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Enteric nutritional supplement

A nutrient and enteral technology, applied in pill delivery, metabolic diseases, drug combination, etc., can solve problems such as reflux esophagitis, aspiration pneumonia, etc., and achieve the effect of simplifying operations

Inactive Publication Date: 2012-10-10
MEIJI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, when the fluid food is injected into the stomach as an enteral nutrient, for example, by gastric fistula nutritional supplementation, the fluid food will reflux along the gastroesophagus, often causing vomiting, reflux esophagitis, and aspiration pneumonia

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The case where Na-type carrageenan is added to Enshura

[0032] This example was carried out in a system in which water and Enshura (trade name) were mixed at a ratio of 1:1. First, 3 g of the paste (Na-type carrageenan) was added to 100 ml of water and dissolved completely. Add 100ml of Enshura to it, stir it with a medicine spoon until it is uniform, draw it with a 100ml syringe, and keep it at room temperature for 10 minutes. Thereafter, the solidified Enshura was extruded from the syringe, and its properties were confirmed over time according to Table 1 below.

[0033] The items are "hardness" and water leakage status. "Hardness" is measured by uniaxial compression using Leona produced by Yamaden Corporation. Measure the compressive stress of a plunger with a diameter of 20mm at a speed of 1mm / s and a clearance rate of 5mm. The state of water leakage was confirmed by visual observation and the amount of aqueous solution dripped from the strainer. The results ar...

Embodiment 2

[0037] In the case of adding starch to Na-type carrageenan

[0038] Except the content and addition amount of paste, others are the same as Example 1. The paste is a mixture of Na-type carrageenan and gelatinized starch at a ratio of 1:1, and 7 g is added. The results are shown in Table 2 below.

[0039] Table 2

[0040]

Embodiment 3

[0061] The case of adding protein, lipid, and carbohydrates to Na-type carrageenan

[0062] An example of preparation of physical properties when protein, lipid, and sugar are contained in sodium carrageenan as a semi-solidification agent is given.

[0063] It should be noted that the raw material composition (mixing for checking physical properties by temperature, mixing for checking physical properties by adding water amount) used in this example is shown in Table 4 and Table 5, respectively.

[0064] Table 4

[0065] Mixing for checking physical properties by temperature

[0066] Raw material weight [g]

mix

calcium caseinate

skimmed milk powder

powdered grease

Na type lambda carrageenan

Dextrin

dissolved water

2.2

5.9

3.5

0.4

15.1

72.9

Total weight [g]

100.0

heat [kcal]

100

[0067] table 5

[0068] Mixing for confirmation of physical properties by the amou...

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PUM

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Abstract

It is intended to provide a novel system whereby an enteric nutritional supplement or a thickened liquid food can be solidified so that it can be easily administered within a short period of time without liquefying in the body to thereby lighten a care-giver's burden in tube feeding such as gastrostomic feeding. As the results of studies, it is found out that such a nutritional supplement or a thickened liquid food can be quickly thickened or solidified at a temperature of 40 DEG C or below by using a starch adhesive, which contains as the main component sodium iota-carrageenan, sodium kappa-carrageenan, sodium lambda-carrageenan or a mixture thereof, without melting the starch adhesive by heating. Further, it is confirmed that the product is almost free from water liberation when administered from a syringe. That is, use of the above-described carrageenan as a starch adhesive (a semi-solidifying agent) makes it possible to produce the desired semi-solidified enteric nutritional supplement as described above.

Description

technical field [0001] The present invention relates to semi-solidification of enteral nutrition. More specifically, the present invention relates to enteral nutrition for use in tube-based nutrition supply methods such as gastric fistula nutrition supply methods (through-tube nutrition injection method) for use in tube administration to patients. Techniques applied to solidify or thicken nutrients or concentrated fluid foods, particularly pastes used in techniques for inhibiting gastroesophageal reflux of enteral nutrients or concentrated fluid foods administered to a patient from the patient's stomach to the esophagus The improvement of the material (semi-solidification agent). Background technique [0002] For patients who cannot take food orally, a method of injecting nutrients into the patient's stomach or intestines through a nutrition tube is called transtube nutrition supply (also referred to as transtube nutrition infusion). The nutritional agent administered to th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/36A61K9/00A23L1/05A61K47/42A23L29/20
CPCA23V2002/00A23L1/296A23L33/40A61P1/00A61P3/02A23V2250/5114A23V2250/54246A23V2250/50366A23V2250/50364A61K9/20A61K47/42A61K47/36
Inventor 外山义雄村尾周久
Owner MEIJI CO LTD
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