above-mentioned transparent liquid, and stir evenly. Then cool down to about 46°C while stirring. When the texture becomes translucent and slightly viscous, slowly pour the molten mixture into the mold to the extent that it slightly overflows the mold mouth, but it must be poured all at once to avoid solidification. layered. After natural cooling and solidification at room temperature, scrape the mold, and then put it in a refrigerator at 4°C for...

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Abstract

The invention relates to a medical hygiene suppository for women formed by blending tea tree oil and suppository matrix and a preparation method thereof, and belongs to the formula and material improvement of medical hygiene articles for women. The suppository comprises tea tree oil 5-20 wt% and water soluble matrix S-40 80-95wt%. The suppository has antibacterial, antiphlogistic and vaginitis treating effects, and avoids the toxic and side effects and the drug tolerance of the medicinal suppository. In the suppository, only water soluble matrix S-40 is used as a medicinal adjuvant, so that the preparation method of the suppository is simple and easy for mechanical production, and the obtained suppository has the advantages of flat appearance, uniform texture, no central fovea, no irritation, good stability, and qualified weight variation and melt-time. In addition, the used matrix can increase the absorption of water insoluble tea tree oil, so as to better exert therapeutic effect.

Description

technical field [0001] The invention relates to a women's medical sanitary suppository composed of tea tree oil mixed with a suppository base and a preparation method thereof, which belongs to the improvement of the formula of women's medical hygiene products. Background technique [0002] Tea Tree Oil (Tea Tree Oil) is a commercial name, according to the botanically correct definition, it should be called Melaleuca alternifolia oil, because it mainly comes from the Myrtaceae (Myrtaceae) Melaleucal. ), the most important one is called Melaleuca alternifolia, and the secondary plants are Melaleuca bracteata, Melaleuca ericifolia, Melaleuca ericifolia, Melaleuca quinqunervia, Melaleuca viridiflora, etc. Melaleuca alternifolia is native to Australia, and is mainly produced in the southeastern coast of Australia. The fresh branches and leaves of Melaleuca alternifolia can be steam distilled to obtain a colorless to light yellow essential oil, which is called Australian tea tree...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/34A61K9/02A61K36/61A61P15/02
Inventor 徐康森杨红淼
Owner 中国生化制药工业协会
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